Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor 2
Labor Pain
About this trial
This is an interventional treatment trial for Labor Pain focused on measuring Epidural, Labor analgesia, Programmed intermittent epidural bolus
Eligibility Criteria
Inclusion Criteria:
- ASA 2 or 3
- Full term (≥ 37 weeks gestation)
- Nulliparous
- Singleton pregnancy, vertex presentation
- Active labor: regular painful contractions occurring at 3-at least every 5 minutes and change in cervix
- Verbal Numerical Pain Score (VNPS) at requesting analgesia > 5 (VNPS 0-10)
- Cervical dilatation ≥2 ≤ 5 cm
Exclusion Criteria:
- Refusal to provide written informed consent.
- Any contraindication to epidural anesthesia
- Unintentional dural puncture
- Allergy or hypersensitivity to bupivacaine or fentanyl
- Use of opioids or sedatives within the last 4 hours.
Sites / Locations
- Mount Sinai Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Experimental
60 minutes
50 minutes
40 minutes
30 minutes
The infusion pump will deliver programmed intermittent epidural boluses at a 60-minute interval. The bolus will consist of 5mL of 0.125% Bupivacaine plus fentanyl 2mcg/ml. A PCEA bolus of 5mL of 0.125% Bupivacaine plus fentanyl 2mcg/ml will also be available.
The infusion pump will deliver programmed intermittent epidural boluses at a 50-minute interval. The bolus will consist of 5mL of 0.125% Bupivacaine plus fentanyl 2mcg/ml. A PCEA bolus of 5mL of 0.125% Bupivacaine plus fentanyl 2mcg/ml will also be available.
The infusion pump will deliver programmed intermittent epidural boluses at a 40-minute interval. The bolus will consist of 5mL of 0.125% Bupivacaine plus fentanyl 2mcg/ml. A PCEA bolus of 5mL of 0.125% Bupivacaine plus fentanyl 2mcg/ml will also be available.
The infusion pump will deliver programmed intermittent epidural boluses at a 30-minute interval. The bolus will consist of 5mL of 0.125% Bupivacaine plus fentanyl 2mcg/ml. A PCEA bolus of 5mL of 0.125% Bupivacaine plus fentanyl 2mcg/ml will also be available.