Radiological Investigation of Bile Duct Obstruction (RIBO)
Gallstone Disease
About this trial
This is an interventional diagnostic trial for Gallstone Disease focused on measuring Bile duct obstruction, intraoperative cholangiography, MRCP
Eligibility Criteria
Inclusion Criteria:
Patients presenting as regular admission or at the emergency department (ED) with cholecystolithiasis and suspected CBD stones. The indication for CBD investigation requires one of the following features:
i. Elevated bilirubin ii. ASAT/ALAT or gGT or aP above the normal range (two of them) iii. Choledocholithiasis in ultrasound iv. Dilated bile ducts in ultrasound
- Written informed consent
Exclusion Criteria:
- Age under 18 years
- Patients with biliary pancreatitis (due to the fact that conservative treatment is initiated before gallbladder removal and therefore leads to a prolonged hospital stay)
- Septic patients due to cholangitis
- Patients unable to consent
- Patients with medical conditions preventing surgery
- Pregnancy
- Radiologically proven CBD stone
Sites / Locations
- University Hospital Basel
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Cholecystectomy and intraoperative cholangiography
Magnet resonance cholangio-pancreaticography
Patients with suspected bile duct obstruction intraoperative cholangiography (IOC) to investigate bile ducts.
Patients get Magnet resonance cholangio-pancreaticography (MRCP) first. In case of detected gallstones, removal of the stones by endoscopic retrograde cholangiopancreaticography will be performed before gallbladder removal.