Nanodiamond-Gutta Percha Composite Biomaterials for Root Canal Therapy (NDGX)
Dental Pulp Diseases, Dental Pulp Necrosis, Nerve Root Pain Nec
About this trial
This is an interventional treatment trial for Dental Pulp Diseases focused on measuring Root Canal Therapy
Eligibility Criteria
Inclusion Criteria:
- All of the patients must be over 18 years of age and in need of non-surgical RCT treatment during the consultation visit.
Exclusion Criteria:
- Molar teeth
- Osteoporosis medication or i.v. bisphosphonates
- Dental material allergies
- Allergic to penicillin and/or amoxicillin
- Have MD consult/medically compromised/prophylaxis needed
Sites / Locations
- University of California, Los Angeles
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Gutta Percha
ND and Amox modified Gutta Percha
Subjects in both arms of the study will be receiving standard of care RCT and routine follow-up examinations/assessments at 6 months, 1 year, and 2 years post RCT. For all the patients into the control arm of the study, the root canals will be filled with gutta percha (current standard of care), using the vertical condensation obturation technique (standard of care RCT technique).
Subjects in both arms of the study will be receiving standard of care RCT and routine follow-up examinations/assessments at 6 months, 1 year, and 2 years post RCT. The difference between the two arms will be the root canal filler material used. The root canals for the treatment arm of the study will be filled with gutta percha at the apical third, gutta percha modified with nanodiamonds and amoxicillin (NDGX) will be used for the middle and coronal thirds.