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Observation of Young Patients Who Are Undergoing Surgery for Craniopharyngioma

Primary Purpose

Brain and Central Nervous System Tumors, Long-term Effects Secondary to Cancer Therapy in Children, Perioperative/Postoperative Complications

Status
Completed
Phase
Not Applicable
Locations
International
Study Type
Interventional
Intervention
metabolic assessment
physiologic testing
biopsy
computed tomography
conventional surgery
magnetic resonance imaging
management of therapy complications
psychosocial assessment and care
quality-of-life assessment
radiation therapy
Sponsored by
German Society for Pediatric Oncology and Hematology GPOH gGmbH
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional diagnostic trial for Brain and Central Nervous System Tumors focused on measuring psychosocial effects of cancer and its treatment, long-term effects secondary to cancer therapy in children, perioperative/postoperative complications, weight changes, childhood craniopharyngioma

Eligibility Criteria

undefined - 18 Years (Child, Adult)All SexesDoes not accept healthy volunteers

DISEASE CHARACTERISTICS: Diagnosis of primary craniopharyngioma by MRI and CT scan (initial diagnosis) Patients with only cystic sellar or parasellar malformation (e.g., Rathke pouch cysts or suprasellar cysts) are allowed but will undergo observation only PATIENT CHARACTERISTICS: Performance status Not specified Life expectancy Not specified Hematopoietic Not specified Hepatic Not specified Renal Not specified PRIOR CONCURRENT THERAPY: Not specified

Sites / Locations

  • Krankenhaus Dornbirn
  • Landeskrankenhaus Feldkirch
  • Universitaet Kinderklinik
  • Innsbruck Universitaetsklinik
  • Landeskrankenhaus Klagenfurt
  • LKH Leoben
  • A. oe. Krankenhaus der Barmherzigen Schwestern Kinderabteilung
  • Landes-Kinderkrankenhaus
  • St. Johanns-Spital
  • Kardinal Schwarzenbersches Krankenhaus Betriebsgesellschraft mbH Kinderspital
  • A. oe. Landeskrankenhaus Abt. fuer Kinderkrankheiten
  • St. Anna Children's Hospital
  • Allg. Krankenhaus der Stadt Wien Universitaets-Kinderklinik
  • Kinderklinik - Universitaetsklinikum Aachen
  • Klinikum Augsburg
  • Caritas-Krankenhaus Bad Mergentheim
  • Klinikum am Bamberg
  • Klinikum Bayreuth
  • Helios Klinikum Berlin
  • Charite - Campus Charite Mitte
  • Charite University Hospital - Campus Virchow Klinikum
  • Evangelisches Krankenhauus Bielfeld
  • Kinderklinik der Universitaet Bonn
  • Klinikum Bremen-Mitte
  • Allgemeinen Krankenhaus Celle Kinderklinik
  • Klinikum Chemnitz gGmbH
  • Klinikum Coburg
  • Kliniken der Stadt Koeln gGmbH - Kinderkrankenhaus Riehl
  • Children's Hospital
  • Carl - Thiem - Klinkum Cottbus
  • Vestische Kinderklinik Universitaetsklinik Witten/Herdecke
  • Klinikum Lippe - Detmold
