Pethidine Versus Nitrous Oxide for Pain Relief During Labor
Labor Pain
About this trial
This is an interventional treatment trial for Labor Pain focused on measuring Labor analgesia, Nitrous Oxide, Meperidine, Multiparous, Visual analogue scale
Eligibility Criteria
Inclusion Criteria:
- Multiparity (para 2 or more).
- Term pregnancy: 37-42 weeks of gestation.
- Singleton pregnancy.
- Vertex presentation.
- In labor: at least 2 contraction in ten minutes and cervical dilatation of 2 centimeters or more.
Exclusion Criteria:
- Women who desire epidural as a first line analgesia during labor.
- Women receiving pethidine during the last 24 hours (prior to entering labor room).
- Contra-indication for vaginal delivery.
- Contra-indication or allergic reaction to either pethidine or nitrous oxide.
- History of drug abuse.
- Previous cesarean delivery.
Sites / Locations
- HaEmek Medical Center
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
IV Meperidine
Inhaled Nitrous Oxide
Intravenous injection of meperidine 50mg given in 100cc NaCl 0.9% over 10 minutes. Repeated doses (if needed) will be given in intervals of 2 hours minimum until a maximum of 4 doses.
Nitrous oxide in a 50/50 mix with oxygen given via self-administered face mask. The parturient will be advised to place the mask tightly on her face and to breathe through it at the first sign of forthcoming uterine contraction. Between contractions, the parturient will be advised not to breath through the mask.