search
Back to results

Nutrition in Pregnancy, Birth Weight, and Childhood Asthma

Primary Purpose

Lung Diseases, Asthma

Status
Completed
Phase
Locations
Study Type
Observational
Intervention
Sponsored by
Harvard Pilgrim Health Care
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an observational trial for Lung Diseases

Eligibility Criteria

undefined - undefined (Child, Adult, Older Adult)All SexesDoes not accept healthy volunteers

No eligibility criteria

Sites / Locations

    Outcomes

    Primary Outcome Measures

    Secondary Outcome Measures

    Full Information

    First Posted
    October 12, 2000
    Last Updated
    March 25, 2014
    Sponsor
    Harvard Pilgrim Health Care
    Collaborators
    National Heart, Lung, and Blood Institute (NHLBI)
    search

    1. Study Identification

    Unique Protocol Identification Number
    NCT00006404
    Brief Title
    Nutrition in Pregnancy, Birth Weight, and Childhood Asthma
    Study Type
    Observational

    2. Study Status

    Record Verification Date
    May 2009
    Overall Recruitment Status
    Completed
    Study Start Date
    September 2000 (undefined)
    Primary Completion Date
    July 2006 (Actual)
    Study Completion Date
    July 2006 (Actual)

    3. Sponsor/Collaborators

    Name of the Sponsor
    Harvard Pilgrim Health Care
    Collaborators
    National Heart, Lung, and Blood Institute (NHLBI)

    4. Oversight

    5. Study Description

    Brief Summary
    To evaluate the role of maternal diet and birth weight in the etiology of childhood asthma and other allergic disorders.
    Detailed Description
    BACKGROUND: Asthma is one of the most common chronic diseases diagnosed among children in the developed world, and its prevalence in western industrialized countries is increasing at an alarming rate. Little information is currently available regarding the role of maternal diet during pregnancy and birth weight in the risk of childhood asthma. DESIGN NARRATIVE: This longitudinal prospective study takes advantage of the resources provided by Project Viva, an ongoing prospective cohort study of pregnant women and their infant offspring among members of Harvard Pilgrim Health Care, a large managed care organization in New England. Data already available from Project Viva include detailed dietary data on mother and infant, along with data on anthropometric, social, environmental, demographic, economic, psychological, and lifestyle variables. The study will follow the Project Viva cohort until ages 3 to 4 years.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Lung Diseases, Asthma

    7. Study Design

    10. Eligibility

    Sex
    All
    Accepts Healthy Volunteers
    No
    Eligibility Criteria
    No eligibility criteria
    Overall Study Officials:
    First Name & Middle Initial & Last Name & Degree
    Matthew Gillman
    Organizational Affiliation
    Harvard Pilgrim Health Care, Inc.

    12. IPD Sharing Statement

    Citations:
    PubMed Identifier
    12907111
    Citation
    Oken E, Kleinman KP, Berland WE, Simon SR, Rich-Edwards JW, Gillman MW. Decline in fish consumption among pregnant women after a national mercury advisory. Obstet Gynecol. 2003 Aug;102(2):346-51. doi: 10.1016/s0029-7844(03)00484-8.
    Results Reference
    background
    PubMed Identifier
    12690076
    Citation
    Oken E, Gillman MW. Fetal origins of obesity. Obes Res. 2003 Apr;11(4):496-506. doi: 10.1038/oby.2003.69.
    Results Reference
    background
    PubMed Identifier
    11980782
    Citation
    Gillman MW. Epidemiological challenges in studying the fetal origins of adult chronic disease. Int J Epidemiol. 2002 Apr;31(2):294-9. No abstract available.
    Results Reference
    background
    PubMed Identifier
    15181194
    Citation
    Schroeter CH, Schaub B, Gold DR, Contreras PJ, Manrique O, Gillman MW, Weiss S, Palmer LJ, Perkins D, Finn PW. Nuclear factor kappa B activation in human cord blood mononuclear cells. Pediatr Res. 2004 Aug;56(2):212-8. doi: 10.1203/01.PDR.0000132850.33375.D0. Epub 2004 Jun 4.
    Results Reference
    background
    PubMed Identifier
    15060200
    Citation
    Mone SM, Gillman MW, Miller TL, Herman EH, Lipshultz SE. Effects of environmental exposures on the cardiovascular system: prenatal period through adolescence. Pediatrics. 2004 Apr;113(4 Suppl):1058-69.
    Results Reference
    background
    PubMed Identifier
    14993536
    Citation
    Moore MM, Rifas-Shiman SL, Rich-Edwards JW, Kleinman KP, Camargo CA Jr, Gold DR, Weiss ST, Gillman MW. Perinatal predictors of atopic dermatitis occurring in the first six months of life. Pediatrics. 2004 Mar;113(3 Pt 1):468-74. doi: 10.1542/peds.113.3.468.
    Results Reference
    background
    PubMed Identifier
    14760269
    Citation
    Gillman MW, Rich-Edwards JW, Rifas-Shiman SL, Lieberman ES, Kleinman KP, Lipshultz SE. Maternal age and other predictors of newborn blood pressure. J Pediatr. 2004 Feb;144(2):240-5. doi: 10.1016/j.jpeds.2003.10.064.
    Results Reference
    background
    PubMed Identifier
    15492358
    Citation
    Taveras EM, Scanlon KS, Birch L, Rifas-Shiman SL, Rich-Edwards JW, Gillman MW. Association of breastfeeding with maternal control of infant feeding at age 1 year. Pediatrics. 2004 Nov;114(5):e577-83. doi: 10.1542/peds.2004-0801. Epub 2004 Oct 18.
    Results Reference
    background
    PubMed Identifier
    15466500
    Citation
    Oken E, Kleinman KP, Olsen SF, Rich-Edwards JW, Gillman MW. Associations of seafood and elongated n-3 fatty acid intake with fetal growth and length of gestation: results from a US pregnancy cohort. Am J Epidemiol. 2004 Oct 15;160(8):774-83. doi: 10.1093/aje/kwh282.
    Results Reference
    background
    PubMed Identifier
    15451777
    Citation
    Gillman MW, Rifas-Shiman SL, Kleinman KP, Rich-Edwards JW, Lipshultz SE. Maternal calcium intake and offspring blood pressure. Circulation. 2004 Oct 5;110(14):1990-5. doi: 10.1161/01.CIR.0000143199.93495.96. Epub 2004 Sep 27.
    Results Reference
    background
    PubMed Identifier
    15450130
    Citation
    Schaub B, Bellou A, Gibbons FK, Velasco G, Campo M, He H, Liang Y, Gillman MW, Gold D, Weiss ST, Perkins DL, Finn PW. TLR2 and TLR4 stimulation differentially induce cytokine secretion in human neonatal, adult, and murine mononuclear cells. J Interferon Cytokine Res. 2004 Sep;24(9):543-52. doi: 10.1089/jir.2004.24.543.
    Results Reference
    background
    PubMed Identifier
    15753269
    Citation
    Celi AC, Rich-Edwards JW, Richardson MK, Kleinman KP, Gillman MW. Immigration, race/ethnicity, and social and economic factors as predictors of breastfeeding initiation. Arch Pediatr Adolesc Med. 2005 Mar;159(3):255-60. doi: 10.1001/archpedi.159.3.255.
    Results Reference
    background

    Learn more about this trial

    Nutrition in Pregnancy, Birth Weight, and Childhood Asthma

    We'll reach out to this number within 24 hrs