  • Staedtisches Krankenhaus Dresden - Neustadt
  • Universitatsklinikum Carl Gustav Carus
  • Klinikum Duisburg
  • Klinikum Erfurt
  • Universitaets - Kinderklinik
  • Klinikum der J.W. Goethe Universitaet
  • Universitaetskinderklinik - Universitaetsklinikum Freiburg
  • Kinderklinik
  • Universitaetsklinikum Goettingen
  • Universitats - Kinderklinik
  • Kreiskrankenhaus Gummersbach GMBH
  • Universitaetsklinikum Halle
  • University Medical Center Hamburg - Eppendorf
  • Medizinische Hochschule Hannover
  • Universitaets-Kinderklinik Heidelberg
  • Kreskrankenhaus Kinderabteilung
  • SLK - Kliniken Heilbronn GmbH - Klinikum am Gesundbrunnen
  • Gemeinschaftskrankenhaus
  • Staedtisches Krankenhaus Hildesheim
  • Universitaetsklinikum des Saarlandes
  • Clinic for Bone Marrow Transplantation and Hematology and Oncology
  • Universitaets - Kinderklinik
  • Municipal Hospital Complex of the University
  • Staedtisches Klinikum Karlsruhe gGmbH
  • Klinikum Kassel
  • Staedtisches Krankenhaus Kiel
  • University Hospital Schleswig-Holstein - Kiel Campus
  • Klinikum Kemperhof Koblenz
  • Klinik Konstanz
  • Klinikum Krefeld GmbH
  • Kinderkrankenhaus St. Marien
  • Universitaets - Kinderklinik
  • St. Annastift Krankenhaus
  • Universitaets - Kinderklinik - Luebeck
  • Universitatsklinikum der MA
  • Johannes Gutenberg University
  • Staedtisches Klinik - Kinderklinik
  • Universitaets - Kinderklinik
  • Klinikum Minden
  • Krankenhaus Neuwerk Klinik fuer Kinder und Jugendmedizin
  • Klinik und Poliklinik fuer Kinder und Jugendmedizin - Universitaetsklinikum Muenster
  • Krankenhaus Muenchen Schwabing
  • Dr. von Haunersches Kinderspital der Universitaet Muenchen
  • Staedtisches Krankenhaus Muenchen - Harlaching
  • Klinikum Neubrandenburg
  • Lukaskrankenhaus Neuss
  • Marienhaus Klinikum St. Elisabeth Neuwied
  • Cnopf'sche Kinderklinik
  • Klinikum Nuernberg - Klinikum Sued
  • Klinikum Oldenburg
  • Marien Hospital
  • Paracelsus - Klinik Osnabrueck
  • Klinik St. Hedwig-Kinderklinik
  • Kinderklinik - Universitaetsklinikum Rostock
  • Saarbrucker Winterbergkliniken
  • Klinikum Schwerin
  • Kinderklink Siegen Deutsches Rotes Kreuz
  • Johanniter-Kinderklinik
  • Olgahospital
  • Krankenanstalt Mutterhaus der Borromaerinnen
  • Universitaetsklinikum Tuebingen
  • Comprehensive Cancer Center Ulm at Universitaetsklinikum Ulm
  • St. Marienhospital - Vechta
  • Staedtisches Klinikum - Howedestrase
  • Dr. Horst-Schmidt-Kliniken
  • Reinhard-Nieter-Krankenhaus
  • Klinikum der Stadt Wolfsburg
  • Universitaets - Kinderklinik Wuerzburg
  • Helios Kliniken Wuppertal University Hospital
  • Lanssjukhuset Ryhov
  • Kantonspital Aarau
  • Universitaets-Kinderspital beider Basel
  • Ospedale "la Carita", Locarno
  • Kinderspital Luzern
  • Ostschweizer Kinderspital
  • Kantonsspital Winterthur
  • University Children's Hospital

