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Pilot Trial of Cognitive and Behavioral Treatment of Compulsive Hoarding Compared to Wait List Control

Primary Purpose

Obsessive-Compulsive Disorder

Status
Completed
Phase
Phase 1
Locations
United States
Study Type
Interventional
Intervention
Cognitive Behavioral Treatment
Sponsored by
Boston University Charles River Campus
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Obsessive-Compulsive Disorder focused on measuring Hoarding Disorder

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion criteria: Display at least moderately severe hoarding symptoms Must live within 45 minutes of Boston, MA or Hartford, CT Exclusion criteria: Ten or more sessions of cognitive behavior therapy for hoarding Concurrent psychotherapy or medications Suicidal, psychotic, or other psychiatric symptoms requiring hospitalization Compulsive buying symptoms that are part of a manic phase of bipolar disorder Mental retardation, dementia, brain damage, or other cognitive dysfunction that would interfere with the study

Sites / Locations

  • Hartford Hospital, Institute of Living
  • BostonUCRC

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

No Intervention

Arm Label

cognitive behavior therapy for hoarding disorder

Wait list control

Arm Description

Cognitive behavior therapy included 26 sessions of motivational enhancements; skills training for sorting, organizing and problem solving; direct practice not acquiring new items and discarding possessions to remove clutter and organize possessions; cognitive therapy to evaluate beliefs about possessions; and relapse prevention skills.

Participants waited to receive treatment for 12 weeks

Outcomes

Primary Outcome Measures

Saving Inventory-Revised
Self-report questionnaire of hoarding severity; total score range = 0 to 92; higher values indicate more symptoms

Secondary Outcome Measures

Hoarding Rating Scale
Interviewer measure with 5 questions to assess hoarding severity; total score range = 0 to 40; higher values indicate more symptoms

Full Information

First Posted
November 19, 2003
Last Updated
January 16, 2020
Sponsor
Boston University Charles River Campus
Collaborators
National Institute of Mental Health (NIMH)
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1. Study Identification

Unique Protocol Identification Number
NCT00073346
Brief Title
Pilot Trial of Cognitive and Behavioral Treatment of Compulsive Hoarding Compared to Wait List Control
Official Title
Cognitive and Behavioral Treatment of Compulsive Hoarding
Study Type
Interventional

2. Study Status

Record Verification Date
January 2020
Overall Recruitment Status
Completed
Study Start Date
September 1, 2003 (Actual)
Primary Completion Date
December 1, 2006 (Actual)
Study Completion Date
July 9, 2008 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Boston University Charles River Campus
Collaborators
National Institute of Mental Health (NIMH)

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
This study developed and tested a specialized cognitive and behavioral treatment for the symptoms of hoarding disorder, including excessive acquiring, difficulty discarding items, and extensive clutter in the home.
Detailed Description
Compulsive hoarding is characterized by excessive acquisition of possessions, difficulty discarding possessions, and excessive clutter. This condition is resistant to standard pharmacological and psychotherapeutic interventions that have proven effective in treating other obsessive compulsive spectrum disorders. This study aimed to determine the effectiveness of a specialized cognitive behavioral therapy (CBT) designed for treating hoarding symptoms. This study consists of three phases. In Phase 1, pilot data from previous studies were examined to develop an intervention suitable for use in a waitlist trial. In Phase 2, pilot study information were used to develop and test a treatment manual for compulsive hoarding. During this phase, treatment was applied flexibly to allow for variations in treatment duration and choice of techniques. During Phase 3, participants were randomly assigned to 26 weekly sessions of CBT or to a 12-week wait-list control, followed by active treatment for a fixed duration of 26 sessions. Therapist adherence and competence were assessed through audiotaped therapy sessions.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obsessive-Compulsive Disorder
Keywords
Hoarding Disorder

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 1
Interventional Study Model
Parallel Assignment
Model Description
active treatment versus wait list control
Masking
None (Open Label)
Allocation
Randomized
Enrollment
52 (Actual)

8. Arms, Groups, and Interventions

Arm Title
cognitive behavior therapy for hoarding disorder
Arm Type
Experimental
Arm Description
Cognitive behavior therapy included 26 sessions of motivational enhancements; skills training for sorting, organizing and problem solving; direct practice not acquiring new items and discarding possessions to remove clutter and organize possessions; cognitive therapy to evaluate beliefs about possessions; and relapse prevention skills.
Arm Title
Wait list control
Arm Type
No Intervention
Arm Description
Participants waited to receive treatment for 12 weeks
Intervention Type
Behavioral
Intervention Name(s)
Cognitive Behavioral Treatment
Primary Outcome Measure Information:
Title
Saving Inventory-Revised
Description
Self-report questionnaire of hoarding severity; total score range = 0 to 92; higher values indicate more symptoms
Time Frame
change from baseline to week 12; change from baseline to week 26
Secondary Outcome Measure Information:
Title
Hoarding Rating Scale
Description
Interviewer measure with 5 questions to assess hoarding severity; total score range = 0 to 40; higher values indicate more symptoms
Time Frame
change from baseline to week 12; change from baseline to week 26

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion criteria: Display at least moderately severe hoarding symptoms Must live within 45 minutes of Boston, MA or Hartford, CT Exclusion criteria: Ten or more sessions of cognitive behavior therapy for hoarding Concurrent psychotherapy or medications Suicidal, psychotic, or other psychiatric symptoms requiring hospitalization Compulsive buying symptoms that are part of a manic phase of bipolar disorder Mental retardation, dementia, brain damage, or other cognitive dysfunction that would interfere with the study
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Gail Steketee
Organizational Affiliation
Boston University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Hartford Hospital, Institute of Living
City
Hartford
State/Province
Connecticut
ZIP/Postal Code
06106
Country
United States
Facility Name
BostonUCRC
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02215
Country
United States

12. IPD Sharing Statement

Plan to Share IPD
No
IPD Sharing Plan Description
De-identified data have been shared with investigators working on hoarding relevant projects such as assessment of hoarding and meta-analyses of treatment outcome for hoarding disorder. Sharing of de-identified data will be considered upon request.
Links:
URL
http://www.ocfoundation.org
Description
Click here for more information about compulsive hoarding.

Learn more about this trial

Pilot Trial of Cognitive and Behavioral Treatment of Compulsive Hoarding Compared to Wait List Control

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