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NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors (NOURISH-T+)

Primary Purpose

Obesity, Childhood, Cancer, Survivorship

Status
Recruiting
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
NOURISH-T+
Brief NOURISH-T+
Sponsored by
University of South Florida
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional supportive care trial for Obesity, Childhood

Eligibility Criteria

5 Years - 14 Years (Child)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

Eligible Pediatric Cancer Survivors must be:

  1. 5-14 years of age at enrollment;
  2. Off active treatment for at least 6 months;
  3. At or above the 85th BMI %ile;
  4. Able to complete assessments with the help of clinic staff and the USF research team;
  5. Residing with the participating parent;
  6. Able to engage in PA tailored to current medical status;
  7. NOT taking medications that affect body weight (e.g., steroids) within 6 months of enrollment, and
  8. In remission -- PCS who experience a relapse of cancer during the intervention will be excused from further involvement.
  9. Must be English- or Spanish-speaking

Participating Parents must:

  • Be either biological or adoptive and/or step mothers or fathers and must be permanent legal guardians of the PCS
  • Be at least 18 years old
  • Identifies as the main meal preparer at home
  • Must be English- or Spanish-speaking

Exclusion Criteria:

  • Parents are ineligible if they are non-ambulatory and/or do not reside at least 50% of the time with their participating child.
  • Female parents who are currently pregnant will be excluded from the study.
  • Children are ineligible to participate if they are non-ambulatory. In addition, children who are wards of the state will be excluded from the study.

Sites / Locations

  • Children's National Hospital
  • University of Florida Health SystemRecruiting
  • University of Miami Health SystemRecruiting
  • Nicklaus Children's Hospital
  • USF PediatricsRecruiting
  • Emory UniversityRecruiting
  • Johns Hopkins MedicineRecruiting
  • Washington University School of MedicineRecruiting
  • Hackensack Meridian HealthRecruiting
  • Virginia Commonwealth University

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

NOURISH-T+

EUC - Brief NOURISH-T+

Arm Description

NOURISH-T+ targets parents as agents of change by providing intensive parent skills training emphasizing role modeling of positive health behaviors to foster the development of healthy eating and physical activity in pediatric cancer survivors. The NOURISH-T+ group will have 6 weekly, 1-1.5 hour, manualized sessions delivered using video-conferencing. There will be 2 additional brief sessions where the child will participate along with their parent to promote child engagement. Additionally, there will be one session with a pediatric oncology dietician based out of Nicklaus Children's Hospital who will discuss personalized nutritional strategies. Brief booster sessions at 2-, 4-, 8-, and 10- months will maximize retention and follow-up participation. NOURISH-T+ content is theory-based, manualized, and builds upon strengths of our prior work with NOURISH-T (our pilot) and NOURISH (our work with otherwise healthy overweight and obese children).

The EUC condition (Brief NOURISH-T+) engages parents in one information session moderated by a USF-based interventionist using videoconferencing. Session content is taken from the publicly available We Can! Manual. Parents in this group will receive nationally available web-based brochures on pediatric overweight/obesity on two occasions during the 6 weeks that NOURISH-T+ families participate in the study. Check-ins will take place at 2-, 4-, 8-, and 10- months post-intervention.

Outcomes

Primary Outcome Measures

Change in Child BMI z-score
Height and weight will be measured to obtain BMI z-score for gender and age.
Change in Child BMI z-score
Height and weight will be measured to obtain BMI z-score for gender and age.

Secondary Outcome Measures

Change in Child Physical Activity Behaviors
Waist-worn accelerometers will be worn for one week to calculate average daily step count over one week. Accelerometers objectively measure daily PA, including average steps per day, time spent in moderate-vigorous activity, and sedentary time.
Change in Child Physical Activity Behaviors
Waist-worn accelerometers will be worn for one week to calculate average daily step count over one week. Accelerometers objectively measure daily PA, including average steps per day, time spent in moderate-vigorous activity, and sedentary time.
Change in Child Eating Behaviors
Dietary Recall Automated Self-administered 24-Hour Dietary Recall-2020(ASA24). ASA24 is a highly reliable, computer assisted 24-hour dietary recall interview with animated guides and audio and visual cues to instruct participants and enhance use in low-literacy populations.
Change in Child Eating Behaviors
Dietary Recall Automated Self-administered 24-Hour Dietary Recall-2020(ASA24). ASA24 is a highly reliable, computer assisted 24-hour dietary recall interview with animated guides and audio and visual cues to instruct participants and enhance use in low-literacy populations.
Change in Parent BMI
Height and weight will be measured and used to calculate continuous adult BMI score.
Change in Parent BMI
Height and weight will be measured and used to calculate continuous adult BMI score.

