Peripherical Neuromuscular Electrical Stimulation in Systemic Autoimmune Myopathies
Electrical Remodeling, Rheumatic Diseases, Myopathy
About this trial
This is an interventional other trial for Electrical Remodeling focused on measuring systemic autoimmune myopathies, Peripherical neuromuscular electrical stimulation, myositis
Eligibility Criteria
Inclusion Criteria:
- Classification criteria - EULAR/ACR 2017
- Classification criteria - Connors et al.
- Objective muscle limb weakness
Exclusion Criteria:
- Neoplasia
- Using heart pacemarker
- Using visceral metalic clips
- Infections (HIV, HTLV-1, Hepatitis, etc)
- Pregnancy
- Previous historical of convulsions or epilepsies
Sites / Locations
- Samuel K Shinjo
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Electrical stimulation
Placebo
After local antisepsis, 4 electrodes will be placed at the proximal and distal extremities of the lateral and vastus medialis muscles of dominant limb. A positive, single-phase pulsating (intermittent) current with a rectangular waveform will be delivered with a duty cycle of 10 to 15 seconds shutdown at a frequency of 60 Hertz with a pulse width of 400 microseconds for 30 minutes. To control the degree of muscle activation, electrical stimulation will be administered at an intensity that will consistently produce a target torque equal to 15% of maximal voluntary contraction, as monitored in real time through torque output. The desired intensity of stimulation and intensity adjustments throughout the treatment will be evaluated in all patients.
Patients will not submitted to electrical stimulation.