Real-Time Antiretroviral Therapy Adherence Intervention in Uganda
HIV/AIDS, Adherence
About this trial
This is an interventional health services research trial for HIV/AIDS focused on measuring HIV/AIDS, adherence, real time monitoring, SMS, mHealth, social support
Eligibility Criteria
Wisepill Participants:
Inclusion Criteria:
- HIV-infected
- Initiating ART within the next two weeks
- Age 18 years and older
- Owns a cell phone for personal use and has reliable cellular phone reception at home on a network supported by the technology used in this study
- Lives in the Mbarara District (i.e, within 20 km of the ISS Clinic)
- Has at least one person who could be named as a social supporter(see criteria below).
Exclusion Criteria:
- Unable to use SMS
- Unwilling to receive SMS reminders
- Severe mental condition limiting the ability to provide consent
- Cellular phone reception is not reliable
Social supporters (i.e., recipients of the SMS notifications for Wisepill participants in the intervention arms):
Inclusion criteria:
- Knows Wisepill participant has HIV
- Age 18 years or older
- Reports having provided social support to the intervention participant at least once
- Own a cell phone for personal use and have reliable cellular phone reception at home on a network supported by the technology used in this study
- Lives in the Mbarara District
Exclusion criteria:
- Unable to use SMS
- Unwilling to receive SMS notifications regarding interruptions in the intervention participant's adherence
- Severe mental condition limiting the ability to provide consent
Sites / Locations
- Mbarara Immune Suppression Syndrome(ISS) Clinic
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
No Intervention
Fixed SMS, real-time monitoring
Triggered SMS, real-time monitoring
control
SMS will be sent daily for one month, then weekly for two months. Participants will have real-time adherence monitoring and social supporters will be notified of gaps in adherence of 48+ hours in the last six months of the study.
Participants will have real-time adherence monitoring and social supporters will be notified of gaps in adherence of 48+ hours in the last six months of the study.
Real-time adherence monitoring only (no SMS)