Full Information

First Posted
November 12, 2020
Last Updated
September 26, 2023
Sponsor
University of South Florida
Collaborators
National Cancer Institute (NCI)
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1. Study Identification

Unique Protocol Identification Number
NCT04656496
Brief Title
NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors
Acronym
NOURISH-T+
Official Title
NOURISH-T+: A Randomized Control Trial Targeting Parents in Promoting Healthy Eating and Exercise Behaviors in Pediatric Cancer Survivors With Overweight/Obesity
Study Type
Interventional

2. Study Status

Record Verification Date
September 2023
Overall Recruitment Status
Recruiting
Study Start Date
December 1, 2019 (Actual)
Primary Completion Date
October 30, 2025 (Anticipated)
Study Completion Date
November 30, 2025 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University of South Florida
Collaborators
National Cancer Institute (NCI)

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
Pediatric cancer survivors are at an increased risk of excessive weight gain and reduced exercise behaviors with the potential for this risk to worsen over time. With over 80% of pediatric cancer patients living to adulthood, many pediatric cancer survivors experience long-term health consequences such as heart disease - the leading cause of death in this population. The purpose of this clinical research study is to teach parents/caregivers skills that will help prevent and reduce the problems of obesity in childhood cancer survivors. In this study, parents have the opportunity to participate in one of two web-based groups in which parents in either group will learn valuable information to improve the health of their child and of themselves.
Detailed Description
This project employs a cluster randomized, controlled, repeated measures trial study design, with parent-child dyads assigned to an evidence-informed manualized, social-cognitive parent intervention (NOURISH-T+) or to a comparison group (Enhanced Usual Care group - Brief NOURISH-T+). NOURISH-T+ stands for Nourishing Our Understanding of Role modeling to Improve Support and Health for Healthy Transitions. Parents of pediatric cancer survivors (ages 5-14 years) with overweight and obesity, and off treatment for at least 6 months will be recruited across multiple pediatric oncology clinic sites. The University of South Florida (USF) serves as the coordinating data management and centralized research and intervention team and will also recruit eligible participants from its pediatric oncology clinic. NOURISH-T+ targets parents as agents of change by providing intensive parent skills training emphasizing role modeling of positive health behaviors to foster the development of healthy eating and physical activity in pediatric cancer survivors. The NOURISH-T+ group will have 6 weekly, 1-1.5 hour, manualized sessions delivered using video-conferencing. There will be 2 additional brief sessions where the child will participate along with their parent to promote child engagement. Additionally, there will be one session with a pediatric oncology dietician based out of Nicklaus Children's Hospital who will discuss personalized nutritional strategies. Brief booster sessions at 2-, 4-, 8-, and 10- months will maximize retention and follow-up participation. NOURISH-T+ content is theory-based, manualized, and builds upon strengths of our prior work with NOURISH-T (our pilot) and NOURISH (our work with otherwise healthy overweight and obese children). Parents randomized to Brief NOURISH-T+ will participate in one information session moderated by a USF-based interventionist using videoconferencing. Session content is taken from the publicly available We Can! Manual. Parents in this group will receive nationally available web-based brochures on pediatric overweight/obesity on two occasions during the 6 weeks that NOURISH-T+ families participate in the study. Check-ins will take place at 2-, 4-, 8-, and 10- months post-intervention. Outcome measures will be completed at baseline, 3-, 6-, and 12-months post-intervention.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obesity, Childhood, Cancer, Survivorship