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

First Posted
November 22, 2005
Last Updated
August 1, 2013
Sponsor
German Society for Pediatric Oncology and Hematology GPOH gGmbH
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1. Study Identification

Unique Protocol Identification Number
NCT00258453
Brief Title
Observation of Young Patients Who Are Undergoing Surgery for Craniopharyngioma
Official Title
Prospective, Multi-Center Survey Study of Children and Adolescents With Craniopharyngioma
Study Type
Interventional

2. Study Status

Record Verification Date
October 2007
Overall Recruitment Status
Completed
Study Start Date
May 2001 (undefined)
Primary Completion Date
September 2007 (Actual)
Study Completion Date
September 2009 (Actual)

3. Sponsor/Collaborators

Name of the Sponsor
German Society for Pediatric Oncology and Hematology GPOH gGmbH

4. Oversight

5. Study Description

Brief Summary
RATIONALE: Collecting information on how craniopharyngioma is diagnosed and treated may help doctors predict a patient's response to treatment and help plan the best treatment. It may also help identify the intermediate- and long-term effects of treatment. PURPOSE: This clinical trial is collecting information on diagnosis, treatment, and quality of life of young patients who are undergoing surgery for craniopharyngioma.
Detailed Description
OBJECTIVES: Primary Identify all applied therapy strategies in pediatric patients with craniopharyngioma. Correlate relapse status with different therapy strategies/modality in these patients. Determine the health status (i.e., ophthalmologic, neuropediatric, and endocrine findings) and the health-related quality of life of these patients after treatment. Secondary Determine the incidence of craniopharyngioma in pediatric patients. Identify quality control measures for diagnosis and therapy in these patients. Improve long-term care through a standardized follow-up program in these patients. Determine the efficacy of endocrine substitution for postoperative hypopituitarism in these patients. Identify risk factors for developing obesity and correlate the neurotransmitter concentration of leptin and neuropeptide Y in cerebral spinal fluid, serum, and craniopharyngioma cystic fluid with the likelihood of developing obesity in these patients. Determine the incidence and extent of eating disorders in these patients. OUTLINE: This is a multicenter study. Patients undergo neurologic, endocrine, and ophthalmologic tests and anthropometric diagnostic measurements. Patients then undergo 1 of the following surgical procedures: total resection; incomplete, subtotal, or partial resection; biopsy; or cyst pressure release. Patients whose tumor relapses may undergo a second resection and/or radiotherapy. Quality of life is assessed at baseline and then periodically thereafter. After surgery, patients are followed periodically. PROJECTED ACCRUAL: A total of 120 patients will be accrued for this study.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Brain and Central Nervous System Tumors, Long-term Effects Secondary to Cancer Therapy in Children, Perioperative/Postoperative Complications, Psychosocial Effects of Cancer and Its Treatment, Weight Changes
Keywords
psychosocial effects of cancer and its treatment, long-term effects secondary to cancer therapy in children, perioperative/postoperative complications, weight changes, childhood craniopharyngioma

7. Study Design

Primary Purpose
Diagnostic
Study Phase
Not Applicable
Masking
None (Open Label)
Enrollment
120 (Anticipated)

8. Arms, Groups, and Interventions

Intervention Type
Other
Intervention Name(s)
metabolic assessment
Intervention Type
Other
Intervention Name(s)
physiologic testing
Intervention Type
Procedure
Intervention Name(s)
biopsy
Intervention Type
Procedure
Intervention Name(s)
computed tomography
Intervention Type
Procedure
Intervention Name(s)
conventional surgery
Intervention Type
Procedure
Intervention Name(s)
magnetic resonance imaging
Intervention Type
Procedure
Intervention Name(s)
management of therapy complications
Intervention Type
Procedure
Intervention Name(s)
psychosocial assessment and care
Intervention Type
Procedure
Intervention Name(s)
quality-of-life assessment
Intervention Type
Radiation
Intervention Name(s)
radiation therapy

