Periodontal Therapy in Patients With Rheumatoid Arthritis
Arthritis, Rheumatoid, Periodontitis
About this trial
This is an interventional treatment trial for Arthritis, Rheumatoid focused on measuring C-reactive protein, Periodontal diseases, Periodontitis, Rheumatoid arthritis, Scaling and root planning
Eligibility Criteria
Inclusion Criteria:
- Patients of both sexes
- Age ≥16 years at the time of diagnosis and who do not meet criteria of overlap with any other autoimmune disease.
- Presence of six or more permanent teeth in the mouth, excluding third molars.
- Presence of periodontitis stage 3 or 4 with at least 2 non-adjacent teeth with insertion loss >=5mm, probing depth >=5mm and bleeding on probing according to Tonetti et al.[35].
- Willingness to attend all visits for the duration of the study.
Exclusion Criteria:
Patients with Sjogren's syndrome
- - Severe ongoing systemic infection.
- - Associated dental infection
- - History of oral cavity cancer or precancerous lesion.
- - Use of local or systemic antibiotics in the last 3 months (including tetracyclines or other medication that could change the periodontal evaluation in the investigator's opinion, such as heparin alendronate, antivitamin K).
- - Medications that induce gingival hyperplasia (such as phenytoin, warfarin or cyclosporine).
- - Pregnant or breastfeeding women
- - Participation in another intervention study.
- Patients with a history of PD treatment in the last 6 months or previous dental surgery)
Sites / Locations
- Universidad Cientifica del Sur
Arms of the Study
Arm 1
Arm 2
No Intervention
Active Comparator
Control
Non-surgical periodontal treatment
The control group will be comprised by those who will not receive any specific oral care intervention. For ethical reasons, the control group will receive periodontal therapy at the Endo of the study (after 6 months). In those cases presenting periodontal disease progression in a single tooth, the patients will be treated and withdrawn from the study
Periodontal treatment will be performed with scaling and root planning (SRP).SRP will be performed under local anesthesia during a single, 2-hour, full-mouth ultrasonic and hand instrument debridement using curettes. Oral hygiene instructions (patient education and motivation to control plaque and calculus accumulation)