Nasal Decolonization for Orthopedic Trauma Patients
Surgical Site Infection
About this trial
This is an interventional prevention trial for Surgical Site Infection focused on measuring nasal decolonization, Orthopedic trauma surgery
Eligibility Criteria
Inclusion Criteria:
- Patients undergoing operative fixation of lower extremity fractures at the University of Iowa during the study period.
Exclusion Criteria:
- Patients unable to provide informed consent due to head trauma or dementia.
Sites / Locations
- University of Iowa Hospitals and Clinics
Arms of the Study
Arm 1
Experimental
Nasal povidone-iodine
Intranasal povidone-iodine (PDI PROFEND) will be applied to the patients' noses before orthopedic trauma surgery and after surgery. This intranasal povidone-iodine was developed under the Tentative Final Monograph for Health-Care Antiseptic Drug Products 21 CFR Parts 333 and 369 (Docket # 75N-183H), Federal Register Volume 59, Number 116, Friday, June 17, 1994, Proposed Rules. However, the product need not be controlled like a pharmaceutical drug. The product may be stored and controlled similarly to an iodine or alcohol skin preparation product.