7. Study Design

Primary Purpose
Supportive Care
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Care ProviderOutcomes Assessor
Allocation
Randomized
Enrollment
520 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
NOURISH-T+
Arm Type
Experimental
Arm Description
NOURISH-T+ targets parents as agents of change by providing intensive parent skills training emphasizing role modeling of positive health behaviors to foster the development of healthy eating and physical activity in pediatric cancer survivors. The NOURISH-T+ group will have 6 weekly, 1-1.5 hour, manualized sessions delivered using video-conferencing. There will be 2 additional brief sessions where the child will participate along with their parent to promote child engagement. Additionally, there will be one session with a pediatric oncology dietician based out of Nicklaus Children's Hospital who will discuss personalized nutritional strategies. Brief booster sessions at 2-, 4-, 8-, and 10- months will maximize retention and follow-up participation. NOURISH-T+ content is theory-based, manualized, and builds upon strengths of our prior work with NOURISH-T (our pilot) and NOURISH (our work with otherwise healthy overweight and obese children).
Arm Title
EUC - Brief NOURISH-T+
Arm Type
Active Comparator
Arm Description
The EUC condition (Brief NOURISH-T+) engages parents in one information session moderated by a USF-based interventionist using videoconferencing. Session content is taken from the publicly available We Can! Manual. Parents in this group will receive nationally available web-based brochures on pediatric overweight/obesity on two occasions during the 6 weeks that NOURISH-T+ families participate in the study. Check-ins will take place at 2-, 4-, 8-, and 10- months post-intervention.
Intervention Type
Behavioral
Intervention Name(s)
NOURISH-T+
Intervention Description
NOURISH-T+ (Nourishing Our Understanding of Role Modeling to Improve Support and Healthy - Transitions) is a 6 session, psychoeducational program designed to teach parents of childhood cancer survivors with overweight/obesity knowledge and skills to improve the health and lifestyle behaviors for their child and for themselves.
Intervention Type
Behavioral
Intervention Name(s)
Brief NOURISH-T+
Intervention Description
Enhanced Usual Care (or Brief NOURISH-T+) is an abbreviated version of the full NOURISH-T+ intervention in which parents are engaged in a one-time information session to also learn knowledge and skills to improve the health and lifestyle behaviors for their child and for themselves.
Primary Outcome Measure Information:
Title
Change in Child BMI z-score
Description
Height and weight will be measured to obtain BMI z-score for gender and age.
Time Frame
baseline to 6 months
Title
Change in Child BMI z-score
Description
Height and weight will be measured to obtain BMI z-score for gender and age.
Time Frame
baseline to 12 months
Secondary Outcome Measure Information:
Title
Change in Child Physical Activity Behaviors
Description
Waist-worn accelerometers will be worn for one week to calculate average daily step count over one week. Accelerometers objectively measure daily PA, including average steps per day, time spent in moderate-vigorous activity, and sedentary time.
Time Frame
baseline to 6 months
Title
Change in Child Physical Activity Behaviors
Description
Waist-worn accelerometers will be worn for one week to calculate average daily step count over one week. Accelerometers objectively measure daily PA, including average steps per day, time spent in moderate-vigorous activity, and sedentary time.
Time Frame
baseline to 12 months
Title
Change in Child Eating Behaviors
Description
Dietary Recall Automated Self-administered 24-Hour Dietary Recall-2020(ASA24). ASA24 is a highly reliable, computer assisted 24-hour dietary recall interview with animated guides and audio and visual cues to instruct participants and enhance use in low-literacy populations.
Time Frame
baseline to 6 months
Title
Change in Child Eating Behaviors
Description
Dietary Recall Automated Self-administered 24-Hour Dietary Recall-2020(ASA24). ASA24 is a highly reliable, computer assisted 24-hour dietary recall interview with animated guides and audio and visual cues to instruct participants and enhance use in low-literacy populations.
Time Frame
baseline to 12 months
Title
Change in Parent BMI
Description
Height and weight will be measured and used to calculate continuous adult BMI score.
Time Frame
baseline to 6 months
Title
Change in Parent BMI
Description
Height and weight will be measured and used to calculate continuous adult BMI score.
Time Frame
baseline to 12 months

