search
Back to results

Recovery of Performance, Muscle Damage and Neuromuscular Fatigue Following Muscle Power Training (PoTrRec)

Primary Purpose

Power Training Exercise Protocols

Status
Terminated
Phase
Not Applicable
Locations
Greece
Study Type
Interventional
Intervention
Core exercises protocol
Structural exercises protocol
Accentuated eccentric load exercises protocol
Control condition
Sponsored by
University of Thessaly
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Power Training Exercise Protocols

Eligibility Criteria

18 Years - 35 Years (Adult)MaleAccepts Healthy Volunteers

Inclusion Criteria:

  • No recent history of musculoskeletal injury
  • No use of ergogenic supplements and drugs
  • No use of anti-inflammatory and antioxidant supplements (> 6 months)
  • No participation at intense eccentric exercise for at least 3 days before protocols

Exclusion Criteria:

  • Recent history of musculoskeletal injury
  • Use of ergogenic supplements and drugs
  • Use of anti-inflammatory and antioxidant supplements (< 6 months)
  • Participation at intense eccentric exercise for at least 3 days before protocols

Sites / Locations

  • Laboratory of Exercise Biochemistry, Exercise Physiology,and Sports Nutrition, School of Physical Education and Sport Science, University of Thessaly

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm Type

Experimental

Experimental

Experimental

Other

Arm Label

Core exercises protocol

Structural exercises protocol

Accentuated eccentric load exercises protocol

Control condition

Arm Description

Participants will perform 4 core exercises

Participants will perform 4 structural (Olympic lifting) exercises

Participants will perform 4 exercises with eccentric loading

Participants will perform all the measurements that are comprised in the experimental conditions without performing any exercise protocol

Outcomes

Primary Outcome Measures

Change on delayed onset of muscle soreness (DOMS), in the knee flexors (KF) and extensors (KE) of both limbs
Participants will perform three repetitions of a full squat movement, and rate their soreness level in knee flexors and extensors on a visual analog scale from 1 to 10 (VAS, with "no pain" at one end and "extremely sore" at the other), using palpation of the belly and the distal region of relaxed knee extensors and flexors.
Change on countermovement jump (CMJ) height
CMJ height will be measured in 3 maximal efforts (the best jump will be recorded) on an Ergojump contact platform
Change on isometric peak torque of the knee extensors (KE)
Isometric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Change on isometric peak torque of the knee flexors (KF)
Isometric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Change on concentric isokinetic peak torque of the knee extensors (KE)
Concentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Change on concentric isokinetic peak torque of the knee flexors (KF)
Concentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Change one eccentric isokinetic peak torque of the knee extensors (KE)
Eccentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Change on eccentric isokinetic peak torque of the knee flexors (KF)
Eccentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Change on the concentration of plasma CK activity
Plasma CK activity will be measured with a biochemical analyzer
Change on the concentration of blood lactate
Lactate will be measured with a portable lactate analyzer using capillary blood

Secondary Outcome Measures

Full Information

First Posted
April 30, 2019
Last Updated
December 30, 2020
Sponsor
University of Thessaly
search

1. Study Identification

Unique Protocol Identification Number
NCT03936595
Brief Title
Recovery of Performance, Muscle Damage and Neuromuscular Fatigue Following Muscle Power Training
Acronym
PoTrRec
Official Title
Investigation on the Recovery Kinetics of Performance, Muscle Damage and Neuromuscular Fatigue Indicators, Following Different Protocols for Muscle Power Development
Study Type
Interventional

2. Study Status

Record Verification Date
December 2020
Overall Recruitment Status
Terminated
Why Stopped
There was a high drop-out rate and we were unable to recruit new subjects.
Study Start Date
May 6, 2019 (Actual)
Primary Completion Date
June 16, 2019 (Actual)
Study Completion Date
June 28, 2019 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Thessaly

