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Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- UCLA Portal R/R Influenza RCT 3

Primary Purpose

Influenza, Respiratory Tract Infections

Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Portal Reminders for Influenza Vaccination: Direct scheduling link
Portal Reminders for Influenza Vaccination: No direct scheduling link
Pre-Commitment Prompt
Pre-Appointment flu vaccine reminders
Sponsored by
University of California, Los Angeles
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional health services research trial for Influenza focused on measuring Vaccination, Reminder recall, Patient Portal

Eligibility Criteria

4 Months - undefined (Child, Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

A patient within the UCLA Health System identified as a primary care patient per an internal algorithm.

Exclusion Criteria:

A patient within the UCLA Health System not identified as a primary care patient per an internal algorithm

Sites / Locations

  • University of California LA

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm 5

Arm 6

Arm 7

Arm 8

Arm 9

Arm Type

Active Comparator

Active Comparator

Active Comparator

Active Comparator

Active Comparator

Active Comparator

Active Comparator

Active Comparator

No Intervention

Arm Label

Direct scheduling + Pre-commitment + Pre-appt reminder

Direct scheduling + Pre-commitment

Direct scheduling + Pre-appt reminder

Direct scheduling

No direct scheduling + Pre-commitment + Pre-Appt reminder

No direct scheduling + Pre-commitment

No direct scheduling + Pre-appt reminder

No direct scheduling

Control Arm

Arm Description

Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal with a link enabling direct scheduling, 2) a pre-commitment prompt and 3) pre-appointment reminders that mention asking the provider for a flu vaccine

Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal with a link enabling direct scheduling and 2) a pre-commitment prompt

Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal with a link enabling direct scheduling and 2) pre-appointment reminders that mention asking the provider for a flu vaccine

Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal with a link enabling direct scheduling

Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal without a link enabling direct scheduling, 2) a pre-commitment prompt and 3) pre-appointment reminders that mention asking the provider for a flu vaccine

Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal without a link enabling direct scheduling and 2) a pre-commitment prompt

Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal without a link enabling direct scheduling and 2) pre-appointment reminders that mention asking the provider for a flu vaccine

Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal without a link enabling direct scheduling for a flu vaccine appointment

Participants will not receive any reminder/recall messages regarding influenza vaccination via the patient portal or other intervention components

Outcomes

Primary Outcome Measures

Number of Index Patients Who Received Annual Influenza Vaccine
Receipt of the annual influenza vaccination (between 8/1/20 - 4/1/21) among index patients. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data. The index patients must also be an active UCLA Health MyChart user (>= 1 login over the last 12 months from 8/1/20, excluding activity on the user's initial profile activation date). Individuals not affiliated with any primary care practice will be excluded from the primary analysis.

Secondary Outcome Measures

Full Information

First Posted
August 26, 2020
Last Updated
October 1, 2022
Sponsor
University of California, Los Angeles
Collaborators
National Institute of Allergy and Infectious Diseases (NIAID)
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1. Study Identification

Unique Protocol Identification Number
NCT04533685
Brief Title
Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- UCLA Portal R/R Influenza RCT 3
Official Title
Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- RCT 3
Study Type
Interventional

2. Study Status

Record Verification Date
October 2022
Overall Recruitment Status
Completed
Study Start Date
September 1, 2020 (Actual)
Primary Completion Date
April 1, 2021 (Actual)
Study Completion Date
April 1, 2021 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of California, Los Angeles
Collaborators
National Institute of Allergy and Infectious Diseases (NIAID)

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
This trial is taking place in Los Angeles, CA among patients from primary care practices within the UCLA Health System. The study design is a 2x2x2 factorial design, nested in a parallel 2-arm trial. The parallel arms are control v. reminder letter (reminder messages sent via the patient portal, reminding participants of an overdue influenza vaccine) Nested within the reminder letter arm, we will have 3 additional components: A direct scheduling link within the reminder letter enabling the patient to schedule an influenza vaccine only visit (direct scheduling link vs. no direct scheduling link). A pre-commitment prompt (pre-commitment prompt vs. no prompt) asking about a patient's intention to get the influenza vaccination A pre-appointment reminder, encouraging patients to ask for their influenza vaccine at their upcoming appointment (pre-appointment reminder encouraging influenza vaccination vs. standard pre-appointment reminder not mentioning influenza vaccination)
Detailed Description
This trial is taking place in Los Angeles, CA among patients from primary care practices within the UCLA Health System, using 2x2x2 factorial design, nested in a parallel 2-arm trial. Sub-optimal vaccination rates are a significant problem in the U.S., despite their effectiveness in preventing morbidity and mortality from vaccine-preventable illness. For influenza specifically, annual epidemics of influenza cause substantial morbidity in the U.S. with up to 40,00-80,000 deaths/year and many hospitalizations, emergency and outpatient visits, and significant costs. Reminder/recall (R/R) messages, sent by phone, mail or other modality, can improve child and adult influenza vaccination rates. However, the majority of pediatric or adult primary care practices to not conduct R/R. Barriers are lack of finances, personnel, and algorithms to identify eligible patients. A technological breakthrough that might overcome these barriers involves patient portals-- secure, web-based communication systems, embedded within electronic health records (EHRs), for patients and providers to communicate with each other via email and the internet. Portals are used by about half of Americans and half of UCLA patients. This randomized controlled trial will assess the effectiveness of reminders messages, encouraging influenza vaccination, sent to patient portal users on increasing influenza vaccination rates within a health system by randomizing patients to two groups: 1) two-thirds of patients will receive reminder letters, 2) one-third will not receive reminders. Patients in the reminder arm will be further randomized (separately) for three additional components: 1) direct appointment scheduling, 2) pre-commitment prompts and 3) pre-appointment reminders. Direct scheduling: The convenience of scheduling an appointment for influenza vaccination may increase the likelihood that patients receive an influenza vaccination. Patients receiving reminders will be randomized to receive one of two types of reminder letters: 1) one half will receive flu vaccine reminder letters with a link to the MyChart direct appointment scheduling page and 2) one half will receive flu vaccine reminder message without the direct appointment scheduling link. Pre-commitment: Another potential influence on the decision to vaccinate is pre-commitment. Previous studies suggest that, upon being prompted, indicating an intention to do something increases the likelihood of following through. Patients will be randomized to one of two groups: 1) one half will receive pre-commitment prompt at the beginning of influenza vaccination season and 2) one half will not receive a pre-commitment prompt. The pre-commitment prompt asks whether the patient intends to receive influenza vaccine, and where and when they plan to get the vaccine. Pre-appointment flu reminders: Finally, a missed opportunities for vaccination occurs when patients are eligible for vaccination but are not offered a vaccine at their medical appointment. Pre-appointment reminders, sent in advance of an upcoming appointment, encouraging the patient talk to their doctor about influenza vaccination, may increase the likelihood of that patient receiving a vaccine. Patients will be randomized to one of two groups: 1) one half will receive modified pre-appointment reminders that mention influenza vaccination and 2) one half will receive the standard pre-appointment reminders for an upcoming appointment (no mention of influenza vaccination).