10. Eligibility

Sex
All
Minimum Age & Unit of Time
5 Years
Maximum Age & Unit of Time
14 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Eligible Pediatric Cancer Survivors must be: 5-14 years of age at enrollment; Off active treatment for at least 6 months; At or above the 85th BMI %ile; Able to complete assessments with the help of clinic staff and the USF research team; Residing with the participating parent; Able to engage in PA tailored to current medical status; NOT taking medications that affect body weight (e.g., steroids) within 6 months of enrollment, and In remission -- PCS who experience a relapse of cancer during the intervention will be excused from further involvement. Must be English- or Spanish-speaking Participating Parents must: Be either biological or adoptive and/or step mothers or fathers and must be permanent legal guardians of the PCS Be at least 18 years old Identifies as the main meal preparer at home Must be English- or Spanish-speaking Exclusion Criteria: Parents are ineligible if they are non-ambulatory and/or do not reside at least 50% of the time with their participating child. Female parents who are currently pregnant will be excluded from the study. Children are ineligible to participate if they are non-ambulatory. In addition, children who are wards of the state will be excluded from the study.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Marilyn Stern, PhD
Phone
813-974-0966
Email
mstern1@usf.edu
First Name & Middle Initial & Last Name or Official Title & Degree
Flandra Ismajli, BSW
Phone
813-974-6135
Email
flandraismaj@usf.edu
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Marilyn Stern, PhD
Organizational Affiliation
University of South Florida
Official's Role
Principal Investigator
Facility Information:
Facility Name
Children's National Hospital
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20010
Country
United States
Individual Site Status
Suspended
Facility Name
University of Florida Health System
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32611
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Tung T Wynn, MD
Phone
352-273-9120
Email
twynn@ufl.edu
First Name & Middle Initial & Last Name & Degree
Clancy B Stargel, MS
Email
clancy.bryant@peds.ufl.edu
Facility Name
University of Miami Health System
City
Miami
State/Province
Florida
ZIP/Postal Code
33136
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Winsome Thompson, PhD
Email
wthompson1@med.miami.edu
First Name & Middle Initial & Last Name & Degree
Olena Ashworth
Email
osa5040@med.miami.edu
Facility Name
Nicklaus Children's Hospital
City
Miami
State/Province
Florida
ZIP/Postal Code
33155
Country
United States
Individual Site Status
Suspended
Facility Name
USF Pediatrics
City
Tampa
State/Province
Florida
ZIP/Postal Code
33612
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Andrew Galligan, MD
Email
agalligan@usf.edu
Facility Name
Emory University
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30322
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jordan Marchak, PhD
Phone
404-727-2293
Email
jgillel@emory.edu
First Name & Middle Initial & Last Name & Degree
Ebonee Harris
Email
ebonee.harris@choa.org
Facility Name
Johns Hopkins Medicine
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21287
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kathy Ruble, PhD
Phone
410-502-2092
Email
rubleka@jhmi.edu
First Name & Middle Initial & Last Name & Degree
Destiny Walker
Email
dwalke64@jhmi.edu
First Name & Middle Initial & Last Name & Degree
Kathy Ruble, PhD
Facility Name
Washington University School of Medicine
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63110
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shalini Shenoy, MD
Email
shalinishenoy@wustl.edu
First Name & Middle Initial & Last Name & Degree
Kara Felts
Phone
314-286-1177
Email
feltsk@wustl.edu
Facility Name
Hackensack Meridian Health
City
Hackensack
State/Province
New Jersey
ZIP/Postal Code
07601
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Katharine R Lange, MD
Phone
201-487-8987
Email
katharine.lange@hmhn.org
First Name & Middle Initial & Last Name & Degree
Alexis Dompor
Phone
551-996-4781
Email
alexis.dompor@hmhn.org
Facility Name
Virginia Commonwealth University
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23298
Country
United States
Individual Site Status
Suspended

