RC2S+: Remediation of Social Cognitive Impairments (RC2S+)
Schizophrenia
About this trial
This is an interventional treatment trial for Schizophrenia focused on measuring social cognition, cognitive remediation, emotions, theory of mind, attributions, social perception
Eligibility Criteria
Inclusion Criteria:
- Aged 18-45 years old
- Diagnosis of schizophrenia assessed with DSM5 criteria (APA, 2013)
- No modification of psychotropic treatment during the month before inclusion (variation of 20% of the dose is tolerated
- French native language or education in a French school since the first year of primary school
- Consent to participate to the study and agreement of the legal guardian
- Patients who have not benefited from cognitive remediation during the three months before inclusion
Exclusion Criteria:
- Substance use disorder (criteria of DSM-5), except for caffeine and tobacco
- Neurologic disorders (vascular, infectious or neurodegenerative)
- Uncorrected visual deficit
- Medical drugs with cerebral or psychological effect (e.g, corticosteroids)
- Patients resistant to antipsychotic medication
- Pregnancy
Sites / Locations
- centre de réhabilitation - Hôpital le Vinatier
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
RC2S+
Control therapy
RC2S+ Preparation sessions (sessions 1 & 2): Functional Outcomes Scale - Social Cognition (ERF-CS) Psychoeducation about social cognitive impairments Concrete objectives Cognitive remediation (sessions 3 to 22): Paper-and-pencil session Simulation session Home-based task Transfer sessions (sessions 23 & 24): Transfer of skills in dayly life - generalization Assessment of the achievement of objectives
Control therapy Preparation sessions (sessions 1 & 2): Functional Outcomes Scale - Neurocognition Psychoeducation about cognitive impairments Concrete objectives Cognitive remediation (sessions 3 to 24): Paper-and-pencil session Simulation session Home-based task