Prenatal Dex Study (Prenatal Dex)
Congenital Adrenal Hyperplasia
About this trial
This is an interventional other trial for Congenital Adrenal Hyperplasia focused on measuring Congenital Adrenal Hyperplasia, Prenatal treatment, Dexamethasone, Neuropsychological assessment, Cognitive development
Eligibility Criteria
Inclusion Criteria:
Groups D+1, D+2, D-1 and D-2
- Male or female
- Patient with Congenital Adrenal Hyperplasia or sibling of a CAH patient
- Age: 6 to 15 years (at the time of inclusion)
- The subject's legal representatives have understood the information note/informed consent form, obtained answers to all their questions and have given signed, written, informed consent
- Subject with health insurance
Group D-3 (Schoolchildren)
- Male or female
- With no connection with Congenital Adrenal Hyperplasia
- Age: 6 to 15 years (at the time of inclusion)
- The subject's legal representatives have understood the information note/informed consent form, obtained answers to all their questions and have given signed, written, informed consent
- Subject with health insurance
Exclusion Criteria:
For all groups :
- Patient/Subject with another genetic disease
- Patient/Subject with known neuropsychology disease(s)
- Patient/Subject whose mother has received another treatment during her pregnancy with possible known adverse events on the neuropsychological development of the child
Sites / Locations
- Groupement Hospitalier Est - Laboratoire d'endocrinologie moléculaire et maladies rares - Centre de biologie et de pathologie Est. 59 boulevard PinelRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Experimental
Experimental
Active Comparator
Active Comparator
Other
Group D+ 1
Group D+ 2
: Group D - 1
Group D - 2
Group D - 3
Girls and boys at risk of CAH treated in utero by Dexamethasone but unaffected.
Girls and boys affected by CAH and treated in utero by Dexamethasone.
Girls and boys not affected by CAH and not treated in utero by Dexamethasone.
Girls and boys affected by CAH and not treated in utero by Dexamethasone.
Girls and boys enrolled in school closed to Lyon