12. IPD Sharing Statement

Plan to Share IPD
No
Citations:
PubMed Identifier
24577544
Citation
Ruble K, Davis CL, Han HR. Endothelial health in childhood acute lymphoid leukemia survivors: pilot evaluation with peripheral artery tonometry. J Pediatr Hematol Oncol. 2015 Mar;37(2):117-20. doi: 10.1097/MPH.0000000000000122.
Results Reference
background
PubMed Identifier
26284383
Citation
Ruble K, Scarvalone S, Gallicchio L, Davis C, Wells D. Group Physical Activity Intervention for Childhood Cancer Survivors: A Pilot Study. J Phys Act Health. 2016 Mar;13(3):352-9. doi: 10.1123/jpah.2015-0050. Epub 2015 Aug 13.
Results Reference
background
PubMed Identifier
19255308
Citation
Nathan PC, Ford JS, Henderson TO, Hudson MM, Emmons KM, Casillas JN, Lown EA, Ness KK, Oeffinger KC. Health behaviors, medical care, and interventions to promote healthy living in the Childhood Cancer Survivor Study cohort. J Clin Oncol. 2009 May 10;27(14):2363-73. doi: 10.1200/JCO.2008.21.1441. Epub 2009 Mar 2.
Results Reference
background
PubMed Identifier
17182834
Citation
Stull VB, Snyder DC, Demark-Wahnefried W. Lifestyle interventions in cancer survivors: designing programs that meet the needs of this vulnerable and growing population. J Nutr. 2007 Jan;137(1 Suppl):243S-248S. doi: 10.1093/jn/137.1.243S.
Results Reference
background
PubMed Identifier
8968860
Citation
Reilly JJ, Blacklock CJ, Dale E, Donaldson M, Gibson BE. Resting metabolic rate and obesity in childhood acute lymphoblastic leukaemia. Int J Obes Relat Metab Disord. 1996 Dec;20(12):1130-2.
Results Reference
background
PubMed Identifier
15574725
Citation
Greving DM, Santacroce SJ. Cardiovascular late effects. J Pediatr Oncol Nurs. 2005 Jan-Feb;22(1):38-47. doi: 10.1177/1043454204272531.
Results Reference
background
PubMed Identifier
12663727
Citation
Oeffinger KC, Mertens AC, Sklar CA, Yasui Y, Fears T, Stovall M, Vik TA, Inskip PD, Robison LL; Childhood Cancer Survivor Study. Obesity in adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2003 Apr 1;21(7):1359-65. doi: 10.1200/JCO.2003.06.131.
Results Reference
background
PubMed Identifier
17896787
Citation
Chow EJ, Pihoker C, Hunt K, Wilkinson K, Friedman DL. Obesity and hypertension among children after treatment for acute lymphoblastic leukemia. Cancer. 2007 Nov 15;110(10):2313-20. doi: 10.1002/cncr.23050.
Results Reference
background
PubMed Identifier
11044803
Citation
Mayer EI, Reuter M, Dopfer RE, Ranke MB. Energy expenditure, energy intake and prevalence of obesity after therapy for acute lymphoblastic leukemia during childhood. Horm Res. 2000;53(4):193-9. doi: 10.1159/000023566.
Results Reference
background
PubMed Identifier
18064643
Citation
Warner JT. Body composition, exercise and energy expenditure in survivors of acute lymphoblastic leukaemia. Pediatr Blood Cancer. 2008 Feb;50(2 Suppl):456-61; discussion 468. doi: 10.1002/pbc.21411.
Results Reference
background
PubMed Identifier
19224548
Citation
Ness KK, Leisenring WM, Huang S, Hudson MM, Gurney JG, Whelan K, Hobbie WL, Armstrong GT, Robison LL, Oeffinger KC. Predictors of inactive lifestyle among adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. Cancer. 2009 May 1;115(9):1984-94. doi: 10.1002/cncr.24209.
Results Reference
background
PubMed Identifier
24482072
Citation
Zhang FF, Rodday AM, Kelly MJ, Must A, MacPherson C, Roberts SB, Saltzman E, Parsons SK. Predictors of being overweight or obese in survivors of pediatric acute lymphoblastic leukemia (ALL). Pediatr Blood Cancer. 2014 Jul;61(7):1263-9. doi: 10.1002/pbc.24960. Epub 2014 Jan 30.
Results Reference
background
PubMed Identifier
19117349
Citation
Cox CL, Montgomery M, Oeffinger KC, Leisenring W, Zeltzer L, Whitton JA, Mertens AC, Hudson MM, Robison LL. Promoting physical activity in childhood cancer survivors: results from the Childhood Cancer Survivor Study. Cancer. 2009 Feb 1;115(3):642-54. doi: 10.1002/cncr.24043.
