Back to resultsPhase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease Mediated Proteinuric Kidney Disease (AMPLITUDE)
Primary Purpose
Proteinuric Kidney Disease
Status
Recruiting
Phase
Phase 2
Locations
International
Study Type
Interventional
Intervention
VX-147
Placebo
Sponsored by
About this trial
This is an interventional treatment trial for Proteinuric Kidney Disease
Eligibility Criteria
Key Inclusion Criteria:
- APOL1 genotype of G1/G1, G2/G2, or G1/G2
- Proteinuric kidney disease
Key Exclusion Criteria:
- Solid organ or bone marrow transplant
- Uncontrolled hypertension
- Diagnosis of diabetes mellitus
- Known underlying cause of kidney disease including but not limited to sickle cell disease
Other protocol defined Inclusion/Exclusion criteria apply.
Sites / Locations
- Nephrology Consultants, LLCRecruiting
- AKDHC Medical Research Service LLC - Banner Desert OfficeRecruiting
- AKDHC Medical Research Service LLC
- The Medical Research Group, IncRecruiting
- Cedars-Sinai Medical CenterRecruiting
- UCLA Division of NephrologyRecruiting
- UCI Center for Clinical ResearchRecruiting
- Kaiser Permanente, SacramentoRecruiting
- UCSF School of MedicineRecruiting
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterRecruiting
- Kidney and Hypertension CenterRecruiting
- Greater Hartford NephrologyRecruiting
- Nephrology & Hypertension Associates, PCRecruiting
- Yale UniversityRecruiting
- The George Washington University Medical Faculty Associates - Kidney Disease & HypertensionRecruiting
- Bay Pines Healthcare SystemRecruiting
- Nova Clinical Research, LLCRecruiting
- Clinical Research of Brandon, LLCRecruiting
- AMR-MiamiRecruiting
- Horizon Research Group, LLCRecruiting
- South Florida Nephrology Group PA, Research Div.Recruiting
- Delray Physician Care CenterRecruiting
- North Florida/South Georgia Veterans Health SystemRecruiting
- University of Florida, Shands HospitalRecruiting
- Velocity Clinical Research - Hallandale BeachRecruiting
- Qway ResearchRecruiting
- Elixia Pines, LLCRecruiting
- South Florida Research InstituteRecruiting
- Cordova Research InstituteRecruiting
- MedBio Trials
- Mid Florida Kidney and Hypertension Care, PLRecruiting
- Genesis Clinical ResearchRecruiting
- Elixia Tampa, LLCRecruiting
- Advanced Clinical Research of AtlantaRecruiting
- Morehouse School of Medicine, Grady Memorial HospitalRecruiting
- Children's Healthcare of Atlanta - Center for Advanced PediatricsRecruiting
- Fides Clinical ResearchRecruiting
- Medical College of Georgia (MCG)Recruiting
- Coastal Medical ResearchRecruiting
- Clincept - Warm SpringsRecruiting
- Renal Associates, LLCRecruiting
- Javara Inc./Privia Medical Group Georgia, PLLCRecruiting
- Georgia NephrologyRecruiting
- Inova Clinical Trials and Research CenterRecruiting
- NANI Research LLCRecruiting
- Essential Concepts Research SolutionsRecruiting
- Indiana UniversityRecruiting
- Nephrology Physicians, LLCRecruiting
- University of Kansas Medical CenterRecruiting
- Premier Clinical ResearchRecruiting
- Renal Associates of Baton RougeRecruiting
- Tulane University School of MedicineRecruiting
- University Medical Center - New OrleansRecruiting
- Ochsner Medical Center - New OrleansRecruiting
- Northwest Louisiana Nephrology, LLC - ShreveportRecruiting
- Javara Inc./Privia Medical Group, LLC MidAtlantic - Main Research SiteRecruiting
- University of Maryland Medical CenterRecruiting
- Johns Hopkins HospitalRecruiting
- Javara Inc./Privia Medical Group, LLC MidAtlantic-Silver Spring, MDRecruiting
- Tufts Medical CenterRecruiting
- Boston Medical CenterRecruiting
- Beth Israel Deaconess Medical CenterRecruiting
- Renal and Transplant Associates of New England, PCRecruiting
- Kidney Care and Transplant Services of New EnglandRecruiting
- University of Michigan Health System - A. Alfred Taubman Health Care Center - Nephrology ClinicRecruiting
- Henry Ford HospitalRecruiting
- AA Medical Research CenterRecruiting
- Sparrow Clinical Research InstituteRecruiting
- St. Clair Nephrology ResearchRecruiting
- InterMed ConsultantsRecruiting
- Minneapolis VA Healthcare SystemRecruiting
- Nephrology Associates, P.C.Recruiting
- University of MississippiRecruiting
- Nephrology and Hypertension Associates, LTDRecruiting
- Washington University Saint LouisRecruiting
- St. Louis Heart and Vascular, P.C.Recruiting
- Nevada Kidney Disease and Hypertension Centers
- Kidney Specialists of Southern NevadaRecruiting
- Rutgers New Jersey Medical SchoolRecruiting
- New Mexico VA Healthcare SystemRecruiting
- Renal Medicine Associates
- Albert Einstein Hospital - Montefiore Medical CenterRecruiting
- Kidney Medical Associates, PLLCRecruiting
- James J. Peters VA Medical CenterRecruiting
- SUNY Downstate Health Sciences UniversityRecruiting
- Nephrology Associates, P.C. - QueensRecruiting
- Zucker School of Medicine at Hofstra/NorthwellRecruiting
- Clinical Research Development Associates LLCRecruiting
- New York University Grossman School of MedicineRecruiting
- Icahn School of Medicine at Mount SinaiRecruiting
- Columbia University - Division of NephrologyRecruiting
- NYC Health + Hospital/HarlemRecruiting
- North Carolina Nephrology P.A. - Cary OfficeRecruiting
- UNC Clinical and Translational Research CenterRecruiting