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Influenza, Respiratory Tract Infections
Keywords
Vaccination, Reminder recall, Patient Portal

7. Study Design

Primary Purpose
Health Services Research
Study Phase
Not Applicable
Interventional Study Model
Factorial Assignment
Model Description
A 2x2x2 factorial design, nested within a parallel 2-arm trial.
Masking
Participant
Allocation
Randomized
Enrollment
213773 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Direct scheduling + Pre-commitment + Pre-appt reminder
Arm Type
Active Comparator
Arm Description
Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal with a link enabling direct scheduling, 2) a pre-commitment prompt and 3) pre-appointment reminders that mention asking the provider for a flu vaccine
Arm Title
Direct scheduling + Pre-commitment
Arm Type
Active Comparator
Arm Description
Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal with a link enabling direct scheduling and 2) a pre-commitment prompt
Arm Title
Direct scheduling + Pre-appt reminder
Arm Type
Active Comparator
Arm Description
Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal with a link enabling direct scheduling and 2) pre-appointment reminders that mention asking the provider for a flu vaccine
Arm Title
Direct scheduling
Arm Type
Active Comparator
Arm Description
Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal with a link enabling direct scheduling
Arm Title
No direct scheduling + Pre-commitment + Pre-Appt reminder
Arm Type
Active Comparator
Arm Description
Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal without a link enabling direct scheduling, 2) a pre-commitment prompt and 3) pre-appointment reminders that mention asking the provider for a flu vaccine
Arm Title
No direct scheduling + Pre-commitment
Arm Type
Active Comparator
Arm Description
Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal without a link enabling direct scheduling and 2) a pre-commitment prompt
Arm Title
No direct scheduling + Pre-appt reminder
Arm Type
Active Comparator
Arm Description
Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal without a link enabling direct scheduling and 2) pre-appointment reminders that mention asking the provider for a flu vaccine
Arm Title
No direct scheduling
Arm Type
Active Comparator
Arm Description
Participants receive 1) reminder/recall messages regarding influenza vaccination via the patient portal without a link enabling direct scheduling for a flu vaccine appointment
Arm Title
Control Arm
Arm Type
No Intervention
Arm Description
Participants will not receive any reminder/recall messages regarding influenza vaccination via the patient portal or other intervention components
Intervention Type
Behavioral
Intervention Name(s)
Portal Reminders for Influenza Vaccination: Direct scheduling link
Intervention Description
Patients receive reminder/recall messages via the patient portal to get an influenza vaccination that include a direct scheduling link, enabling the patient to directly schedule a flu vaccination only visit
Intervention Type
Behavioral
Intervention Name(s)
Portal Reminders for Influenza Vaccination: No direct scheduling link
Intervention Description
Patients receive reminder/recall messages via the patient portal to get an influenza vaccination (no direct scheduling link included)
Intervention Type
Behavioral
Intervention Name(s)
Pre-Commitment Prompt
Intervention Description
Patients receive a pre-commitment prompt asking about their intention to get an influenza vaccination
Intervention Type
Behavioral
Intervention Name(s)
Pre-Appointment flu vaccine reminders
Intervention Description
Patients receive modified pre-appointment reminders for upcoming scheduled appointments that include language encouraging patients to ask the provider for the flu vaccine
Primary Outcome Measure Information:
Title
Number of Index Patients Who Received Annual Influenza Vaccine
Description
Receipt of the annual influenza vaccination (between 8/1/20 - 4/1/21) among index patients. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data. The index patients must also be an active UCLA Health MyChart user (>= 1 login over the last 12 months from 8/1/20, excluding activity on the user's initial profile activation date). Individuals not affiliated with any primary care practice will be excluded from the primary analysis.
Time Frame
6 months

10. Eligibility

Sex
All
Minimum Age & Unit of Time
4 Months
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: A patient within the UCLA Health System identified as a primary care patient per an internal algorithm. Exclusion Criteria: A patient within the UCLA Health System not identified as a primary care patient per an internal algorithm
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Peter G Szilagyi, MD, MPH
Organizational Affiliation
Professor of Pediatrics
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of California LA
City
Los Angeles
State/Province
California
ZIP/Postal Code
99095
Country
United States

12. IPD Sharing Statement

Learn more about this trial

Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- UCLA Portal R/R Influenza RCT 3

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