Results Reference
background
PubMed Identifier
17459696
Citation
Clarke SA, Eiser C. Health behaviours in childhood cancer survivors: a systematic review. Eur J Cancer. 2007 Jun;43(9):1373-84. doi: 10.1016/j.ejca.2007.03.002. Epub 2007 Apr 24.
Results Reference
background
PubMed Identifier
24002505
Citation
Armstrong GT, Oeffinger KC, Chen Y, Kawashima T, Yasui Y, Leisenring W, Stovall M, Chow EJ, Sklar CA, Mulrooney DA, Mertens AC, Border W, Durand JB, Robison LL, Meacham LR. Modifiable risk factors and major cardiac events among adult survivors of childhood cancer. J Clin Oncol. 2013 Oct 10;31(29):3673-80. doi: 10.1200/JCO.2013.49.3205. Epub 2013 Sep 3.
Results Reference
background
PubMed Identifier
17035650
Citation
Oeffinger KC, Mertens AC, Sklar CA, Kawashima T, Hudson MM, Meadows AT, Friedman DL, Marina N, Hobbie W, Kadan-Lottick NS, Schwartz CL, Leisenring W, Robison LL; Childhood Cancer Survivor Study. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med. 2006 Oct 12;355(15):1572-82. doi: 10.1056/NEJMsa060185.
Results Reference
background
PubMed Identifier
14506117
Citation
Hudson MM, Mertens AC, Yasui Y, Hobbie W, Chen H, Gurney JG, Yeazel M, Recklitis CJ, Marina N, Robison LR, Oeffinger KC; Childhood Cancer Survivor Study Investigators. Health status of adult long-term survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. JAMA. 2003 Sep 24;290(12):1583-92. doi: 10.1001/jama.290.12.1583.
Results Reference
background
PubMed Identifier
17644535
Citation
Eiser C. Beyond survival: quality of life and follow-up after childhood cancer. J Pediatr Psychol. 2007 Oct;32(9):1140-50. doi: 10.1093/jpepsy/jsm052. Epub 2007 Jul 20.
Results Reference
background
Citation
Green D, Wallace H. Late effects of Childhood Cancer. CRC Press; 2003.
Results Reference
background
PubMed Identifier
15654361
Citation
Smith AW, Baum A, Wing RR. Stress and weight gain in parents of cancer patients. Int J Obes (Lond). 2005 Feb;29(2):244-50. doi: 10.1038/sj.ijo.0802835.
Results Reference
background
PubMed Identifier
24081971
Citation
Lipshultz SE, Adams MJ, Colan SD, Constine LS, Herman EH, Hsu DT, Hudson MM, Kremer LC, Landy DC, Miller TL, Oeffinger KC, Rosenthal DN, Sable CA, Sallan SE, Singh GK, Steinberger J, Cochran TR, Wilkinson JD; American Heart Association Congenital Heart Defects Committee of the Council on Cardiovascular Disease in the Young, Council on Basic Cardiovascular Sciences, Council on Cardiovascular and Stroke Nursing, Council on Cardiovascular Radiolo. Long-term cardiovascular toxicity in children, adolescents, and young adults who receive cancer therapy: pathophysiology, course, monitoring, management, prevention, and research directions: a scientific statement from the American Heart Association. Circulation. 2013 Oct 22;128(17):1927-95. doi: 10.1161/CIR.0b013e3182a88099. Epub 2013 Sep 30. No abstract available. Erratum In: Circulation. 2013 Nov 5;128(19):e394.
Results Reference
background
PubMed Identifier
25564774
Citation
Stolley MR, Sharp LK, Tangney CC, Schiffer LA, Arroyo C, Kim Y, Campbell RT, Schmidt ML, Breen K, Kinahan KE, Dilley KJ, Henderson TO, Korenblit AD, Seligman K. Health behaviors of minority childhood cancer survivors. Cancer. 2015 May 15;121(10):1671-80. doi: 10.1002/cncr.29202. Epub 2015 Jan 6.
Results Reference
background
PubMed Identifier
10918229
Citation
Sklar CA, Mertens AC, Walter A, Mitchell D, Nesbit ME, O'Leary M, Hutchinson R, Meadows AT, Robison LL. Changes in body mass index and prevalence of overweight in survivors of childhood acute lymphoblastic leukemia: role of cranial irradiation. Med Pediatr Oncol. 2000 Aug;35(2):91-5. doi: 10.1002/1096-911x(200008)35:23.0.co;2-g.