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No

5. Study Description

Brief Summary
Muscle power is one of the most important parameters in almost every athletic action, and expresses the ability of the human muscle to produce great amounts of force with the greatest possible speed. Thus, muscle power is critical for high performance in athletic actions such as jumping, throwing, change of direction and sprinting. For enhancing their muscle power, athletes comprise several resistance training programs as part of their training. Muscle power training comprises of eccentric muscle actions, and the magnitude of these actions depend on the emphasis that is given on the concentric or eccentric action, respectively, of the muscles during the exercises. However, eccentric muscle action, especially when unaccustomed, can lead to exercise-induced muscle damage (EIMD), and deterioration of muscle performance. Despite the fact that muscle power training comprises eccentric muscle actions, and consequently can lead to muscle injury and muscle performance reduction during the following days, the recovery kinetics after acute muscle power training have not been adequately studied. However, information regarding the recovery of the muscles after a power training protocol, is critical for the correct design of a training microcycle, and the reduction of injury risk. The aim of the present study is to investigate the muscle injury provoked after acute muscle power training using three different power training exercise protocols. Additionally, we will examine the effect of these protocols on muscle performance and neuromuscular fatigue indices.
Detailed Description
Muscle power is one of the most important parameters in almost every athletic action, and expresses the ability of the human muscle to produce great amounts of force with the greatest possible speed. Thus, muscle power is critical for high performance in athletic actions such as jumping, throwing, change of direction and sprinting. For enhancing their muscle power, athletes comprise several resistance training programs as part of their training. Core exercises as long as Olympic lifting has been used in muscle power training. The loads that are applied regarding the accomplishment of the most favorable power production are varying. Training load of 0% 1RM favored power production at the countermovement squat jump, while loads of 56% 1rm and 80% 1RM, favored the power production at squat and hang clean, respectively. Additionally, In the recent years, accentuated eccentric training has been proposed as a new training method for the enhancement of muscle power. This method emphasizes the eccentric component of the muscle contraction, and there is evidence supporting the greater production of muscle force after accentuated eccentric training compared with the typical resistance exercise training method. Taking the above into consideration, muscle power training comprises of eccentric muscle actions, and the magnitude of the eccentric component depends on the emphasis that is given on the concentric or eccentric action, respectively, of the muscles during the exercises. However, eccentric muscle action, especially when unaccustomed, can lead to exercise-induced muscle damage (EIMD). Although concentric and isometric exercise may also lead to muscle injury, the amount of damage after eccentric muscle contractions is greater. EIMD, amongst others, is accompanied by increased levels of creatine kinase (CK) into the circulation, increased delayed onset of muscle soreness (DOMS), reduction of force production, reduction of flexibility speed. Despite the fact that muscle power training comprises eccentric muscle actions, and consequently can lead to muscle injury and muscle performance reduction during the following days, the recovery kinetics after acute muscle power training protocols have not been adequately studied. However, information regarding the recovery of the muscles after a power training protocol, is critical for the correct design of a training microcycle, and the reduction of injury risk. The aim of the present study is to investigate the muscle injury provoked after muscle acute power training using three different power training exercise protocols. Additionally, the effect of these protocols on muscle performance and neuromuscular fatigue indices will be examined.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Power Training Exercise Protocols

