Non Invasive Ventilation and Weaning : VENISE Trial (VENISE)
Weaning, Chronic Respiratory Failure
About this trial
This is an interventional treatment trial for Weaning focused on measuring Mechanical ventilation, Weaning, Noninvasive ventilation, Acute on chronic respiratory failure
Eligibility Criteria
Inclusion Criteria: endotracheal mechanical ventilation for 48 hours or more for acute respiratory failure in chronic respiratory failure patients (obstructive or restrictive disease), patient ready to be weaned (steady respiratory and hemodynamic conditions for 24 hours), spontaneous breathing trial failure occurring between 5 minutes and 2 hours, judged on clinical and/or arterial blood gas tolerance, written informed consent obtained (patient or family) Exclusion Criteria: respiratory and hemodynamic instability initial intubation considered as difficult swallowing disorders suspected inefficient cough bronchial hypersecretion at the weaning time non cooperant patient contra-indications for nasal or facial mask (facial skin lesions,...) recent history of upper gastro-intestinal surgery recent history of myocardial infarction
Sites / Locations
- Rouen University Charles Nicolle Hospital