Results Reference
background
PubMed Identifier
28130395
Citation
Stern M, Bachar E, Ronen Ackerman E, Rancourt D, Bonne O, Weintraub M. Weight Trajectories of Israeli Pediatric Cancer Survivors. J Pediatr Psychol. 2017 Jun 1;42(5):588-597. doi: 10.1093/jpepsy/jsw102.
Results Reference
background
PubMed Identifier
22253364
Citation
Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA. 2012 Feb 1;307(5):483-90. doi: 10.1001/jama.2012.40. Epub 2012 Jan 17.
Results Reference
background
PubMed Identifier
26374183
Citation
Zhang FF, Parsons SK. Obesity in Childhood Cancer Survivors: Call for Early Weight Management. Adv Nutr. 2015 Sep 15;6(5):611-9. doi: 10.3945/an.115.008946. Print 2015 Sep.
Results Reference
background
PubMed Identifier
19826351
Citation
Moyer A, Knapp-Oliver SK, Sohl SJ, Schnieder S, Floyd AH. Lessons to be learned from 25 years of research investigating psychosocial interventions for cancer patients. Cancer J. 2009 Sep-Oct;15(5):345-51. doi: 10.1097/PPO.0b013e3181bf51fb.
Results Reference
background
PubMed Identifier
15526028
Citation
van Brussel M, Takken T, Lucia A, van der Net J, Helders PJ. Is physical fitness decreased in survivors of childhood leukemia? A systematic review. Leukemia. 2005 Jan;19(1):13-7. doi: 10.1038/sj.leu.2403547.
Results Reference
background
PubMed Identifier
9585006
Citation
Warner JT, Bell W, Webb DK, Gregory JW. Daily energy expenditure and physical activity in survivors of childhood malignancy. Pediatr Res. 1998 May;43(5):607-13. doi: 10.1203/00006450-199805000-00008.
Results Reference
background
PubMed Identifier
22273843
Citation
Mazzeo SE, Kelly NR, Stern M, Gow RW, Serdar K, Evans RK, Jones RM, Bulik CM. Nourishing Our Understanding of Role Modeling to Improve Support and Health (NOURISH): design and methods. Contemp Clin Trials. 2012 May;33(3):515-22. doi: 10.1016/j.cct.2012.01.003. Epub 2012 Jan 18.
Results Reference
background
PubMed Identifier
22675239
Citation
Mackinnon DP. Integrating Mediators and Moderators in Research Design. Res Soc Work Pract. 2011 Nov;21(6):675-681. doi: 10.1177/1049731511414148. Epub 2011 Jul 13.
Results Reference
background
PubMed Identifier
28959085
Citation
Lydecker JA, Simpson C, Kwitowski M, Gow RW, Stern M, Bulik CM, Mazzeo SE. Evaluation of Parent-Reported Feeding Practices in a Racially Diverse, Treatment-Seeking Child Overweight/Obesity Sample. Child Health Care. 2017;46(3):265-281. doi: 10.1080/02739615.2016.1163489. Epub 2016 Mar 17.
Results Reference
background
Citation
Stern, M., Mazzeo, S.E., Porter, J. et al. Self-Esteem, Teasing and Quality of Life: African American Adolescent Girls Participating in a Family-Based Pediatric Overweight Intervention. J Clin Psychol Med Settings 13, 217 (2006). https://doi.org/10.1007/s10880-006-9029-4
Results Reference
background
PubMed Identifier
25559916
Citation
Stern M, Ewing L, Davila E, Thompson AL, Hale G, Mazzeo S. Design and rationale for NOURISH-T: a randomized control trial targeting parents of overweight children off cancer treatment. Contemp Clin Trials. 2015 Mar;41:227-37. doi: 10.1016/j.cct.2014.12.018. Epub 2015 Jan 2.
Results Reference
background
PubMed Identifier
22735041
Citation
Bean MK, Wilson DB, Thornton LM, Kelly N, Mazzeo SE. Dietary intake in a randomized-controlled pilot of NOURISH: a parent intervention for overweight children. Prev Med. 2012 Sep;55(3):224-7. doi: 10.1016/j.ypmed.2012.06.016. Epub 2012 Jun 24.
Results Reference
background
PubMed Identifier
27064243
Citation
Raber M, Swartz MC, Santa Maria D, O'Connor T, Baranowski T, Li R, Chandra J. Parental involvement in exercise and diet interventions for childhood cancer survivors: a systematic review. Pediatr Res. 2016 Sep;80(3):338-46. doi: 10.1038/pr.2016.84. Epub 2016 Apr 11.
