Preventing Atopic Dermatitis and ALLergies in Children (PreventADALL)
Atopic Dermatitis, Food Allergy in Children, Asthma
About this trial
This is an interventional prevention trial for Atopic Dermatitis focused on measuring In-utero environment, Asthma, Allergic diseases, Food allergy, Birth cohort study, Primary prevention, Intervention study, Atopic dermatitis, Rhinitis, Allergy, Lung function, Non-communicable diseases, Foetal growth, Obesity, Cardiovascular disease, Diabetes, Blood pressure, Anthropometric, Trans epidermic water loss
Eligibility Criteria
The study enrolls Mother-child pairs in two steps; first mother, thereafter her new-born baby.
Inclusion Criteria:
1. Ante-natal inclusion, step 1: All mothers to-be at 18 weeks ultrasound investigation with sufficient language skills (Norwegian or Swedish), gestational age: at least 16-22 weeks.
1. Exclusion: Plans to move further than reasonable travel distance from any of the participating hospitals within the first year of the offspring's life.
1. Inclusion of the child, step 2: Live-born babies of gestational age 35.0 weeks or more (including multiple pregnancies), maternal/parental willingness to participate in the study
Exclusion Criteria:
Exclusion criteria child: 1) severe neonatal cardiac, pulmonary, neurologic, dermatologic disease or other disease that may influence the outcomes 2), plans to move further than reasonable travel distance away from any of the participating hospitals within the first nine months of life.
3) Non-willingness to participate, 4) More than two foetuses
Sites / Locations
- Oslo University Hospital and University of Oslo
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
No Intervention
Experimental
Experimental
Experimental
Observation only
Food intervention
Skin care
Food intervention and skin care
Observation only
Intervention; systematic introduction of egg, milk, wheat and peanut by 4 months of age
Intervention: regular baths with bath-oil 0.5-9 months of age
Intervention; systematic introduction of egg, milk, wheat and peanut by 4 months of age Intervention: regular baths with bath-oil 0.5-9 months of age