- Eastern Nephrology Associates - Greenville OfficeRecruiting
- Eastern Nephrology Associates - Jacksonville OfficeRecruiting
- Eastern Nephrology Associates - Kinston OfficeRecruiting
- Eastern Nephrology Associates - New Bern OfficeRecruiting
- Eastern Nephrology Associates - Wilmington OfficeRecruiting
- Brookview Hills Research Associates
- Cincinnati VA Medical Center
- University Hospitals Cleveland Medical CenterRecruiting
- Cleveland ClinicRecruiting
- Ohio State UniversityRecruiting
- Thomas Jefferson UniversityRecruiting
- Temple University HospitalRecruiting
- Einstein Medical Center (NDKD)Recruiting
- Children's Hospital of Pittsburgh of UPMCRecruiting
- Lifespan Clinical Research CenterRecruiting
- Medical University of South CarolinaRecruiting
- Columbia Nephrology Associates, PARecruiting
- Carolina Nephrology, PARecruiting
- Southeast Renal Research InstituteRecruiting
- Vanderbilt University Medical Center, Nephrology Clinical Trials CenterRecruiting
- Dallas Renal Group - ArlingtonRecruiting
- Arlington NephrologyRecruiting
- Baylor Scott & White Research InstituteRecruiting
- Dallas Renal Group - 2Recruiting
- Nephrotex Research GroupRecruiting
- Dallas Renal Group - 1Recruiting
- Dallas Nephrology Associates - Dallas Landry OfficeRecruiting
- Davita Clinical Research - El PasoRecruiting
- Ronald Ralph MD PARecruiting
- Prolato Clinical Research CenterRecruiting
- Houston Medical Research Institute, LLCRecruiting
- Clinical Research Strategies - Romano North Main OfficeRecruiting
- Southwest Houston Research, LtdRecruiting
- Texas Tech University Health Sciences CenterRecruiting
- San Antonio Kidney
- University of Texas Health San AntonioRecruiting
- San Antonio KidneyRecruiting
- Kidney Specialists of N Houston, PLLCRecruiting
- Renal Physicians of Montgomery County, PARecruiting
- Tranquil Clinical ResearchRecruiting
- University of Virginia Health - Nephrology Clinical Research CenterRecruiting
- TKS Research, P.L.L.C.Recruiting
- York Clinical Research, LLCRecruiting
- Virginia Commonwealth University - Division of NephrologyRecruiting
- Nephrology Associates of Tidewater, LTDRecruiting
- Milwaukee Nephrologists, SCRecruiting
- Cliniques Universitaires Saint-LucRecruiting
- Santa Casa de Misericórdia de Belo HorizonteRecruiting
- Instituto Pro-RenalRecruiting
- PUC Trials - Unidade EpicenterRecruiting
- Unidade De Pesquisa Clinica Do Complexo Hospitalar Da UFCRecruiting
- Federal University of Goiás (UFG)Recruiting
- Cmip-Centro Mineiro de Pesquisa LtdaRecruiting
- Galileo Medical Research LtdaRecruiting
- Irmandade da Santa Casa de Misericórdia de Porto AlegreRecruiting
- UFRS - Hospital de ClínicasRecruiting
- Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao PauloRecruiting
- Hospital São LucasRecruiting
- Hospital Universitário Pedro ErnestoRecruiting
- Pedro Ernesto University HospitalRecruiting
- CSB Group of Nephrology BrazilRecruiting
- Fundação Faculdade Regional de Medicina de São José do Rio PretoRecruiting
- Hospital do Rim - Fundação Oswaldo Ramos - Ambulatorio NEFRITERecruiting
- University of Sao PauloRecruiting
- Recherche GCP ResearchRecruiting
- Women's College HospitalRecruiting
- Hopital Henri MondorRecruiting
- CHU Grenoble Alpes - Hôpital Nord MichallonRecruiting
- Hôpital Bicêtre AP-HPRecruiting
- CHU Dupuytren 2Recruiting
- Hôpital de la Conception, Centre de néphrologie et transplantation rénaleRecruiting
- Ambroise Paré HospitalRecruiting
- Hopitaux Universitaires Est Parisien - Hopital TenonRecruiting
- Service de Nephrologie - Hopital Universitaire NeckerRecruiting
- Université Paris-Descartes / Hôpital Européen Georges PompidouRecruiting
- AURA Nord Saint OuenRecruiting
- Centre Hospitalier Universitaire CHU de Toulouse Hopital de RangueilRecruiting
- Komfo Anokye Teaching HospitalRecruiting
- University of AmsterdamRecruiting
- Unidade Autónoma de NefrologiaRecruiting
- Hospital Curry CabralRecruiting
- Hospital Beatriz AngeloRecruiting
- GCM Medical Group, PSCRecruiting
- Hospital Clinic de BarcelonaRecruiting
- Hospital Universitari Vall d'HebronRecruiting
- Reina Sofia University HospitalRecruiting
- Hospital Universitario 12 de OctubreRecruiting
- Hospital Universitario Virgen MacarenaRecruiting
- University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth HospitalRecruiting
- Epsom and St Helier University Hospitals NHS Trust - St Helier Hospital - South West SW Thames Institute for Renal ResearchRecruiting
- University Hospitals of Leicester NHS Trust - Leicester General HospitalRecruiting
- Barts Health NHS Trust, The Royal London HospitalRecruiting
- Guy's & St Thomas NHS Foundation Trust, Guy's HospitalRecruiting
- Royal Free NHS TrustRecruiting
- St George's University Hospitals NHS Foundation TrustRecruiting
- Manchester Royal InfirmaryRecruiting
- The Medicines Evaluation UnitRecruiting
- Nottingham University HospitalRecruiting
- King's College Hospital NHS Foundation Trust - Guthrie ClinicRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm Type
Experimental
Placebo Comparator
Experimental
Placebo Comparator
Arm Label
Phase 2: VX-147
Phase 2: Placebo
Phase 3: VX-147
Phase 3: Placebo
Arm Description
Participants will be randomized to receive different dose levels of VX-147.
