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Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain

Primary Purpose

Acute Coronary Syndromes

Status
Completed
Phase
Phase 4
Locations
Sweden
Study Type
Interventional
Intervention
Metoprolol
metoprolol plus morphine
Sponsored by
Sahlgrenska University Hospital, Sweden
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional trial for Acute Coronary Syndromes focused on measuring Acute coronary syndrome, Chest pain, Betablockers, Morphine, Prehospital phase

Eligibility Criteria

undefined - undefined (Child, Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Acute chest pain
  • ECG-signs indicating myocardial ischemia

Exclusion Criteria:

  • Heart rate < 60 beats/min
  • Systolic blood pressure < 110 mmHg
  • High degree AV-block
  • Signs of obstructive pulmonary disease
  • Signs of pulmonary oedema
  • Unwillingness
  • Participation in other studies
  • Long delay between arrival of ambulance and randomisation

Sites / Locations

  • Medical Institution, Dept of Molecular and Clinical Medicine, Sahlgrenska University Hospital

Arms of the Study

Arm 1

Arm 2

Arm Type

Active Comparator

Active Comparator

Arm Label

A

B

Arm Description

A=metoprolol

B=metoprolol plus morphine

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

First Posted
July 16, 2008
Last Updated
July 16, 2008
Sponsor
Sahlgrenska University Hospital, Sweden
Collaborators
AstraZeneca
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1. Study Identification

Unique Protocol Identification Number
NCT00718406
Brief Title
Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain
Study Type
Interventional

2. Study Status

Record Verification Date
August 2002
Overall Recruitment Status
Completed
Study Start Date
undefined (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
undefined (undefined)

3. Sponsor/Collaborators

Name of the Sponsor
Sahlgrenska University Hospital, Sweden
Collaborators
AstraZeneca

4. Oversight

5. Study Description

Brief Summary
The primary aim was to evaluate the relief of chest pain during the first 30 minutes among patients who received metoprolol alone as compared with metoprolol plus morphine

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Acute Coronary Syndromes
Keywords
Acute coronary syndrome, Chest pain, Betablockers, Morphine, Prehospital phase

7. Study Design

Study Phase
Phase 4

8. Arms, Groups, and Interventions

Arm Title
A
Arm Type
Active Comparator
Arm Description
A=metoprolol
Arm Title
B
Arm Type
Active Comparator
Arm Description
B=metoprolol plus morphine
Intervention Type
Drug
Intervention Name(s)
Metoprolol
Intervention Type
Drug
Intervention Name(s)
metoprolol plus morphine

10. Eligibility

Sex
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Acute chest pain ECG-signs indicating myocardial ischemia Exclusion Criteria: Heart rate < 60 beats/min Systolic blood pressure < 110 mmHg High degree AV-block Signs of obstructive pulmonary disease Signs of pulmonary oedema Unwillingness Participation in other studies Long delay between arrival of ambulance and randomisation
Facility Information:
Facility Name
Medical Institution, Dept of Molecular and Clinical Medicine, Sahlgrenska University Hospital
City
Göteborg
ZIP/Postal Code
SE-413 45
Country
Sweden

12. IPD Sharing Statement

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Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain

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