Open-Label Pilot Study of the Efficacy and Safety of Vusion Ointment for the Treatment of Intertrigo

The purpose of this study is to determine if people with moist, red, patches on their skin in body folds would benefit treatment of those areas with an FDA-approved drug called Vusion.

Intertrigo is an inflammatory condition of skin folds, induced or aggravated by heat, moisture, maceration, friction, or lack of air circulation. It is typically chronic with insidious onset of itching, burning, and stinging within the affected skin folds. Intertrigo frequently worsened or colonized by infection, which most commonly is candidal but also may be bacterial, fungal, or viral. The etiology of diaper dermatitis shows significant overlap with that of intertrigo. Vusion ointment, a highly effective treatment for diaper dermatitis, has been used by physicians for the treatment of intertrigo; however, there is a paucity of data in the literature regarding the use of Vusion ointment in this indication. This study is the first to formally investigate the efficacy and safety of Vusion ointment for the treatment of intertrigo.

Inclusion Criteria: Evidence of intertrigo Exclusion Criteria: Pregnancy Use of systemic or topical antifungal or corticosteroid treatment in the previous 14 days or during the 3-month treatment period allergy of sensitivity to Vusion undergoing warfarin anticoagulation alcohol or drug abuse Investigator determines they cannot particpate history of non-compliance or poor cooperation participation in an investigaitonal drug study within 30 days of Baseline Visit