Participants will receive placebo matched to VX-147.
Participants will receive VX-147 with the dose to be based on the outcome of Phase 2.
Participants will receive placebo matched to VX-147.
Outcomes
Primary Outcome Measures
Percent Change From Baseline in Urine Protein to Creatinine Ratio (UPCR) at Week 48 (Assessed at the Week 48 Interim Analysis)
Estimated Glomerular Filtration Rate (eGFR) Slope Assessed at the Week 48 Interim Analysis
eGFR Slope Assessed at Study Completion
Secondary Outcome Measures
Time to Composite Clinical Outcome of a Sustained Decline of >=30 Percent (%) in eGFR, the Onset of end-stage Kidney Disease or Death
Safety and Tolerability as Assessed by Number of Participants With Adverse events (AEs) and Serious Adverse Events (SAEs)
Maximum Plasma Concentration (Cmax) of VX-147
Area Under the Concentration Versus Time Curve During a Dosing Interval (AUCtau) of VX-147
Observed Pre-dose Plasma Concentration (Ctrough) of VX-147
Acceptability Tablet Formulation of VX-147 in Pediatric Participants using the Convenience Domain of the Treatment Satisfaction Questionnaire for Medication (TSQM) Version 1.4
Full Information
NCT ID
NCT05312879
First Posted
March 28, 2022
Last Updated
October 17, 2023
Sponsor
Vertex Pharmaceuticals Incorporated
1. Study Identification
Unique Protocol Identification Number
NCT05312879
Brief Title
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease Mediated Proteinuric Kidney Disease
Acronym
AMPLITUDE
Official Title
A Phase 2/3 Adaptive, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of VX-147 in Adult and Pediatric Subjects With APOL1-mediated Proteinuric Kidney Disease
Study Type
Interventional
2. Study Status
Record Verification Date
February 2023
Overall Recruitment Status
Recruiting
Study Start Date
March 30, 2022 (Actual)
Primary Completion Date
May 2026 (Anticipated)
Study Completion Date
June 2026 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Vertex Pharmaceuticals Incorporated
4. Oversight
Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney disease.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Proteinuric Kidney Disease
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 2, Phase 3
Interventional Study Model
Sequential Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
466 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
Phase 2: VX-147
Arm Type
Experimental
Arm Description
Participants will be randomized to receive different dose levels of VX-147.
Arm Title
Phase 2: Placebo
Arm Type
Placebo Comparator
Arm Description
Participants will receive placebo matched to VX-147.
Arm Title
Phase 3: VX-147
Arm Type
Experimental
Arm Description
Participants will receive VX-147 with the dose to be based on the outcome of Phase 2.
Arm Title
Phase 3: Placebo
Arm Type
Placebo Comparator
Arm Description
Participants will receive placebo matched to VX-147.
Intervention Type
Drug
Intervention Name(s)
VX-147
Intervention Description
Tablets for oral administration.
Intervention Type
Drug
Intervention Name(s)
Placebo
Intervention Description
Tablets for oral administration.
Primary Outcome Measure Information:
Title
Percent Change From Baseline in Urine Protein to Creatinine Ratio (UPCR) at Week 48 (Assessed at the Week 48 Interim Analysis)
Time Frame
From Baseline at Week 48
Title
Estimated Glomerular Filtration Rate (eGFR) Slope Assessed at the Week 48 Interim Analysis
Time Frame
From Baseline Through >= Week 48
Title
eGFR Slope Assessed at Study Completion
Time Frame
From Baseline Through Study Completion (Approximately 2 Years After the Last Participant Enrolls)
Secondary Outcome Measure Information:
Title
Time to Composite Clinical Outcome of a Sustained Decline of >=30 Percent (%) in eGFR, the Onset of end-stage Kidney Disease or Death
Time Frame
From Baseline Through Study Completion (Approximately 2 Years After the Last Participant Enrolls)
Title
Safety and Tolerability as Assessed by Number of Participants With Adverse events (AEs) and Serious Adverse Events (SAEs)
Time Frame
Day 1 Through Study Completion (Approximately 2 Years After the Last Participant Enrolls)
Title
Maximum Plasma Concentration (Cmax) of VX-147
Time Frame
Day 1 and Week 40
Title
Area Under the Concentration Versus Time Curve During a Dosing Interval (AUCtau) of VX-147
Time Frame
Day 1 and Week 40
Title
Observed Pre-dose Plasma Concentration (Ctrough) of VX-147
Time Frame
Day 1 up to Week 40
Title
Acceptability Tablet Formulation of VX-147 in Pediatric Participants using the Convenience Domain of the Treatment Satisfaction Questionnaire for Medication (TSQM) Version 1.4
Time Frame
Day 1 and Week 48
10. Eligibility
Sex
All
Minimum Age & Unit of Time
10 Years
Maximum Age & Unit of Time
65 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Key Inclusion Criteria:
APOL1 genotype of G1/G1, G2/G2, or G1/G2
Proteinuric kidney disease
Key Exclusion Criteria:
Solid organ or bone marrow transplant
Uncontrolled hypertension
History of diabetes mellitus
Known underlying cause of kidney disease including but not limited to sickle cell disease
Other protocol defined Inclusion/Exclusion criteria apply.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Medical Information
Phone
617-341-6777
Email
medicalinfo@vrtx.com
Facility Information:
Facility Name
Nephrology Consultants, LLC
City
Huntsville
State/Province
Alabama
ZIP/Postal Code
35805
Country
United States
Individual Site Status
Recruiting
Facility Name
AKDHC Medical Research Service LLC - Banner Desert Office
City
Mesa
State/Province
Arizona
ZIP/Postal Code
85202
Country
United States
Individual Site Status
Recruiting
Facility Name
