search
Back to results

Pericapsular Nerve Group Block Versus Lumber Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty

Primary Purpose

Post Operative Pain, Chronic

Status
Not yet recruiting
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
PENG block
lumbar erector spinae plane block
Sponsored by
Assiut University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional prevention trial for Post Operative Pain, Chronic

Eligibility Criteria

18 Years - 80 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  1. ASA grade 1&2 &3
  2. Adult patients (Age >18 yrs)
  3. Eligible patients were aged 18 years or older, were admitted for hip arthroplasty (THA or HA) for femoral neck fracture, and had undergone a preoperative RA technique (PENG block or lumbar erector spinae plane block)

Exclusion Criteria:

  1. Patients with chronic pain before surgery (taking opioids)
  2. Patients with multiple trauma
  3. Patients who could not assess pain reliably (dementia)
  4. Patients who in anticoagulation
  5. Patient refused
  6. Infection at the side of injection

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm Type

    Experimental

    Experimental

    Arm Label

    treatment

    treatement

    Arm Description

    patient will recieve pericapsular nerve group block

    patient will receive lumbar erector spinae plane block

    Outcomes

    Primary Outcome Measures

    Duration of analgesia
    the time passed from block to the patient's first analgesic request in hours

    Secondary Outcome Measures

    Full Information

    First Posted
    September 10, 2021
    Last Updated
    April 22, 2022
    Sponsor
    Assiut University
    search

    1. Study Identification

    Unique Protocol Identification Number
    NCT05050487
    Brief Title
    Pericapsular Nerve Group Block Versus Lumber Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty
    Official Title
    Pericapsular Nerve Group Block Versus Lumber Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    April 2022
    Overall Recruitment Status
    Not yet recruiting
    Study Start Date
    June 30, 2022 (Anticipated)
    Primary Completion Date
    October 30, 2023 (Anticipated)
    Study Completion Date
    December 30, 2023 (Anticipated)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Principal Investigator
    Name of the Sponsor
    Assiut University

    4. Oversight

    Studies a U.S. FDA-regulated Drug Product
    No
    Studies a U.S. FDA-regulated Device Product
    No

    5. Study Description

    Brief Summary
    Pain is a major problem that has to be dealt with in case of hip fracture, as it presents an obstacle for examination, positioning for receiving neuroaxial anesthesia and postoperative mobility and physiotherapy. With the introduction of ultrasound in regional anesthesia and peripheral nerve blocks, regional analgesia float to the surface as a substitute for opioids with less side effects Lumbar erector spinae plane block has emerged as a reliable analgesic option for primary total hip arthroplasty (THA). In 2018, a new block was described, termed pericapsular nerve group block or PENG block, that selectively targets the articular branches of the femoral and obturator nerves while sparing their motor components
    Detailed Description
    Pain is a major problem that has to be dealt with in case of hip fracture, as it presents an obstacle for examination, positioning for receiving neuroaxial anesthesia and postoperative mobility and physiotherapy. With the introduction of ultrasound in regional anesthesia and peripheral nerve blocks, regional analgesia float to the surface as a substitute for opioids with less side effects Lumbar erector spinae plane block has emerged as a reliable analgesic option for primary total hip arthroplasty (THA). In 2018, a new block was described, termed pericapsular nerve group block or PENG block, that selectively targets the articular branches of the femoral and obturator nerves while sparing their motor components The pericapsular nerve group (PENG) block is an ultrasound-guided approach first de-scribed by Giron-Arango et al. for the blockade of the articular branches of the femoral (FN), obturator (ON) and accessory obturator (AON) nerve that provide sensory innervation to the an¬terior hip capsule. It has been developed as an alternative regional anesthesia technique for the management of acute pain after hip fractures, but its applications are expanding. Currently, the PENG block has been used to control and reduce pain in hip-related procedures. There are reports of PENG blocks used as surgical anesthetic techniques for hip arthroplasty (in combination with local anesthetic and intravenous analgesics) or hip arthroscopy (in combination with lateral femoral cutaneous nerve [LFCN] block). There is a report of a PENG block used as analgesic technique for sickle cell disease vaso-occlusive crisis and a PENG radiofrequency ablation for osteoarthritis analgesia. There are also reports about the use of a PENG block for non-hip related interventions, such as leg vein ligation and stripping, medial thigh surgery, prevention of adductor muscle spasm during transurethral resection of bladder and below-knee amputation in association with popliteal sciatic nerve block.These latter cases further extended the application of the PENG block beyond the hip-related area. So far, most of the reports describe preoperative or postoperative single-shot blocks, while there are only few case reports of continuous PENG blocks. Due to the novelty of this technique, there are still ongoing debates about the best injection point as well as the best anesthetic concentration and the total volume to be injected. Defined in the last decade, erector spinae plane block (ESPB) is one of the more frequently used interfacial plans, and it has been the most discussed block among the recently defined techniques. Lumbar ESPB administered at lumbar levels is relatively novel and is a new horizon for regional anesthesia and pain practice.(14)

