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Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana

Primary Purpose

HIV Infections

Status

Completed

Phase

Not Applicable

Locations

Botswana

Study Type

Interventional

Intervention

Cell phone text message

About this trial

This is an interventional supportive care trial for HIV Infections focused on measuring HIV, Antiretrovirals, Adherence, Text messaging, Antiretroviral adherence, Treatment experienced

Eligibility Criteria

21 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

HIV infected
21 years of age or older

Exclusion Criteria:

Subjects who do not intend to have continuous follow-up care and monthly medication refills at Independence Surgery for at least the next six months

Sites / Locations

Independence Surgery

Outcomes

Primary Outcome Measures

HIV medication adherence

Secondary Outcome Measures

Full Information

NCT ID

NCT01001741

First Posted

October 23, 2009

Last Updated

September 16, 2015

Sponsor

University of Pennsylvania

1. Study Identification

Unique Protocol Identification Number

NCT01001741

Brief Title

Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana

Official Title

A Pilot Study of Cellular Phone Text Message Reminders to Improve HIV Medication Adherence at Independence Surgery Clinic Gaborone, Botswana

Study Type

Interventional

2. Study Status

Record Verification Date

June 2010

Overall Recruitment Status

Completed

Study Start Date

June 2008 (undefined)

Primary Completion Date

August 2009 (Actual)

Study Completion Date

August 2009 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

University of Pennsylvania

4. Oversight

Data Monitoring Committee

5. Study Description

Brief Summary

While medication adherence is critical to successful treatment of HIV, there are few studies of interventions demonstrating improvements in adherence. This may be a particular challenge in the developing world, which has a larger burden of HIV but fewer resources than industrialized countries. The investigators propose a randomized controlled trial of cellular phone text message reminders to improve medication adherence. Our pilot study will be set in a large HIV clinic in Gaborone, Botswana, where Penn researchers have collaborated on research projects in the past. The primary study outcome will be antiretroviral medication adherence.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

HIV Infections

Keywords

HIV, Antiretrovirals, Adherence, Text messaging, Antiretroviral adherence, Treatment experienced

7. Study Design

Primary Purpose

Supportive Care

Study Phase

Not Applicable

Interventional Study Model

Parallel Assignment

Masking

None (Open Label)

Allocation

Randomized

Enrollment

128 (Actual)

8. Arms, Groups, and Interventions

Intervention Type

Other

Intervention Name(s)

Cell phone text message

Intervention Description

We will use cellular text messages to remind patients of impending drug prescription refills and scheduled visits to their healthcare provider.

Primary Outcome Measure Information:

Title

HIV medication adherence

Time Frame

Monthly

10. Eligibility

Sex

All

Minimum Age & Unit of Time

21 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: HIV infected 21 years of age or older Exclusion Criteria: Subjects who do not intend to have continuous follow-up care and monthly medication refills at Independence Surgery for at least the next six months

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Darren Linkin, MD

Organizational Affiliation

University of Pennsylvania

Official's Role

Study Director

First Name & Middle Initial & Last Name & Degree

Harvey Friedman, MD

Organizational Affiliation

University of Pennsylvania

Official's Role

Principal Investigator

First Name & Middle Initial & Last Name & Degree

James Thompson, MBA

Organizational Affiliation

Wharton Business School, UPenn

Official's Role

Study Director

First Name & Middle Initial & Last Name & Degree

Andrew Steenhoff

Organizational Affiliation

University of Pennsylvania

Official's Role

Study Director

Facility Information:

Facility Name

Independence Surgery

City

Gaborone

Country

Botswana

12. IPD Sharing Statement

Citations:

PubMed Identifier

24442231

Citation

Reid MJ, Dhar SI, Cary M, Liang P, Thompson J, Gabaitiri L, Steele K, Mayisela S, Dickinson D, Friedman H, Linkin DR, Steenhoff AP. Opinions and attitudes of participants in a randomized controlled trial examining the efficacy of SMS reminders to enhance antiretroviral adherence: a cross-sectional survey. J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):e86-8. doi: 10.1097/QAI.0b013e3182a9c72b. No abstract available.

Results Reference

result

Links:

URL

http://www.uphs.upenn.edu/idd/bots.html

Description

University of Pennsylvania in Botswana

Learn more about this trial

Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana

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