AKDHC Medical Research Service LLC
City
Phoenix
State/Province
Arizona
ZIP/Postal Code
85016
Country
United States
Individual Site Status
Withdrawn
Facility Name
The Medical Research Group, Inc
City
Fresno
State/Province
California
ZIP/Postal Code
93720
Country
United States
Individual Site Status
Recruiting
Facility Name
Cedars-Sinai Medical Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90048
Country
United States
Individual Site Status
Recruiting
Facility Name
UCLA Division of Nephrology
City
Los Angeles
State/Province
California
ZIP/Postal Code
90095
Country
United States
Individual Site Status
Recruiting
Facility Name
UCI Center for Clinical Research
City
Orange
State/Province
California
ZIP/Postal Code
92868
Country
United States
Individual Site Status
Recruiting
Facility Name
Kaiser Permanente, Sacramento
City
Sacramento
State/Province
California
ZIP/Postal Code
95825
Country
United States
Individual Site Status
Recruiting
Facility Name
UCSF School of Medicine
City
San Francisco
State/Province
California
ZIP/Postal Code
94143
Country
United States
Individual Site Status
Recruiting
Facility Name
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
City
Torrance
State/Province
California
ZIP/Postal Code
90502
Country
United States
Individual Site Status
Recruiting
Facility Name
Kidney and Hypertension Center
City
Victorville
State/Province
California
ZIP/Postal Code
92395
Country
United States
Individual Site Status
Recruiting
Facility Name
Greater Hartford Nephrology
City
Bloomfield
State/Province
Connecticut
ZIP/Postal Code
06002
Country
United States
Individual Site Status
Recruiting
Facility Name
Nephrology & Hypertension Associates, PC
City
Middlebury
State/Province
Connecticut
ZIP/Postal Code
06762
Country
United States
Individual Site Status
Recruiting
Facility Name
Yale University
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06510
Country
United States
Individual Site Status
Recruiting
Facility Name
The George Washington University Medical Faculty Associates - Kidney Disease & Hypertension
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20037
Country
United States
Individual Site Status
Recruiting
Facility Name
Bay Pines Healthcare System
City
Bay Pines
State/Province
Florida
ZIP/Postal Code
33744
Country
United States
Individual Site Status
Recruiting
Facility Name
Nova Clinical Research, LLC
City
Bradenton
State/Province
Florida
ZIP/Postal Code
34209
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Research of Brandon, LLC
City
Brandon
State/Province
Florida
ZIP/Postal Code
33511-5937
Country
United States
Individual Site Status
Recruiting
Facility Name
AMR-Miami
City
Coral Gables
State/Province
Florida
ZIP/Postal Code
33134
Country
United States
Individual Site Status
Recruiting
Facility Name
Horizon Research Group, LLC
City
Coral Gables
State/Province
Florida
ZIP/Postal Code
33134
Country
United States
Individual Site Status
Recruiting
Facility Name
South Florida Nephrology Group PA, Research Div.
City
Coral Springs
State/Province
Florida
ZIP/Postal Code
33071
Country
United States
Individual Site Status
Recruiting
Facility Name
Delray Physician Care Center
City
Delray Beach
State/Province
Florida
ZIP/Postal Code
33445
Country
United States
Individual Site Status
Recruiting
Facility Name
North Florida/South Georgia Veterans Health System
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32608
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Florida, Shands Hospital
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32610
Country
United States
Individual Site Status
Recruiting
Facility Name
Velocity Clinical Research - Hallandale Beach
City
Hallandale Beach
State/Province
Florida
ZIP/Postal Code
33009
Country
United States
Individual Site Status
Recruiting
Facility Name
Qway Research
City
Hialeah
State/Province
Florida
ZIP/Postal Code
33010
Country
United States
Individual Site Status
Recruiting
Facility Name
Elixia Pines, LLC
City
Hollywood
State/Province
Florida
ZIP/Postal Code
33024
Country
United States
Individual Site Status
Recruiting
Facility Name
South Florida Research Institute
City
Lauderdale Lakes
State/Province
Florida
ZIP/Postal Code
33313
Country
United States
Individual Site Status
Recruiting
Facility Name
Cordova Research Institute
City
Miami
State/Province
Florida
ZIP/Postal Code
33155
Country
United States
Individual Site Status
Recruiting
Facility Name
MedBio Trials
City
Miami
State/Province
Florida
ZIP/Postal Code
33180
Country
United States
Individual Site Status
Withdrawn
Facility Name
Mid Florida Kidney and Hypertension Care, PL
City
Sanford
State/Province
Florida
ZIP/Postal Code
32771
Country
United States
Individual Site Status
Recruiting
Facility Name
Genesis Clinical Research
City
Tampa
State/Province
Florida
ZIP/Postal Code
33603
Country
United States
Individual Site Status
Recruiting
Facility Name
Elixia Tampa, LLC
City
Temple Terrace
State/Province
Florida
ZIP/Postal Code
33637
Country
United States
Individual Site Status
Recruiting
Facility Name
Advanced Clinical Research of Atlanta
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30309
Country
United States
Individual Site Status
Recruiting
Facility Name
Morehouse School of Medicine, Grady Memorial Hospital
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30310
Country
United States
Individual Site Status
Recruiting
Facility Name
Children's Healthcare of Atlanta - Center for Advanced Pediatrics
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30322
Country
United States
Individual Site Status
Recruiting
Facility Name
Fides Clinical Research
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
