Peri-Operative Lidocane, Ketamine, or Lidocane and Ketamine Combination, Infusion for Patients Undergoing Spine Surgery
Postoperative Pain
About this trial
This is an interventional treatment trial for Postoperative Pain
Eligibility Criteria
Inclusion Criteria:
Male and Female >/= 18 years of age Patients undergoing first-time fusion surgery or surgery to revise a prior fusion Able to read, write and speak in English, and able to give informed consent for the study
Exclusion Criteria:
Any disease associated with major organ dysfunction renal dysfunction hepatic dysfunction cardiac dysfunction
Sites / Locations
- Beth Israel Medical Center
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Placebo Comparator
Ketamine
Lidocaine
Ketamine and Lidocaine
Placebo
Ketamine infused at 0.25 mg/kg/hour.
Lidocaine infused at 0.5 mg/kg/hour.
Ketamine infused at 0.25 mg/kg/hour along with lidocaine at 0.5 mg/kg/hour
Placebo (saline) given to compare usual treatment against active agents in post operative pain management.