10. Eligibility

Sex
All
Maximum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
DISEASE CHARACTERISTICS: Diagnosis of primary craniopharyngioma by MRI and CT scan (initial diagnosis) Patients with only cystic sellar or parasellar malformation (e.g., Rathke pouch cysts or suprasellar cysts) are allowed but will undergo observation only PATIENT CHARACTERISTICS: Performance status Not specified Life expectancy Not specified Hematopoietic Not specified Hepatic Not specified Renal Not specified PRIOR CONCURRENT THERAPY: Not specified
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Hermann Mueller, MD
Organizational Affiliation
Klinikum Oldenburg
Official's Role
Study Chair
Facility Information:
Facility Name
Krankenhaus Dornbirn
City
Dornbirn
ZIP/Postal Code
A-6850
Country
Austria
Facility Name
Landeskrankenhaus Feldkirch
City
Feldkirch-Tisis
ZIP/Postal Code
A-6807
Country
Austria
Facility Name
Universitaet Kinderklinik
City
Graz
ZIP/Postal Code
8036
Country
Austria
Facility Name
Innsbruck Universitaetsklinik
City
Innsbruck
ZIP/Postal Code
A-6020
Country
Austria
Facility Name
Landeskrankenhaus Klagenfurt
City
Klagenfurt
ZIP/Postal Code
9026
Country
Austria
Facility Name
LKH Leoben
City
Leoben
ZIP/Postal Code
A-8700
Country
Austria
Facility Name
A. oe. Krankenhaus der Barmherzigen Schwestern Kinderabteilung
City
Linz
ZIP/Postal Code
4010
Country
Austria
Facility Name
Landes-Kinderkrankenhaus
City
Linz
ZIP/Postal Code
A-4020
Country
Austria
Facility Name
St. Johanns-Spital
City
Salzburg
ZIP/Postal Code
A-5020
Country
Austria
Facility Name
Kardinal Schwarzenbersches Krankenhaus Betriebsgesellschraft mbH Kinderspital
City
Schwarzach
ZIP/Postal Code
5620
Country
Austria
Facility Name
A. oe. Landeskrankenhaus Abt. fuer Kinderkrankheiten
City
Steyr
ZIP/Postal Code
4400
Country
Austria
Facility Name
St. Anna Children's Hospital
City
Vienna
ZIP/Postal Code
A-1090
Country
Austria
Facility Name
Allg. Krankenhaus der Stadt Wien Universitaets-Kinderklinik
City
Wien
ZIP/Postal Code
1090
Country
Austria
Facility Name
Kinderklinik - Universitaetsklinikum Aachen
City
Aachen
ZIP/Postal Code
D-52074
Country
Germany
Facility Name
Klinikum Augsburg
City
Augsburg
ZIP/Postal Code
D-86156
Country
Germany
Facility Name
Caritas-Krankenhaus Bad Mergentheim
City
Bad Mergentheim
ZIP/Postal Code
D-97980
Country
Germany
Facility Name
Klinikum am Bamberg
City
Bamberg
ZIP/Postal Code
96049
Country
Germany
Facility Name
Klinikum Bayreuth
City
Bayreuth
ZIP/Postal Code
D-95445
Country
Germany
Facility Name
Helios Klinikum Berlin
City
Berlin
ZIP/Postal Code
13125
Country
Germany
Facility Name
Charite - Campus Charite Mitte
City
Berlin
ZIP/Postal Code
D-10117
Country
Germany
Facility Name
Charite University Hospital - Campus Virchow Klinikum
City
Berlin
ZIP/Postal Code
D-13353
Country
Germany
Facility Name
Evangelisches Krankenhauus Bielfeld
City
Biefeld
ZIP/Postal Code
33617
Country
Germany
Facility Name
Kinderklinik der Universitaet Bonn
City
Bonn
ZIP/Postal Code
D-53113
Country
Germany
Facility Name
Klinikum Bremen-Mitte
City
Bremen
ZIP/Postal Code
D-28205
Country
Germany
Facility Name
Allgemeinen Krankenhaus Celle Kinderklinik
City
Celle
ZIP/Postal Code
29223
Country
Germany
Facility Name
Klinikum Chemnitz gGmbH
City
Chemnitz
ZIP/Postal Code
D-09116
Country
Germany
Facility Name
Klinikum Coburg
City
Coburg
ZIP/Postal Code
96450
Country
Germany
Facility Name
Kliniken der Stadt Koeln gGmbH - Kinderkrankenhaus Riehl
City
Cologne
ZIP/Postal Code
D-50735
Country
Germany
Facility Name
Children's Hospital
City
Cologne
ZIP/Postal Code
D-50924
Country
Germany
Facility Name
Carl - Thiem - Klinkum Cottbus
City
Cottbus
ZIP/Postal Code
D-03048
Country
Germany
Facility Name
Vestische Kinderklinik Universitaetsklinik Witten/Herdecke
City
Datteln
ZIP/Postal Code
45711
Country
Germany
Facility Name
Klinikum Lippe - Detmold
City
Detmold
ZIP/Postal Code
D-32756
Country