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Post Operative Pain, Chronic

    7. Study Design

    Primary Purpose
    Prevention
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Model Description
    randomized controlled trail
    Masking
    None (Open Label)
    Allocation
    Randomized
    Enrollment
    60 (Anticipated)

    8. Arms, Groups, and Interventions

    Arm Title
    treatment
    Arm Type
    Experimental
    Arm Description
    patient will recieve pericapsular nerve group block
    Arm Title
    treatement
    Arm Type
    Experimental
    Arm Description
    patient will receive lumbar erector spinae plane block
    Intervention Type
    Procedure
    Intervention Name(s)
    PENG block
    Other Intervention Name(s)
    pericapsular nerve group block
    Intervention Description
    The PENG block is performed under US guid¬ance, . The pa¬tient is placed in the supine position a curvilinear low-fre¬quency ultrasound probe (2-5 MHz) is initially placed in a transverse plane over the AIIS and then aligned with the pubic ramus by rotating the probe approximately 30-45 degrees . . The needle, usually a 22-G80-mm echogenic device, is inserted from lateral to medial with an in-plane approach to place the tip in the plane between the psoas tendon anteriorly and the pu¬bic ramus posteriorly . After needle insertion and following negative aspiration, the local anesthetic is injected . The volume used of 20 ml of(L-bupivacaine; concentration 0,25% ) . This fascial plane appeared to continue in the hip pericapsular plane.
    Intervention Type
    Procedure
    Intervention Name(s)
    lumbar erector spinae plane block
    Other Intervention Name(s)
    ESPB
    Intervention Description
    The lumbar erector spinae block is performed under US guid¬ance, after adequate skin disinfection The patient is placed in the lateral decubitus position according to the selected site of surgical intervention. The 4th lumbar vertebral level will determined The convex USG transducer was placed at the mid-vertebral line in the sagittal plane. The transducer was shifted from the midline, 3.5-4 cm laterally to the side of the surgery to visualize the erector spinae muscle and transverse process . 0.5-1 ml of the prepared LA solution (20 ml bupivacaine 0.25%). All LA was administered to this location between the transverse process and the erector spinae muscle.
    Primary Outcome Measure Information:
    Title
    Duration of analgesia
    Description
    the time passed from block to the patient's first analgesic request in hours
    Time Frame
    24 hour

    10. Eligibility

    Sex
    All
    Minimum Age & Unit of Time
    18 Years
    Maximum Age & Unit of Time
    80 Years
    Accepts Healthy Volunteers
    No
    Eligibility Criteria
    Inclusion Criteria: ASA grade 1&2 &3 Adult patients (Age >18 yrs) Eligible patients were aged 18 years or older, were admitted for hip arthroplasty (THA or HA) for femoral neck fracture, and had undergone a preoperative RA technique (PENG block or lumbar erector spinae plane block) Exclusion Criteria: Patients with chronic pain before surgery (taking opioids) Patients with multiple trauma Patients who could not assess pain reliably (dementia) Patients who in anticoagulation Patient refused Infection at the side of injection
    Central Contact Person:
    First Name & Middle Initial & Last Name or Official Title & Degree
    Abdeltwab Younis
    Phone
    01098518513
    Email
    abdeltwabyonis91@gmail.com

    12. IPD Sharing Statement

    Learn more about this trial

    Pericapsular Nerve Group Block Versus Lumber Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty

    We'll reach out to this number within 24 hrs