Individual Site Status
Recruiting
Facility Name
Medical College of Georgia (MCG)
City
Augusta
State/Province
Georgia
ZIP/Postal Code
30912-3140
Country
United States
Individual Site Status
Recruiting
Facility Name
Coastal Medical Research
City
Brunswick
State/Province
Georgia
ZIP/Postal Code
31520
Country
United States
Individual Site Status
Recruiting
Facility Name
Clincept - Warm Springs
City
Columbus
State/Province
Georgia
ZIP/Postal Code
31904
Country
United States
Individual Site Status
Recruiting
Facility Name
Renal Associates, LLC
City
Columbus
State/Province
Georgia
ZIP/Postal Code
31904
Country
United States
Individual Site Status
Recruiting
Facility Name
Javara Inc./Privia Medical Group Georgia, PLLC
City
Fayetteville
State/Province
Georgia
ZIP/Postal Code
30214
Country
United States
Individual Site Status
Recruiting
Facility Name
Georgia Nephrology
City
Lawrenceville
State/Province
Georgia
ZIP/Postal Code
30046
Country
United States
Individual Site Status
Recruiting
Facility Name
Inova Clinical Trials and Research Center
City
Tyrone
State/Province
Georgia
ZIP/Postal Code
30290
Country
United States
Individual Site Status
Recruiting
Facility Name
NANI Research LLC
City
Evergreen Park
State/Province
Illinois
ZIP/Postal Code
60805
Country
United States
Individual Site Status
Recruiting
Facility Name
Essential Concepts Research Solutions
City
Palos Hills
State/Province
Illinois
ZIP/Postal Code
60465
Country
United States
Individual Site Status
Recruiting
Facility Name
Indiana University
City
Indianapolis
State/Province
Indiana
ZIP/Postal Code
46202
Country
United States
Individual Site Status
Recruiting
Facility Name
Nephrology Physicians, LLC
City
Mishawaka
State/Province
Indiana
ZIP/Postal Code
46545
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Kansas Medical Center
City
Kansas City
State/Province
Kansas
ZIP/Postal Code
66160
Country
United States
Individual Site Status
Recruiting
Facility Name
Premier Clinical Research
City
Overland Park
State/Province
Kansas
ZIP/Postal Code
66210
Country
United States
Individual Site Status
Recruiting
Facility Name
Renal Associates of Baton Rouge
City
Baton Rouge
State/Province
Louisiana
ZIP/Postal Code
70808
Country
United States
Individual Site Status
Recruiting
Facility Name
Tulane University School of Medicine
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70112
Country
United States
Individual Site Status
Recruiting
Facility Name
University Medical Center - New Orleans
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70112
Country
United States
Individual Site Status
Recruiting
Facility Name
Ochsner Medical Center - New Orleans
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70121
Country
United States
Individual Site Status
Recruiting
Facility Name
Northwest Louisiana Nephrology, LLC - Shreveport
City
Shreveport
State/Province
Louisiana
ZIP/Postal Code
71101
Country
United States
Individual Site Status
Recruiting
Facility Name
Javara Inc./Privia Medical Group, LLC MidAtlantic - Main Research Site
City
Annapolis
State/Province
Maryland
ZIP/Postal Code
21401
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Maryland Medical Center
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21201
Country
United States
Individual Site Status
Recruiting
Facility Name
Johns Hopkins Hospital
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21287
Country
United States
Individual Site Status
Recruiting
Facility Name
Javara Inc./Privia Medical Group, LLC MidAtlantic-Silver Spring, MD
City
Silver Spring
State/Province
Maryland
ZIP/Postal Code
20901
Country
United States
Individual Site Status
Recruiting
Facility Name
Tufts Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02111
Country
United States
Individual Site Status
Recruiting
Facility Name
Boston Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02118
Country
United States
Individual Site Status
Recruiting
Facility Name
Beth Israel Deaconess Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02215
Country
United States
Individual Site Status
Recruiting
Facility Name
Renal and Transplant Associates of New England, PC
City
Springfield
State/Province
Massachusetts
ZIP/Postal Code
01107
Country
United States
Individual Site Status
Recruiting
Facility Name
Kidney Care and Transplant Services of New England
City
West Springfield
State/Province
Massachusetts
ZIP/Postal Code
01089
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Michigan Health System - A. Alfred Taubman Health Care Center - Nephrology Clinic
City
Ann Arbor
State/Province
Michigan
ZIP/Postal Code
48109
Country
United States
Individual Site Status
Recruiting
Facility Name
Henry Ford Hospital
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48202
Country
United States
Individual Site Status
Recruiting
Facility Name
AA Medical Research Center
City
Flint
State/Province
Michigan
ZIP/Postal Code
48504
Country
United States
Individual Site Status
Recruiting
Facility Name
Sparrow Clinical Research Institute
City
Lansing
State/Province
Michigan
ZIP/Postal Code
48912
Country
United States
Individual Site Status
Recruiting
Facility Name
St. Clair Nephrology Research
City
Roseville
State/Province
Michigan
ZIP/Postal Code
48066
Country
United States
Individual Site Status
Recruiting
Facility Name
InterMed Consultants
City
Edina
State/Province
Minnesota
ZIP/Postal Code
55435
Country
United States
Individual Site Status
Recruiting
Facility Name
Minneapolis VA Healthcare System
City
Minneapolis
State/Province
Minnesota
ZIP/Postal Code
55417
Country
United States
Individual Site Status
Recruiting
Facility Name
Nephrology Associates, P.C.