Results Reference
background
PubMed Identifier
7805631
Citation
Epstein LH, Valoski A, Wing RR, McCurley J. Ten-year outcomes of behavioral family-based treatment for childhood obesity. Health Psychol. 1994 Sep;13(5):373-83. doi: 10.1037//0278-6133.13.5.373.
Results Reference
background
PubMed Identifier
2232019
Citation
Epstein LH, Valoski A, Wing RR, McCurley J. Ten-year follow-up of behavioral, family-based treatment for obese children. JAMA. 1990 Nov 21;264(19):2519-23.
Results Reference
background
PubMed Identifier
7287977
Citation
Epstein LH, Wing RR, Koeske R, Andrasik F, Ossip DJ. Child and parent weight loss in family-based behavior modification programs. J Consult Clin Psychol. 1981 Oct;49(5):674-85. doi: 10.1037//0022-006x.49.5.674. No abstract available.
Results Reference
background
PubMed Identifier
3106445
Citation
Epstein LH, Wing RR, Koeske R, Valoski A. Long-term effects of family-based treatment of childhood obesity. J Consult Clin Psychol. 1987 Feb;55(1):91-5. doi: 10.1037//0022-006x.55.1.91. No abstract available.
Results Reference
background
PubMed Identifier
14995056
Citation
Golan M, Crow S. Parents are key players in the prevention and treatment of weight-related problems. Nutr Rev. 2004 Jan;62(1):39-50. doi: 10.1111/j.1753-4887.2004.tb00005.x.
Results Reference
background
PubMed Identifier
17907317
Citation
Golan M. Parents as agents of change in childhood obesity--from research to practice. Int J Pediatr Obes. 2006;1(2):66-76. doi: 10.1080/17477160600644272.
Results Reference
background
PubMed Identifier
20063940
Citation
Kitzmann KM, Dalton WT 3rd, Stanley CM, Beech BM, Reeves TP, Buscemi J, Egli CJ, Gamble HL, Midgett EL. Lifestyle interventions for youth who are overweight: a meta-analytic review. Health Psychol. 2010 Jan;29(1):91-101. doi: 10.1037/a0017437.
Results Reference
background
PubMed Identifier
29334983
Citation
Smith JD, Berkel C, Jordan N, Atkins DC, Narayanan SS, Gallo C, Grimm KJ, Dishion TJ, Mauricio AM, Rudo-Stern J, Meachum MK, Winslow E, Bruening MM. An individually tailored family-centered intervention for pediatric obesity in primary care: study protocol of a randomized type II hybrid effectiveness-implementation trial (Raising Healthy Children study). Implement Sci. 2018 Jan 15;13(1):11. doi: 10.1186/s13012-017-0697-2.
Results Reference
background
PubMed Identifier
29350459
Citation
Stern M, Bleck J, Ewing LJ, Davila E, Lynn C, Hale G, Mazzeo S. NOURISH-T: Targeting caregivers to improve health behaviors in pediatric cancer survivors with obesity. Pediatr Blood Cancer. 2018 May;65(5):e26941. doi: 10.1002/pbc.26941. Epub 2018 Jan 19.
Results Reference
background
Citation
Stern, M., Lamanna, J., Russell, C., Ewing, L., Thompson, A., Trapp, S., Bitsko, M., & Mazzeo, S. (2013). Adaptation of an obesity intervention program for pediatric cancer survivors (NOURISH-T). Clinical Practice in Pediatric Psychology, 1(3), 264-275. https://doi.org/10.1037/cpp0000023
Results Reference
background
Citation
Mazzeo S, Gow R, Stern M, Gerke C. Developing an intervention for parents of overweight children. International Journal of Child and Adolescent Health. 2008;1(4):355-363.
Results Reference
background
PubMed Identifier
33515782
Citation
Stern M, Gray HL, Ruble K, Soca Lozano S, Albizu-Jacob A, Williams JM, Godder K, Fuemmeler B, Mazzeo S. A cluster-randomized control trial targeting parents of pediatric cancer survivors with obesity: Rationale and study protocol of NOURISH-T. Contemp Clin Trials. 2021 Mar;102:106296. doi: 10.1016/j.cct.2021.106296. Epub 2021 Jan 27.
Results Reference
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NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors

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