Patient Preference for Mouthpiece Ventilation
Neuromuscular Diseases
About this trial
This is an interventional treatment trial for Neuromuscular Diseases focused on measuring noninvasive ventilation
Eligibility Criteria
Inclusion Criteria:
- All individuals affected by NMDs attending our Centre for Home Mechanical Ventilation between January 2015 and December 2018 who required daytime MPV as an extension of nocturnal NIV
Exclusion Criteria:
- Patients with no need for daytime ventilation
- patients with ineffective NIV during sleep as assessed by the measurement of TcCO2>49mmHg (S)
- patients with uncontrollable oral leaks with MPV or episode of acute respiratory infection during the trials
Sites / Locations
- Michel Toussaint
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Ventilator PB560 (Covidien)
Ventilator Trilogy (Philips Respironics)
The non-dedicated (NON-DED) set comprised a ventilator for MPV (PB560) using a single active tubing with an exhalation valve. A custom-made arm support and plastic mouthpiece were used.
The dedicated (DED) set comprised a ventilator for MPV (Trilogy 100, Philips Respironics; with dedicated software, with a single passive tubing without exhalation valve. A back-up rate set at zero cycle per minute was associated with a kiss trigger, with a smart flexible tube support system and with a silicone made mouthpiece designed as a straw.