Muscle Relaxants and Laryngeal Local Anesthetics for Laryngeal Mask Airway Insertion Decreasing Propofol in Elderly (LMA)
Anesthesia, General
About this trial
This is an interventional other trial for Anesthesia, General focused on measuring Muscle relaxants, Laryngeal local anesthetics, Laryngeal mask airway, Laryngeal Masks, LMA, Propofol, Elderly, Aged
Eligibility Criteria
Inclusion Criteria:
- American Society of Anesthesiologists (ASA) physical status I-III
- Age: over 65 years
- Elective orthopedic surgery undergo general anesthesia in supine position
Exclusion Criteria:
- Anticipated difficult airway (Mallampati score 3-4), limited mouth opening, intra-oral and pharyngeal pathology
- Risk of pulmonary aspiration of gastric contents (full stomach)
- Obesity (Body mass index > 35)
- Significant lung abnormalities (low lung compliance, high airway resistance, impaired oxygenation)
- Loosening teeth
- Allergic to Cisatracurium or Lidocaine
- Failure in successful LMA insertion after second attempts
Sites / Locations
- Linkup Chang Gung Memorial HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Placebo Comparator
10% lidocaine spray and cisatracurium group
10% lidocaine spray and placebo of cisatracurium group
Placebo of lidocaine spray and cisatracurium group
Placebo group
The subjects received laryngeal local anesthetics (10% lidocaine spray), intravenous cisatracurium 0.12 mg/kg, and propofol before laryngeal mask airway placement. The predetermined dosage of propofol for the first subject is 1 mg/kg.
The subjects received laryngeal local anesthetics (10% lidocaine spray), intravenous normal saline as a substitute for cisatracurium, and propofol before laryngeal mask airway placement. The predetermined dosage of propofol for the first subject is 1.25 mg/kg.
The subjects received normal saline spray as a substitute for laryngeal local anesthetics (10% lidocaine spray), intravenous cisatracurium 0.12 mg/kg, and propofol before laryngeal mask airway placement. The predetermined dosage of propofol for the first subject is 1 mg/kg.
The subjects received normal saline spray as a substitute for laryngeal local anesthetics (10% lidocaine spray), intravenous normal saline as a substitute for cisatracurium, and propofol before laryngeal mask airway placement. The predetermined dosage of propofol for the first subject is 2 mg/kg.