Optimising Community Antibiotic Use and Infection Control With Behavioural Interventions in Burkina Faso and DR Congo (CABU-B/C)
Antimicrobial Stewardship, Drug Resistance, Bacterial
About this trial
This is an interventional prevention trial for Antimicrobial Stewardship focused on measuring behavioural intervention, sub-Sahara Africa, rodent surveillance, health demographic surveillance sites, Anti-Bacterial Agents / therapeutic use
Eligibility Criteria
Patient exit surveys
Inclusion Criteria:
- Visitor to a medicine dispenser for his/her own health or that of someone else, regardless of disease or age
- Having just completed a visit to a medicine dispenser in a study cluster who agreed to participate in the study Exclusion Criteria: none
Simulated patient visits (dispensers)
Inclusion criteria:
- Prescribe or dispense medicines in a community pharmacy, medicine store, or other private clinic or outlet within the selected study clusters;
- Consented at the start of the study to participate in the intervention bundle evaluation Exclusion Criteria: none
Faecal Enterobacteriaceae carriage and transmission (members of selected households) and household surveys (household heads) Inclusion criteria
- Member of a household in a study cluster (resident for >/= 3 months);
- Agreement of the household head for all household members (including children) to participate to the collection of four stool samples during the study period, through informed written consent;
- Individual informed consent (plus assent for adolescent participants) for each participating household member;
- be in good physical health (no current infectious disease); Exclusion criteria
- Inhabitant of study clusters who planned to move or be absent during the following year;
- Temporary exclusion: Ongoing infectious disease or ongoing treatment for an infectious disease. Field workers will return to collect stools once the patient has recovered
Sites / Locations
- Clinical Research Unit of Nanoro (CRUN)
- Centre de Recherche en Santé de Kimpese (CRSK)
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Intervention clusters
Control clusters
Intervention bundle consisting of 3 components introduced over 12 months: one to improve antibiotic use targeting health centres and medicine stores and two targeting the general population: one to increase community health literacy and one to improve water, hygiene and sanitation practices.