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Rabies Treatment by Exposure of Patient to X-Ray

Primary Purpose

Treatment of Rabies

Status
Unknown status
Phase
Early Phase 1
Locations
Study Type
Interventional
Intervention
x ray exposure
Sponsored by
National Institute For Research On Endemic Diseases And Liver, Egypt
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Treatment of Rabies

Eligibility Criteria

undefined - undefined (Child, Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • patient bitten by rabid animal with signs and symptoms

Exclusion Criteria:

  • bitten by non rabid animal

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm 3

    Arm 4

    Arm Type

    Experimental

    Experimental

    Experimental

    Experimental

    Arm Label

    rabies patient 1

    rabies patient 2

    rabies patient 3

    rabies patient 4

    Arm Description

    not received immunoglobulins and symptomatic

    received immunoglobulins and symptomatic

    not received immunoglobulins and not yet symptomatic

    received immunoglobulins and not symptomatic

    Outcomes

    Primary Outcome Measures

    the number of rabies infected, symptomatic patients who survived after x-ray exposure
    detecting effect of x-ray exposure on treating Rabies

    Secondary Outcome Measures

    Full Information

    First Posted
    January 13, 2020
    Last Updated
    February 14, 2020
    Sponsor
    National Institute For Research On Endemic Diseases And Liver, Egypt
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    1. Study Identification

    Unique Protocol Identification Number
    NCT04261322
    Brief Title
    Rabies Treatment by Exposure of Patient to X-Ray
    Official Title
    Effect of X-ray on Rabies Virus in Vivo
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    February 2020
    Overall Recruitment Status
    Unknown status
    Study Start Date
    March 2020 (Anticipated)
    Primary Completion Date
    July 2020 (Anticipated)
    Study Completion Date
    July 2020 (Anticipated)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Principal Investigator
    Name of the Sponsor
    National Institute For Research On Endemic Diseases And Liver, Egypt

    4. Oversight

    Studies a U.S. FDA-regulated Drug Product
    No
    Studies a U.S. FDA-regulated Device Product
    No
    Product Manufactured in and Exported from the U.S.
    No

    5. Study Description

    Brief Summary
    x-ray has been proven to kill Rabies virus in vitro, so the investigators can use it in treatment of rabies infected patients.
    Detailed Description
    x-ray has been proven to kill Rabies virus in vitro, so the investigators can use it in treatment of rabies infected patients. this can be done by exposure of infected , manifested patient who didn't receive prophylaxis or delayed in receiving immunoglobulins . also can be applied to patients who have the injury in upper body near the CNS.. it's just an idea and the investigators need help to approve its effect and the investigators believe it will really work and give a new, rapid , cheap and very effective treatment to a 100% fatal disease.. the investigator also predict good results when x ray applied to some localized infections beside its current lines of treatment..

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Treatment of Rabies

    7. Study Design

    Primary Purpose
    Treatment
    Study Phase
    Early Phase 1
    Interventional Study Model
    Parallel Assignment
    Masking
    ParticipantInvestigator
    Allocation
    Non-Randomized
    Enrollment
    4 (Anticipated)

    8. Arms, Groups, and Interventions

    Arm Title
    rabies patient 1
    Arm Type
    Experimental
    Arm Description
    not received immunoglobulins and symptomatic
    Arm Title
    rabies patient 2
    Arm Type
    Experimental
    Arm Description
    received immunoglobulins and symptomatic
    Arm Title
    rabies patient 3
    Arm Type
    Experimental
    Arm Description
    not received immunoglobulins and not yet symptomatic
    Arm Title
    rabies patient 4
    Arm Type
    Experimental
    Arm Description
    received immunoglobulins and not symptomatic
    Intervention Type
    Radiation
    Intervention Name(s)
    x ray exposure
    Intervention Description
    exposure of whole body to x ray
    Primary Outcome Measure Information:
    Title
    the number of rabies infected, symptomatic patients who survived after x-ray exposure
    Description
    detecting effect of x-ray exposure on treating Rabies
    Time Frame
    7 month

    10. Eligibility

    Sex
    All
    Accepts Healthy Volunteers
    No
    Eligibility Criteria
    Inclusion Criteria: patient bitten by rabid animal with signs and symptoms Exclusion Criteria: bitten by non rabid animal
    Central Contact Person:
    First Name & Middle Initial & Last Name or Official Title & Degree
    Ahmed Samir El-Behwashy, fellowship
    Phone
    01001814806
    Email
    ahmedelsamir@gmail.com

    12. IPD Sharing Statement

    Plan to Share IPD
    Undecided

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    Rabies Treatment by Exposure of Patient to X-Ray

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