Photodynamic Therapy for the Treatment of COVID-19
Photodynamic Therapy& Low Level Laser in Management of COVID 19
About this trial
This is an interventional treatment trial for Photodynamic Therapy& Low Level Laser in Management of COVID 19 focused on measuring photodynamic therapy, low level laser therapy, COVID 19 virus
Eligibility Criteria
Inclusion Criteria:
- Hospitalized patients with Positive COVID 19 test suffering from Fever, cough, shortness of breath, chills, muscle pain, the new loss of taste or smell, vomiting or diarrhea, and/or sore throat
Exclusion Criteria:
- Patients in critical cases who admitted to the ICU, bacterial pneumonia, and respiratory distress grade III, IV, and patients on a mechanical ventilator.
Sites / Locations
- Abeer Attia Tawfik
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
photobiomodulation group
photodynamic group
positive control
Laser watch Patients will be subjected to low-level laser (diode laser 980nm) for 30 minutes, the recommended dose based on the previous study is 20 J for 3 to 7 days. The laser device: Laser watched applied at the wrist on the radial artery. Laser acupuncture
Methylene blue injection USP 1% will be used as a photosensitizer in PDT. 0.1 to 0.2 mL of 1% solution per kilogram of body weight Methylene Blue (methylene blue injection) will be injected intravenously very slowly over a period of several minutes to After one hour apply Light dose: 100 - 200 J/cm2 50-100 mW/cm2. (50 mW/cm2 increased the phototoxic response as well as the fractionated light application). The session will be done twice per week Laser watched applied at the wrist on the radial artery.
This group will include patients who are subjected to conventional treatment