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Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.

Primary Purpose

Spinal Cord Injury, Degenerative Spinal Disease.

Status

Completed

Phase

Not Applicable

Locations

Taiwan

Study Type

Interventional

Intervention

imaging diagnostics

About this trial

This is an interventional diagnostic trial for Spinal Cord Injury, Degenerative Spinal Disease.

Eligibility Criteria

20 Years - 80 Years (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

Patients with a diagnosis of spinal cord injury and degenerative spinal disease
Normal volunteers

Exclusion Criteria:

- Patients with cancer and infection.

Sites / Locations

Tiffany Ting-Fang Shih

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

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Arm Description

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Outcomes

Primary Outcome Measures

Disc Perfusion

Secondary Outcome Measures

Full Information

NCT ID

NCT01973257

First Posted

October 24, 2013

Last Updated

October 31, 2013

Sponsor

National Taiwan University Hospital

1. Study Identification

Unique Protocol Identification Number

NCT01973257

Brief Title

Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.

Official Title

Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.

Study Type

Interventional

2. Study Status

Record Verification Date

October 2013

Overall Recruitment Status

Completed

Study Start Date

August 2007 (undefined)

Primary Completion Date

July 2010 (Actual)

Study Completion Date

July 2010 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

National Taiwan University Hospital

4. Oversight

5. Study Description

Brief Summary

The purpose of our study is to evaluate the perfusion of the IVDs and their diffusion ability by using the Dynamic contrast-enhanced MR perfusion technique and Diffusion weighted image with ADC value measurement, and to determine the relationship between these data and the degeneration of IVDs, the different posture, and different stress-loading status.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Spinal Cord Injury, Degenerative Spinal Disease.

7. Study Design

Primary Purpose

Diagnostic

Study Phase

Not Applicable

Interventional Study Model

Parallel Assignment

Masking

Participant

Enrollment

50 (Actual)

8. Arms, Groups, and Interventions

Arm Title

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Arm Type

Experimental

Arm Description

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Intervention Type

Procedure

Intervention Name(s)

imaging diagnostics

Primary Outcome Measure Information:

Title

Disc Perfusion

Time Frame

3 months

10. Eligibility

Sex

All

Minimum Age & Unit of Time

20 Years

Maximum Age & Unit of Time

80 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: Patients with a diagnosis of spinal cord injury and degenerative spinal disease Normal volunteers Exclusion Criteria: - Patients with cancer and infection.

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Tiffany Ting-Fang Shih

Organizational Affiliation

Department of Medical Image, National Taiwan University Hospital

Official's Role

Principal Investigator

Facility Information:

Facility Name

Tiffany Ting-Fang Shih

City

Taipei

ZIP/Postal Code

100

Country

Taiwan

12. IPD Sharing Statement

Learn more about this trial

Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.

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