Germany
Facility Name
Staedtisches Krankenhaus Dresden - Neustadt
City
Dresden
ZIP/Postal Code
D-01129
Country
Germany
Facility Name
Universitatsklinikum Carl Gustav Carus
City
Dresden
ZIP/Postal Code
D-01307
Country
Germany
Facility Name
Klinikum Duisburg
City
Duisburg
ZIP/Postal Code
D-47055
Country
Germany
Facility Name
Klinikum Erfurt
City
Erfurt
ZIP/Postal Code
99089
Country
Germany
Facility Name
Universitaets - Kinderklinik
City
Erlangen
ZIP/Postal Code
D-91054
Country
Germany
Facility Name
Klinikum der J.W. Goethe Universitaet
City
Frankfurt
ZIP/Postal Code
D-60590
Country
Germany
Facility Name
Universitaetskinderklinik - Universitaetsklinikum Freiburg
City
Freiburg
ZIP/Postal Code
D-79106
Country
Germany
Facility Name
Kinderklinik
City
Giessen
ZIP/Postal Code
D-35385
Country
Germany
Facility Name
Universitaetsklinikum Goettingen
City
Goettingen
ZIP/Postal Code
D-37075
Country
Germany
Facility Name
Universitats - Kinderklinik
City
Greiswald
ZIP/Postal Code
17487
Country
Germany
Facility Name
Kreiskrankenhaus Gummersbach GMBH
City
Gummersbach
ZIP/Postal Code
D-51643
Country
Germany
Facility Name
Universitaetsklinikum Halle
City
Halle
ZIP/Postal Code
D-06097
Country
Germany
Facility Name
University Medical Center Hamburg - Eppendorf
City
Hamburg
ZIP/Postal Code
D-20246
Country
Germany
Facility Name
Medizinische Hochschule Hannover
City
Hannover
ZIP/Postal Code
D-30625
Country
Germany
Facility Name
Universitaets-Kinderklinik Heidelberg
City
Heidelberg
ZIP/Postal Code
D-69120
Country
Germany
Facility Name
Kreskrankenhaus Kinderabteilung
City
Heide
ZIP/Postal Code
25746
Country
Germany
Facility Name
SLK - Kliniken Heilbronn GmbH - Klinikum am Gesundbrunnen
City
Heilbronn
ZIP/Postal Code
D-74064
Country
Germany
Facility Name
Gemeinschaftskrankenhaus
City
Herdecke
ZIP/Postal Code
58313
Country
Germany
Facility Name
Staedtisches Krankenhaus Hildesheim
City
Hildesheim
ZIP/Postal Code
D-31134
Country
Germany
Facility Name
Universitaetsklinikum des Saarlandes
City
Homburg
ZIP/Postal Code
66421
Country
Germany
Facility Name
Clinic for Bone Marrow Transplantation and Hematology and Oncology
City
Idar-Oberstein
ZIP/Postal Code
D-55743
Country
Germany
Facility Name
Universitaets - Kinderklinik
City
Jena
ZIP/Postal Code
D-07745
Country
Germany
Facility Name
Municipal Hospital Complex of the University
City
Kaiserslautern
ZIP/Postal Code
67655
Country
Germany
Facility Name
Staedtisches Klinikum Karlsruhe gGmbH
City
Karlsruhe
ZIP/Postal Code
76133
Country
Germany
Facility Name
Klinikum Kassel
City
Kassel
ZIP/Postal Code
D-34125
Country
Germany
Facility Name
Staedtisches Krankenhaus Kiel
City
Kiel
ZIP/Postal Code
23116
Country
Germany
Facility Name
University Hospital Schleswig-Holstein - Kiel Campus
City
Kiel
ZIP/Postal Code
D-24105
Country
Germany
Facility Name
Klinikum Kemperhof Koblenz
City
Koblenz
ZIP/Postal Code
D-56065
Country
Germany
Facility Name
Klinik Konstanz
City
Konstanz
ZIP/Postal Code
78461
Country
Germany
Facility Name
Klinikum Krefeld GmbH
City
Krefeld
ZIP/Postal Code
D-47805
Country
Germany
Facility Name
Kinderkrankenhaus St. Marien
City
Landshut
ZIP/Postal Code
84036
Country
Germany
Facility Name
Universitaets - Kinderklinik
City
Leipzig
ZIP/Postal Code
D-04317
Country
Germany
Facility Name
St. Annastift Krankenhaus
City
Ludwigshafen
ZIP/Postal Code
67065
Country
Germany
Facility Name
Universitaets - Kinderklinik - Luebeck
City
Luebeck
ZIP/Postal Code
D-23538
Country
Germany
Facility Name
Universitatsklinikum der MA
City
Magdeburg
ZIP/Postal Code
39112
Country
Germany
Facility Name
Johannes Gutenberg University
City
Mainz
ZIP/Postal Code
D-55131
Country
Germany
Facility Name
Staedtisches Klinik - Kinderklinik
City
Mannheim
ZIP/Postal Code
D-68167
Country
Germany
Facility Name
Universitaets - Kinderklinik
City
Marburg
ZIP/Postal Code
35033
Country
Germany
Facility Name
Klinikum Minden
City
Minden
ZIP/Postal Code
D-32423