City
Columbus
State/Province
Mississippi
ZIP/Postal Code
39705
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Mississippi
City
Grenada
State/Province
Mississippi
ZIP/Postal Code
38901
Country
United States
Individual Site Status
Recruiting
Facility Name
Nephrology and Hypertension Associates, LTD
City
Tupelo
State/Province
Mississippi
ZIP/Postal Code
38801
Country
United States
Individual Site Status
Recruiting
Facility Name
Washington University Saint Louis
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63130
Country
United States
Individual Site Status
Recruiting
Facility Name
St. Louis Heart and Vascular, P.C.
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63136
Country
United States
Individual Site Status
Recruiting
Facility Name
Nevada Kidney Disease and Hypertension Centers
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89106
Country
United States
Individual Site Status
Withdrawn
Facility Name
Kidney Specialists of Southern Nevada
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89128
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers New Jersey Medical School
City
Newark
State/Province
New Jersey
ZIP/Postal Code
07103
Country
United States
Individual Site Status
Recruiting
Facility Name
New Mexico VA Healthcare System
City
Albuquerque
State/Province
New Mexico
ZIP/Postal Code
87108
Country
United States
Individual Site Status
Recruiting
Facility Name
Renal Medicine Associates
City
Albuquerque
State/Province
New Mexico
ZIP/Postal Code
87109
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Albert Einstein Hospital - Montefiore Medical Center
City
Bronx
State/Province
New York
ZIP/Postal Code
10461-1900
Country
United States
Individual Site Status
Recruiting
Facility Name
Kidney Medical Associates, PLLC
City
Bronx
State/Province
New York
ZIP/Postal Code
10461
Country
United States
Individual Site Status
Recruiting
Facility Name
James J. Peters VA Medical Center
City
Bronx
State/Province
New York
ZIP/Postal Code
10468
Country
United States
Individual Site Status
Recruiting
Facility Name
SUNY Downstate Health Sciences University
City
Brooklyn
State/Province
New York
ZIP/Postal Code
11203
Country
United States
Individual Site Status
Recruiting
Facility Name
Nephrology Associates, P.C. - Queens
City
Flushing
State/Province
New York
ZIP/Postal Code
11365
Country
United States
Individual Site Status
Recruiting
Facility Name
Zucker School of Medicine at Hofstra/Northwell
City
Great Neck
State/Province
New York
ZIP/Postal Code
11021
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Research Development Associates LLC
City
Laurelton
State/Province
New York
ZIP/Postal Code
11413
Country
United States
Individual Site Status
Recruiting
Facility Name
New York University Grossman School of Medicine
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Individual Site Status
Recruiting
Facility Name
Icahn School of Medicine at Mount Sinai
City
New York
State/Province
New York
ZIP/Postal Code
10029
Country
United States
Individual Site Status
Recruiting
Facility Name
Columbia University - Division of Nephrology
City
New York
State/Province
New York
ZIP/Postal Code
10032
Country
United States
Individual Site Status
Recruiting
Facility Name
NYC Health + Hospital/Harlem
City
New York
State/Province
New York
ZIP/Postal Code
10037
Country
United States
Individual Site Status
Recruiting
Facility Name
North Carolina Nephrology P.A. - Cary Office
City
Cary
State/Province
North Carolina
ZIP/Postal Code
27511
Country
United States
Individual Site Status
Recruiting
Facility Name
UNC Clinical and Translational Research Center
City
Chapel Hill
State/Province
North Carolina
ZIP/Postal Code
27599-7155
Country
United States
Individual Site Status
Recruiting
Facility Name
Eastern Nephrology Associates - Greenville Office
City
Greenville
State/Province
North Carolina
ZIP/Postal Code
27834
Country
United States
Individual Site Status
Recruiting
Facility Name
Eastern Nephrology Associates - Jacksonville Office
City
Jacksonville
State/Province
North Carolina
ZIP/Postal Code
28546
Country
United States
Individual Site Status
Recruiting
Facility Name
Eastern Nephrology Associates - Kinston Office
City
Kinston
State/Province
North Carolina
ZIP/Postal Code
28504
Country
United States
Individual Site Status
Recruiting
Facility Name
Eastern Nephrology Associates - New Bern Office
City
New Bern
State/Province
North Carolina
ZIP/Postal Code
28562
Country
United States
Individual Site Status
Recruiting
Facility Name
Eastern Nephrology Associates - Wilmington Office
City
Wilmington
State/Province
North Carolina
ZIP/Postal Code
28401
Country
United States
Individual Site Status
Recruiting
Facility Name
Brookview Hills Research Associates
City
Winston-Salem
State/Province
North Carolina
ZIP/Postal Code
27103
Country
United States
Individual Site Status
Completed
Facility Name
Cincinnati VA Medical Center
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45220
Country
United States
Individual Site Status
Completed
Facility Name
University Hospitals Cleveland Medical Center
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44106
Country
United States
Individual Site Status
Recruiting
Facility Name
Cleveland Clinic
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44195
