Obstructive Sleep Apnea and Comprehensive Remotely-supervised Rehabilitation Program

The purpose of this study is to investigate the feasibility and effect of a 12-week remotely-supervised rehabilitation program in male patients between 25-65 years old with newly diagnosed obstructive sleep apnea with Apnea-Hypopnea Index greater than 15 episodes per hour indicated to CPAP therapy.

The intervention group will undergo comprehensive remotely-supervised rehabilitaiton program in home conditions with teleconsultation (contains telecoaching, telemonitoring) via regular phone calls and e-mails at least 2 times a week. The intervention will include nutrition, health-related lifestyle and behavioral changes recommendations, and at least 5 times a week 30 minutes of moderate-intensity aerobic training, 10 minutes of inspiratory and expiratory muscle training with breathing device and 10 minutes of oropharyngeal exercise along with individually titrated CPAP therapy. The control group will undergo individually titrated CPAP therapy only. The participants in both groups will go through the following assessments before and after this study: polysomnography, spirometry, anthropometry and body composition examination, laboratory values examination, quality of life questionnaires, Epworth sleepiness scale, 6-min walking test.

Remotely-supervised rehabilitation program, Apnea-Hypopnea Index, Telemonitoring, Telecoaching, Telerehabilitation, CPAP

Participants will undergo 12-week comprehensive remotely-supervised rehabilitation program along with individually titrated CPAP therapy.

Include nutrition, health-related lifestyle and behavioral changes recommendations, and at least 5 times a week 30 minutes of moderate-intensity aerobic training, 10 minutes of inspiratory and expiratory muscle training with breathing device and 10 minutes of oropharyngeal exercise along with individually titrated CPAP therapy

Measure will be taken from Polysomnography. Index shows number of apneic or hypopneic periods with duration at least 5 seconds in one hour. Higher Index means worse outcome.

ESS Score is validated, self-reported instrument of patient's perception of obstructive sleep apnea. Possible scores range is from 0 to 24 points. Higher score means worse outcome.

SF-36 Score is validated, self-reported instrument of patient's perception of health state and quality of life. Possible scores range is from 0 to 100 points. Higher score means better outcome.

6MWT will be evaluated on flat 30 metres long track marked with two cones. Longer distance means better outcome.

Participants will make 3-5 attempts with 1 minute pause between them. Noted will be the highest score. Higher score means better outcome.

Participants will make 3-5 attempts with 1 minute pause between them. Noted will be the highest score. Higher score means better outcome.

Measure will be taken from Polysomnography. ODI means number of times per hour of sleep that the blood's oxygen level drop by a certain degree from baseline.

Inclusion Criteria: signed informed consent newly diagnosed obstructive sleep apnea Apnea-Hypopnea Index greater than 15 episodes/hour indicated for CPAP therapy Exclusion Criteria: severe pulmonary hypertension severe heart valve disease COPD III or IV central sleep apnea chronic corticosteroid therapy long-term oxygen therapy heart failure left ventricular ejection fraction lower than 40 % NYHA III or IV cerebrovascular disease psychiatric disease another type of obstructive sleep apnea treatment acute coronary syndrome in anamnesis