Country
Germany
Facility Name
Krankenhaus Neuwerk Klinik fuer Kinder und Jugendmedizin
City
Moenchengladbach
ZIP/Postal Code
D-41066
Country
Germany
Facility Name
Klinik und Poliklinik fuer Kinder und Jugendmedizin - Universitaetsklinikum Muenster
City
Muenster
ZIP/Postal Code
D-48149
Country
Germany
Facility Name
Krankenhaus Muenchen Schwabing
City
Munich
ZIP/Postal Code
80804
Country
Germany
Facility Name
Dr. von Haunersches Kinderspital der Universitaet Muenchen
City
Munich
ZIP/Postal Code
D-80337
Country
Germany
Facility Name
Staedtisches Krankenhaus Muenchen - Harlaching
City
Munich
ZIP/Postal Code
D-81545
Country
Germany
Facility Name
Klinikum Neubrandenburg
City
Neubrandenburg
ZIP/Postal Code
17036
Country
Germany
Facility Name
Lukaskrankenhaus Neuss
City
Neuss
ZIP/Postal Code
D-41464
Country
Germany
Facility Name
Marienhaus Klinikum St. Elisabeth Neuwied
City
Neuwied
ZIP/Postal Code
56564
Country
Germany
Facility Name
Cnopf'sche Kinderklinik
City
Nuremberg
ZIP/Postal Code
90419
Country
Germany
Facility Name
Klinikum Nuernberg - Klinikum Sued
City
Nuremberg
ZIP/Postal Code
D-90471
Country
Germany
Facility Name
Klinikum Oldenburg
City
Oldenburg
ZIP/Postal Code
26133
Country
Germany
Facility Name
Marien Hospital
City
Osnabruck
ZIP/Postal Code
D-49074
Country
Germany
Facility Name
Paracelsus - Klinik Osnabrueck
City
Osnabrueck
ZIP/Postal Code
D-49076
Country
Germany
Facility Name
Klinik St. Hedwig-Kinderklinik
City
Regensburg
ZIP/Postal Code
93049
Country
Germany
Facility Name
Kinderklinik - Universitaetsklinikum Rostock
City
Rostock
ZIP/Postal Code
D-18057
Country
Germany
Facility Name
Saarbrucker Winterbergkliniken
City
Saarbrucken
ZIP/Postal Code
66119
Country
Germany
Facility Name
Klinikum Schwerin
City
Schwerin
ZIP/Postal Code
D-19049
Country
Germany
Facility Name
Kinderklink Siegen Deutsches Rotes Kreuz
City
Siegen
ZIP/Postal Code
D-57072
Country
Germany
Facility Name
Johanniter-Kinderklinik
City
St. Augustin
ZIP/Postal Code
53757
Country
Germany
Facility Name
Olgahospital
City
Stuttgart
ZIP/Postal Code
D-70176
Country
Germany
Facility Name
Krankenanstalt Mutterhaus der Borromaerinnen
City
Trier
ZIP/Postal Code
D-54290
Country
Germany
Facility Name
Universitaetsklinikum Tuebingen
City
Tuebingen
ZIP/Postal Code
D-72076
Country
Germany
Facility Name
Comprehensive Cancer Center Ulm at Universitaetsklinikum Ulm
City
Ulm
ZIP/Postal Code
D-89075
Country
Germany
Facility Name
St. Marienhospital - Vechta
City
Vechta
ZIP/Postal Code
D-49377
Country
Germany
Facility Name
Staedtisches Klinikum - Howedestrase
City
Vechta
ZIP/Postal Code
D-49377
Country
Germany
Facility Name
Dr. Horst-Schmidt-Kliniken
City
Wiesbaden
ZIP/Postal Code
D-65199
Country
Germany
Facility Name
Reinhard-Nieter-Krankenhaus
City
Wilhelmshaven
ZIP/Postal Code
D-26389
Country
Germany
Facility Name
Klinikum der Stadt Wolfsburg
City
Wolfsburg
ZIP/Postal Code
D-38440
Country
Germany
Facility Name
Universitaets - Kinderklinik Wuerzburg
City
Wuerzburg
ZIP/Postal Code
D-97080
Country
Germany
Facility Name
Helios Kliniken Wuppertal University Hospital
City
Wuppertal
ZIP/Postal Code
D-42283
Country
Germany
Facility Name
Lanssjukhuset Ryhov
City
Jonkoping
ZIP/Postal Code
S-55185
Country
Sweden
Facility Name
Kantonspital Aarau
City
Aarau
ZIP/Postal Code
CH-5001
Country
Switzerland
Facility Name
Universitaets-Kinderspital beider Basel
City
Basel
ZIP/Postal Code
CH-4005
Country
Switzerland
Facility Name
Ospedale "la Carita", Locarno
City
Locarno
ZIP/Postal Code
6600
Country
Switzerland
Facility Name
Kinderspital Luzern
City
Lucerne 16
ZIP/Postal Code
CH-6000
Country
Switzerland
Facility Name
Ostschweizer Kinderspital
City
St. Gallen
ZIP/Postal Code
9006
Country
Switzerland
Facility Name
Kantonsspital Winterthur
City
Winterthur
ZIP/Postal Code
CH-8400
Country
Switzerland
Facility Name
University Children's Hospital
City
Zurich
ZIP/Postal Code
CH-8032
Country
Switzerland