Country
United States
Individual Site Status
Recruiting
Facility Name
Ohio State University
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43201
Country
United States
Individual Site Status
Recruiting
Facility Name
Thomas Jefferson University
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19107
Country
United States
Individual Site Status
Recruiting
Facility Name
Temple University Hospital
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19140
Country
United States
Individual Site Status
Recruiting
Facility Name
Einstein Medical Center (NDKD)
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19141
Country
United States
Individual Site Status
Recruiting
Facility Name
Children's Hospital of Pittsburgh of UPMC
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15224
Country
United States
Individual Site Status
Recruiting
Facility Name
Lifespan Clinical Research Center
City
East Providence
State/Province
Rhode Island
ZIP/Postal Code
02915
Country
United States
Individual Site Status
Recruiting
Facility Name
Medical University of South Carolina
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29425
Country
United States
Individual Site Status
Recruiting
Facility Name
Columbia Nephrology Associates, PA
City
Columbia
State/Province
South Carolina
ZIP/Postal Code
29203
Country
United States
Individual Site Status
Recruiting
Facility Name
Carolina Nephrology, PA
City
Spartanburg
State/Province
South Carolina
ZIP/Postal Code
29306
Country
United States
Individual Site Status
Recruiting
Facility Name
Southeast Renal Research Institute
City
Chattanooga
State/Province
Tennessee
ZIP/Postal Code
37404
Country
United States
Individual Site Status
Recruiting
Facility Name
Vanderbilt University Medical Center, Nephrology Clinical Trials Center
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37232
Country
United States
Individual Site Status
Recruiting
Facility Name
Dallas Renal Group - Arlington
City
Arlington
State/Province
Texas
ZIP/Postal Code
76002
Country
United States
Individual Site Status
Recruiting
Facility Name
Arlington Nephrology
City
Arlington
State/Province
Texas
ZIP/Postal Code
76015
Country
United States
Individual Site Status
Recruiting
Facility Name
Baylor Scott & White Research Institute
City
Dallas
State/Province
Texas
ZIP/Postal Code
75204
Country
United States
Individual Site Status
Recruiting
Facility Name
Dallas Renal Group - 2
City
Dallas
State/Province
Texas
ZIP/Postal Code
75230
Country
United States
Individual Site Status
Recruiting
Facility Name
Nephrotex Research Group
City
Dallas
State/Province
Texas
ZIP/Postal Code
75231
Country
United States
Individual Site Status
Recruiting
Facility Name
Dallas Renal Group - 1
City
Dallas
State/Province
Texas
ZIP/Postal Code
75237
Country
United States
Individual Site Status
Recruiting
Facility Name
Dallas Nephrology Associates - Dallas Landry Office
City
Dallas
State/Province
Texas
ZIP/Postal Code
75246
Country
United States
Individual Site Status
Recruiting
Facility Name
Davita Clinical Research - El Paso
City
El Paso
State/Province
Texas
ZIP/Postal Code
79925
Country
United States
Individual Site Status
Recruiting
Facility Name
Ronald Ralph MD PA
City
Houston
State/Province
Texas
ZIP/Postal Code
77054-2101
Country
United States
Individual Site Status
Recruiting
Facility Name
Prolato Clinical Research Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77054
Country
United States
Individual Site Status
Recruiting
Facility Name
Houston Medical Research Institute, LLC
City
Houston
State/Province
Texas
ZIP/Postal Code
77074
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Research Strategies - Romano North Main Office
City
Houston
State/Province
Texas
ZIP/Postal Code
77090
Country
United States
Individual Site Status
Recruiting
Facility Name
Southwest Houston Research, Ltd
City
Houston
State/Province
Texas
ZIP/Postal Code
77099
Country
United States
Individual Site Status
Recruiting
Facility Name
Texas Tech University Health Sciences Center
City
Lubbock
State/Province
Texas
ZIP/Postal Code
79430
Country
United States
Individual Site Status
Recruiting
Facility Name
San Antonio Kidney
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Individual Site Status
Withdrawn
Facility Name
University of Texas Health San Antonio
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Individual Site Status
Recruiting
Facility Name
San Antonio Kidney
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78251
Country
United States
Individual Site Status
Recruiting
Facility Name
Kidney Specialists of N Houston, PLLC
City
Shenandoah
State/Province
Texas
ZIP/Postal Code
77384
Country
United States
Individual Site Status
Recruiting
Facility Name
Renal Physicians of Montgomery County, PA
City
The Woodlands
State/Province
Texas
ZIP/Postal Code
77384
Country
United States
Individual Site Status
Recruiting
Facility Name
Tranquil Clinical Research
City
Webster
State/Province
Texas
ZIP/Postal Code
77598
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Virginia Health - Nephrology Clinical Research Center
City
Charlottesville
State/Province
Virginia
ZIP/Postal Code
22908
Country
United States
Individual Site Status
Recruiting
Facility Name
TKS Research, P.L.L.C.
