Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material
Dental Pulp Diseases, Dental Pulp Necrosis, Nerve Root Pain Nec
About this trial
This is an interventional treatment trial for Dental Pulp Diseases focused on measuring Root Canal Therapy
Eligibility Criteria
Inclusion Criteria:
- 18 years old or older when patient is referred to UCLA endodontics department for root canal therapy
- Patient referral to UCLA endodontics department for root canal therapy
Exclusion Criteria:
- preoperative periodontal disease
- prior non-surgical and surgical endodontic treatment
- currently taking medications used to treat osteoporosis or any form of IV biphosphonates
- allergic to dental materials
- dental phobia
- MD consult/medically compromised/prophylaxis needed
- developmental/congenital disorders
- craniofacial disorder/syndromic cases
- low pain tolerance ascertained from past dental experience
- current moderate to severe periodontitis
- previous RCT/initiated pulp therapy
- previous apical surgery
- previous surgical root canal procedure
- with psychiatric and/or mental health history
- poor oral hygiene
- poor diet
- illicit and/or recreational drug use
- complicated dental history
Sites / Locations
- University of California, Los Angeles
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Gutta Percha
Nanodiamond reinforced Gutta Percha
For all the patients in the control arm of the study, standard treatment of care procedures will be given. Root canal therapy will be given according to the vertical obturation technique. The root canals will be filled with standard root canal filler material: gutta percha at the apical third up to and including the coronal third. The tooth will be restored with a crown for posterior teeth, or a composite filling for anterior teeth.
For all the patients in the treatment arm of the study, standard treatment of care procedures will be given. Root canal therapy will be given according to the vertical obturation technique. The difference between the two arms will be the root canal filler material used. The root canals for the treatment arm of the study will be filled with gutta percha at the apical third, Nanodiamond gutta percha (NDGP) in the middle third, and again with gutta percha at the coronal third. The tooth will be restored with a crown for posterior teeth, or a composite filling for anterior teeth.