Preventing Urinary Tract Infections With E. Coli Nissle: (FinNissle)
Urinary Tract Infections in Children, Secondary Prevention
About this trial
This is an interventional prevention trial for Urinary Tract Infections in Children focused on measuring Urinary Tract Infections, E. coli
Eligibility Criteria
Inclusion Criteria:
- Children who suffer of the first urinary tract infection of their life defined as pyuria, presence of symptoms (fever or focal symptom), no other explanation for infection, bacterial culture positive or culture result pending
- Written informed consent
Exclusion Criteria:
- Preterm birth, gestational age less than 35 weeks
- Signs of life-threatening infection (such as meningitis)
- Detected anomaly in urinary tract
- Primary immunodeficiency
- Detected anomaly of GE tract
- Ongoing antimicrobial prophylaxis
- Hospital-acquired infection
Sites / Locations
- Helsinki University Hospital
- Kuopio University Hospital
- Department of Pediatrics, Oulu University HospitalRecruiting
- Tampere University Hospital
- Turku University Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Nissle group
Control group
Intervention will start on the day following the ending of the antimicrobial treatment of the UTI. Patients will receive 1 ml of oral suspension containing 10 E8 CFU/ml of E coli Nissle. Patients under one year of age will receive one daily dose and patients aged more than one year will receive a dose twice daily. Intervention will last for 30 days
Intervention will start on the day following the ending of the antimicrobial treatment of the UTI. Patients will receive 1 ml of oral syrup consisting of Saccharum 630 mg/g and Aqua purificata 370 mg/g. Patients under one year of age will receive one daily dose and patients aged more than one year will receive a dose twice daily. Intervention will last for 30 days