Prehabilitation for Prostate Cancer Surgery
Prostate Cancer Patients Undergoing Radical Prostatectomy
About this trial
This is an interventional supportive care trial for Prostate Cancer Patients Undergoing Radical Prostatectomy focused on measuring Prostate cancer, Radical prostatectomy, Prehabilitation, Pelvic floor muscle exercises
Eligibility Criteria
Inclusion Criteria:
- Men with localized prostate cancer (stage cT1- cT2) who have consented for radical prostatectomy
- between the ages of 40 and 80 years.
Exclusion Criteria:
- i) severe coronary artery disease (Canadian Cardiovascular Society class III or greater);
- ii) significant congestive heart failure (New York Heart Association class III or greater);
- iii) uncontrolled pain;
- iv) neurological or musculoskeletal co-morbidity inhibiting exercise;
- v) diagnosed psychotic, addictive, or major cognitive disorders;
- vi) no more than two of the following Coronary Risk Factors as defined by the American College of Sports Medicine : family history of coronary disease, cigarette smoking, hypertension (SBP > 140 mmHg; DBP > 90 mmHg), known dyslipidemia, known impaired fasting, glucose (>110 mg/dL), obesity (BMI > 30 kg/m2 or waist circumference > 102cm), or physically inactive (<150 min of moderate intensity physical activity per week).
Sites / Locations
- University Health Network
- McGill University Health Centre
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Healthy Lifestyle Booklet
Prehabilitation (PREHAB)
Standard care for radical prostatectomy (RP) patients includes the provision of preoperative information from a urology nurse educator. Usual care (UC) participants will be given generic instructions by the research coordinator about pelvic floor muscle exercises (PFMX), mobilization and general timeframes for a return to normal activities. The UC group will receive the same PFMX prescription as the PREHAB (Experimental) group and will receive weekly communication from the research coordinator regarding compliance with the PFMX prescription to provide an attentional-control. These instructions are provided in a healthy lifestyle booklet for men with prostate cancer.
The prehabilitation (PREHAB) program focuses on total-body physical exercises and pelvic floor muscle exercises (PFMX). The total-body exercise prescription will consist of 60 minutes of home-based, unsupervised exercise on 3-4 days per week, alternating between aerobic and resistance training. Each session will include: a 5-minute warm-up, 25 minutes of aerobic exercise, 25 minutes of resistance training (5 exercises targeting major muscle groups), and a 5-minute cool-down. Training intensity progression will occur throughout the intervention. Participants will be provided with resistance bands, a stability ball, and an exercise mat. The PFMX prescription will include a gradual increase in PFMX exercises from 60 per day during weeks 1-2, 120 per day during weeks 3-4, and 180 per day during weeks 5-6 until the surgery date. The total number of repetitions of the PFMXs will be divided equally between the rhythmic and sustained contractions.