Normal Oxygenation Versus Hyperoxia in the Intensive Care Unit (ICU) (OXYGEN-ICU)
Nervous System Diseases, Respiratory Tract Diseases, Cardiovascular Diseases
About this trial
This is an interventional treatment trial for Nervous System Diseases focused on measuring Oxygen, Hyperoxia, Intensive care unit, Mortality, Organ dysfunction, Postoperative care
Eligibility Criteria
Inclusion Criteria:
- all patients admitted in a post-operative and medical intensive care unit with expected admission of at least three days. Informed consensus as soon as possible
Exclusion Criteria:
- minority
- patient discharged from ICU and successively re-admitted
- patient enrolled in other studies
- expected survival shorter than 24 hours
Sites / Locations
- Terapia Intensiva Post-operatoria. Azienda Ospedaliero Universitaria Policlinico di ModenaRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Oxygenation, rigorous normal
Oxygen, free conventional
Patients admitted in intensive care unit for 3 days. Administration of the lowest inspiratory fraction dose of oxygen to maintain oxygen peripheral saturation (SpO2) between 94 and 98% or an arterial partial pressure of oxygen (PaO2) between 70 and 100 mmHg. No oxygen addition administer for transports or diagnostic manoeuvres. Conventional clinical criteria for airways control and ventilation technique.
Patients admitted in intensive care units for 3 days. Administration of oxygen inspiratory fractions to maintain SpO2 over 97%, up to a PaO2 of 150 mmHg. Oxygen addition administer for transports or diagnostic manoeuvres. Conventional clinical criteria for airways control and ventilation technique.