Pharmacokinetics and Safety/Tolerability of CKD-379
Type II Diabetes Mellitus
About this trial
This is an interventional treatment trial for Type II Diabetes Mellitus
Eligibility Criteria
Inclusion Criteria: Between 19 aged and 50 aged in healthy adult 50.0kg≤Body weight≤90.0kg and 18.0kg/m2≤body mass index(BMI)≤27.0kg/m2 Exclusion Criteria: Have clinical significant medical history or disease that hepatobiliary system, kidney, nervous system, immune system, respiratory system, digestive system, urinary system, endocrine system(Type I or Type II Diabetes Mellitus, diabetic ketoacidosis etc.), hematological system, cardiovascular system(heart failure, Torsades de pointes etc.), mental illness Have clinical significant medical history or disease that urinary tract infection or genital infection including urosepsis, pyelonephritis Have a gastrointestinal disease(Crohn's disease, ulcer etc.) history that can effect drug absorption or surgery Those who are pregnant or breastfeeding Those who are deemed inappropriate to participate in clinical trial by investigators
Sites / Locations
- Seoul National University Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Sequence 1
Sequence 2
Period 1: Reference drug(D759+D745+D150) Period 2: Test drug(CKD-379)
Period 1: Test drug(CKD-379) Period 2: Reference drug(D759+D745+D150)