Predictors of Occult Atrial Fibrillation in 171 Patients With Cryptogenic TIA and Minor Stroke (HOLTER-21J)
Primary Purpose
Cryptogenic Transient Ischemic Attack and Minor Stroke
Status
Completed
Phase
Not Applicable
Locations
France
Study Type
Interventional
Intervention
Holter 21 days
Sponsored by
About this trial
This is an interventional prevention trial for Cryptogenic Transient Ischemic Attack and Minor Stroke
Eligibility Criteria
Inclusion Criteria:
- Cryptogenic TIA/Minor stroke
- Age > 18 years
- Medical care in Neuro Vascular Unit of CH Versailles
- Holter 21 days performed
Exclusion Criteria:
- ACFA history
- ECG or telemetry who showed ACFA before the Holter initializing
- Carotid Stenosis / symptomatic vertebral
- Arterial dissection
- Prothrombotic state demonstrated by laboratory tests
- Infective endocarditis
Sites / Locations
- Centre Hospitalier de Versailles
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
Patients taken care in neurovascular unit
Arm Description
Outcomes
Primary Outcome Measures
Number of atrial fibrillation detected on long duration ( 21 days) cardiac rythm holter monitoring
Atrial fibrillation >= 30 secondes
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT03166969
Brief Title
Predictors of Occult Atrial Fibrillation in 171 Patients With Cryptogenic TIA and Minor Stroke
Acronym
HOLTER-21J
Study Type
Interventional
2. Study Status
Record Verification Date
May 2017
Overall Recruitment Status
Completed
Study Start Date
February 2007 (undefined)
Primary Completion Date
January 2013 (Actual)
Study Completion Date
January 2013 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Versailles Hospital
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Retrospective study, single-center, on 171 patients, presented a cryptogenic TIA and Minor stroke.
This study objective is to determine profitability of Holter 21 days for screening paroxystic ACFA / flutter in cryptogenic TIA/Minor stroke, and identify the predictive factors of discovery a paroxystic ACFA on Holter 21 days. Clinical and échocardiographics factors, and brain imaging (scanner and MRI) will be analyzed.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Cryptogenic Transient Ischemic Attack and Minor Stroke
7. Study Design
Primary Purpose
Prevention
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
171 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Patients taken care in neurovascular unit
Arm Type
Experimental
Intervention Type
Procedure
Intervention Name(s)
Holter 21 days
Primary Outcome Measure Information:
Title
Number of atrial fibrillation detected on long duration ( 21 days) cardiac rythm holter monitoring
Description
Atrial fibrillation >= 30 secondes
Time Frame
Day 21
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Cryptogenic TIA/Minor stroke
Age > 18 years
Medical care in Neuro Vascular Unit of CH Versailles
Holter 21 days performed
Exclusion Criteria:
ACFA history
ECG or telemetry who showed ACFA before the Holter initializing
Carotid Stenosis / symptomatic vertebral
Arterial dissection
Prothrombotic state demonstrated by laboratory tests
Infective endocarditis
Facility Information:
Facility Name
Centre Hospitalier de Versailles
City
Le Chesnay
ZIP/Postal Code
78150
Country
France
12. IPD Sharing Statement
Plan to Share IPD
No
Citations:
PubMed Identifier
27495831
Citation
Sudacevschi V, Bertrand C, Chadenat ML, Tarnaud C, Pico F. Predictors of Occult Atrial Fibrillation in One Hundred Seventy-One Patients with Cryptogenic Transient Ischemic Attack and Minor Stroke. J Stroke Cerebrovasc Dis. 2016 Nov;25(11):2673-2677. doi: 10.1016/j.jstrokecerebrovasdis.2016.07.014. Epub 2016 Aug 2.
Results Reference
result
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Predictors of Occult Atrial Fibrillation in 171 Patients With Cryptogenic TIA and Minor Stroke
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