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Individual Site Status
Recruiting
Facility Name
York Clinical Research, LLC
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23540
Country
United States
Individual Site Status
Recruiting
Facility Name
Virginia Commonwealth University - Division of Nephrology
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23298
Country
United States
Individual Site Status
Recruiting
Facility Name
Nephrology Associates of Tidewater, LTD
City
Virginia Beach
State/Province
Virginia
ZIP/Postal Code
23454
Country
United States
Individual Site Status
Recruiting
Facility Name
Milwaukee Nephrologists, SC
City
Wauwatosa
State/Province
Wisconsin
ZIP/Postal Code
53226
Country
United States
Individual Site Status
Recruiting
Facility Name
Cliniques Universitaires Saint-Luc
City
Woluwe-Saint-Lambert
State/Province
Brussels
Country
Belgium
Individual Site Status
Recruiting
Facility Name
Santa Casa de Misericórdia de Belo Horizonte
City
Belo Horizonte
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Instituto Pro-Renal
City
Curitiba
Country
Brazil
Individual Site Status
Recruiting
Facility Name
PUC Trials - Unidade Epicenter
City
Curitiba
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Unidade De Pesquisa Clinica Do Complexo Hospitalar Da UFC
City
Fortaleza
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Federal University of Goiás (UFG)
City
Goiania
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Cmip-Centro Mineiro de Pesquisa Ltda
City
Juiz de Fora
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Galileo Medical Research Ltda
City
Juiz De Fora
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Irmandade da Santa Casa de Misericórdia de Porto Alegre
City
Porto Alegre
Country
Brazil
Individual Site Status
Recruiting
Facility Name
UFRS - Hospital de Clínicas
City
Porto Alegre
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo
City
Ribeirao Preto
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Hospital São Lucas
City
Rio de Janeiro
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Hospital Universitário Pedro Ernesto
City
Rio de Janeiro
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Pedro Ernesto University Hospital
City
Rio de Janeiro
Country
Brazil
Individual Site Status
Recruiting
Facility Name
CSB Group of Nephrology Brazil
City
Salvador
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Fundação Faculdade Regional de Medicina de São José do Rio Preto
City
São José do Rio Preto
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Hospital do Rim - Fundação Oswaldo Ramos - Ambulatorio NEFRITE
City
São Paulo
Country
Brazil
Individual Site Status
Recruiting
Facility Name
University of Sao Paulo
City
São Paulo
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Recherche GCP Research
City
Montreal
Country
Canada
Individual Site Status
Recruiting
Facility Name
Women's College Hospital
City
Toronto
Country
Canada
Individual Site Status
Recruiting
Facility Name
Hopital Henri Mondor
City
Créteil
Country
France
Individual Site Status
Recruiting
Facility Name
CHU Grenoble Alpes - Hôpital Nord Michallon
City
Grenoble
Country
France
Individual Site Status
Recruiting
Facility Name
Hôpital Bicêtre AP-HP
City
Le Kremlin Bicêtre
Country
France
Individual Site Status
Recruiting
Facility Name
CHU Dupuytren 2
City
Limoges
Country
France
Individual Site Status
Recruiting
Facility Name
Hôpital de la Conception, Centre de néphrologie et transplantation rénale
City
Marseille
ZIP/Postal Code
13385
Country
France
Individual Site Status
Recruiting
Facility Name
Ambroise Paré Hospital
City
Paris
Country
France
Individual Site Status
Recruiting
Facility Name
Hopitaux Universitaires Est Parisien - Hopital Tenon
City
Paris
Country
France
Individual Site Status
Recruiting
Facility Name
Service de Nephrologie - Hopital Universitaire Necker
City
Paris
Country
France
Individual Site Status
Recruiting
Facility Name
Université Paris-Descartes / Hôpital Européen Georges Pompidou
City
Paris
Country
France
Individual Site Status
Recruiting
Facility Name
AURA Nord Saint Ouen
City
Saint-Ouen
Country
France
Individual Site Status
Recruiting
Facility Name
Centre Hospitalier Universitaire CHU de Toulouse Hopital de Rangueil
City
Toulouse
Country
France
Individual Site Status
Recruiting
Facility Name
Komfo Anokye Teaching Hospital
City
Kumasi
Country
Ghana
Individual Site Status
Recruiting
Facility Name
University of Amsterdam
City
Amsterdam
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Unidade Autónoma de Nefrologia
City
Amadora
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Hospital Curry Cabral
City
Lisboa
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Hospital Beatriz Angelo
City
Loures
Country
Portugal
Individual Site Status
Recruiting
Facility Name
GCM Medical Group, PSC
City
San Juan
ZIP/Postal Code
00917
Country
Puerto Rico
Individual Site Status
Recruiting
Facility Name
Hospital Clinic de Barcelona
City
Barcelona
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitari Vall d'Hebron
City
Barcelona
Country
Spain
Individual Site Status
Recruiting
Facility Name
Reina Sofia University Hospital
City
Córdoba
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario 12 de Octubre
City
Madrid
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario Virgen Macarena
City
Seville
Country
Spain
Individual Site Status
Recruiting
Facility Name
University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital
City
Birmingham
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Epsom and St Helier University Hospitals NHS Trust - St Helier Hospital - South West SW Thames Institute for Renal Research
City
Carshalton
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
University Hospitals of Leicester NHS Trust - Leicester General Hospital
City
Leicester
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Barts Health NHS Trust, The Royal London Hospital
City
London
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Guy's & St Thomas NHS Foundation Trust, Guy's Hospital
City
London
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Royal Free NHS Trust
City
London
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
St George's University Hospitals NHS Foundation Trust
City
London
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Manchester Royal Infirmary
City
Manchester
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
The Medicines Evaluation Unit
City
Manchester
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Nottingham University Hospital
City
Nottingham
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
King's College Hospital NHS Foundation Trust - Guthrie Clinic
City
Southwark
Country
United Kingdom
Individual Site Status
Recruiting
12. IPD Sharing Statement
Plan to Share IPD
No
IPD Sharing Plan Description
Details on Vertex data sharing criteria and process for requesting access can be found at: https://www.vrtx.com/independent-research/clinical-trial-data-sharing
Learn more about this trial
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease Mediated Proteinuric Kidney Disease
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