12. IPD Sharing Statement

Citations:
PubMed Identifier
20379145
Citation
Roth CL, Gebhardt U, Muller HL. Appetite-regulating hormone changes in patients with craniopharyngioma. Obesity (Silver Spring). 2011 Jan;19(1):36-42. doi: 10.1038/oby.2010.80. Epub 2010 Apr 8.
Results Reference
result
PubMed Identifier
20197669
Citation
Muller HL, Gebhardt U, Schroder S, Pohl F, Kortmann RD, Faldum A, Zwiener I, Warmuth-Metz M, Pietsch T, Calaminus G, Kolb R, Wiegand C, Sorensen N; study committee of KRANIOPHARYNGEOM 2000/2007. Analyses of treatment variables for patients with childhood craniopharyngioma--results of the multicenter prospective trial KRANIOPHARYNGEOM 2000 after three years of follow-up. Horm Res Paediatr. 2010;73(3):175-80. doi: 10.1159/000284358. Epub 2010 Mar 3.
Results Reference
result
PubMed Identifier
29971569
Citation
Mehren A, Ozyurt J, Zu Klampen P, Boekhoff S, Thiel CM, Muller HL. Self- and informant-rated apathy in patients with childhood-onset craniopharyngioma. J Neurooncol. 2018 Oct;140(1):27-35. doi: 10.1007/s11060-018-2936-z. Epub 2018 Jul 3.
Results Reference
derived
PubMed Identifier
28259055
Citation
Ozyurt J, Muller HL, Warmuth-Metz M, Thiel CM. Hypothalamic tumors impact gray and white matter volumes in fronto-limbic brain areas. Cortex. 2017 Apr;89:98-110. doi: 10.1016/j.cortex.2017.01.017. Epub 2017 Feb 3.
Results Reference
derived
PubMed Identifier
27585663
Citation
Daubenbuchel AM, Hoffmann A, Eveslage M, Ozyurt J, Lohle K, Reichel J, Thiel CM, Martens H, Geenen V, Muller HL. Oxytocin in survivors of childhood-onset craniopharyngioma. Endocrine. 2016 Nov;54(2):524-531. doi: 10.1007/s12020-016-1084-5. Epub 2016 Sep 1.
Results Reference
derived
PubMed Identifier
27125511
Citation
Hoffmann A, Warmuth-Metz M, Lohle K, Reichel J, Daubenbuchel AM, Sterkenburg AS, Muller HL. Fusiform dilatation of the internal carotid artery in childhood-onset craniopharyngioma: multicenter study on incidence and long-term outcome. Pituitary. 2016 Aug;19(4):422-8. doi: 10.1007/s11102-016-0722-5.
Results Reference
derived
PubMed Identifier
24507865
Citation
Ozyurt J, Thiel CM, Lorenzen A, Gebhardt U, Calaminus G, Warmuth-Metz M, Muller HL. Neuropsychological outcome in patients with childhood craniopharyngioma and hypothalamic involvement. J Pediatr. 2014 Apr;164(4):876-881.e4. doi: 10.1016/j.jpeds.2013.12.010. Epub 2014 Feb 6.
Results Reference
derived
PubMed Identifier
19766264
Citation
Roth CL, Enriori PJ, Gebhardt U, Hinney A, Muller HL, Hebebrand J, Reinehr T, Cowley MA. Changes of peripheral alpha-melanocyte-stimulating hormone in childhood obesity. Metabolism. 2010 Feb;59(2):186-94. doi: 10.1016/j.metabol.2009.06.031. Epub 2009 Sep 18.
Results Reference
derived

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Observation of Young Patients Who Are Undergoing Surgery for Craniopharyngioma

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