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Crossover Assignment
Model Description
Each participant will perform in a random order all four different experimental conditions
Masking
None (Open Label)
Allocation
Randomized
Enrollment
10 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Core exercises protocol
Arm Type
Experimental
Arm Description
Participants will perform 4 core exercises
Arm Title
Structural exercises protocol
Arm Type
Experimental
Arm Description
Participants will perform 4 structural (Olympic lifting) exercises
Arm Title
Accentuated eccentric load exercises protocol
Arm Type
Experimental
Arm Description
Participants will perform 4 exercises with eccentric loading
Arm Title
Control condition
Arm Type
Other
Arm Description
Participants will perform all the measurements that are comprised in the experimental conditions without performing any exercise protocol
Intervention Type
Other
Intervention Name(s)
Core exercises protocol
Intervention Description
Participants will perform: Squats, 4 sets of 5 repetitions at 60% 1RM Deadlifts, 4 sets of 5 repetitions at 60% 1RM Lunges, 4 sets of 5 repetitions at 60% 1RM Step ups, 4 sets of 5 repetitions at 60% 1RM
Intervention Type
Other
Intervention Name(s)
Structural exercises protocol
Intervention Description
Participants will perform: Snatch, 4 sets of 5 repetitions at 60% 1RM Hang clean, 4 sets of 5 repetitions at 60% 1RM Push jerk, 4 sets of 5 repetitions at 60% 1RM Split push jerk, 4 sets of 5 repetitions at 60% 1RM
Intervention Type
Other
Intervention Name(s)
Accentuated eccentric load exercises protocol
Intervention Description
Participants will perform: Deadlifts - squat jump, 4 sets of 5 repetitions at 30% body mass (BM) Step down - squat jump, 4 sets of 5 repetitions at 30% BM Step down - lunges, 4 sets of 5 repetitions at 30% BM Hip thrusts, 4 sets of 5 repetitions at 30% BM
Intervention Type
Other
Intervention Name(s)
Control condition
Intervention Description
Participants will perform all the measurements that are comprised in the experimental conditions without performing any exercise protocol
Primary Outcome Measure Information:
Title
Change on delayed onset of muscle soreness (DOMS), in the knee flexors (KF) and extensors (KE) of both limbs
Description
Participants will perform three repetitions of a full squat movement, and rate their soreness level in knee flexors and extensors on a visual analog scale from 1 to 10 (VAS, with "no pain" at one end and "extremely sore" at the other), using palpation of the belly and the distal region of relaxed knee extensors and flexors.
Time Frame
Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Title
Change on countermovement jump (CMJ) height
Description
CMJ height will be measured in 3 maximal efforts (the best jump will be recorded) on an Ergojump contact platform
Time Frame
Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Title
Change on isometric peak torque of the knee extensors (KE)
Description
Isometric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Time Frame
Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Title
Change on isometric peak torque of the knee flexors (KF)
Description
Isometric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Time Frame
Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Title
Change on concentric isokinetic peak torque of the knee extensors (KE)
Description
Concentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Time Frame
Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Title
Change on concentric isokinetic peak torque of the knee flexors (KF)
Description
Concentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Time Frame
Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Title
Change one eccentric isokinetic peak torque of the knee extensors (KE)
Description
Eccentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Time Frame
Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Title
Change on eccentric isokinetic peak torque of the knee flexors (KF)
Description
Eccentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Time Frame
Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Title
Change on the concentration of plasma CK activity
Description
Plasma CK activity will be measured with a biochemical analyzer
Time Frame
Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Title
Change on the concentration of blood lactate
Description
Lactate will be measured with a portable lactate analyzer using capillary blood
Time Frame
Prior to, and immediately after the end of the experimental protocol

10. Eligibility

Sex
Male
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
35 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: No recent history of musculoskeletal injury No use of ergogenic supplements and drugs No use of anti-inflammatory and antioxidant supplements (> 6 months) No participation at intense eccentric exercise for at least 3 days before protocols Exclusion Criteria: Recent history of musculoskeletal injury Use of ergogenic supplements and drugs Use of anti-inflammatory and antioxidant supplements (< 6 months) Participation at intense eccentric exercise for at least 3 days before protocols
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Ioannis G Fatouros, PhD
Organizational Affiliation
University of Thessaly
Official's Role
Principal Investigator
Facility Information:
Facility Name
Laboratory of Exercise Biochemistry, Exercise Physiology,and Sports Nutrition, School of Physical Education and Sport Science, University of Thessaly
City
Trikala
State/Province
Thessaly
ZIP/Postal Code
42100
Country
Greece

12. IPD Sharing Statement

Citations:
PubMed Identifier
17277599
Citation
Cormie P, McCaulley GO, Triplett NT, McBride JM. Optimal loading for maximal power output during lower-body resistance exercises. Med Sci Sports Exerc. 2007 Feb;39(2):340-9. doi: 10.1249/01.mss.0000246993.71599.bf.
Results Reference
background
PubMed Identifier
22288008
Citation
Baird MF, Graham SM, Baker JS, Bickerstaff GF. Creatine-kinase- and exercise-related muscle damage implications for muscle performance and recovery. J Nutr Metab. 2012;2012:960363. doi: 10.1155/2012/960363. Epub 2012 Jan 11.
Results Reference
background
PubMed Identifier
28165870
Citation
Deli CK, Fatouros IG, Paschalis V, Georgakouli K, Zalavras A, Avloniti A, Koutedakis Y, Jamurtas AZ. A Comparison of Exercise-Induced Muscle Damage Following Maximal Eccentric Contractions in Men and Boys. Pediatr Exerc Sci. 2017 Aug;29(3):316-325. doi: 10.1123/pes.2016-0185. Epub 2017 Feb 6.
Results Reference
background
PubMed Identifier
16007451
Citation
Jamurtas AZ, Theocharis V, Tofas T, Tsiokanos A, Yfanti C, Paschalis V, Koutedakis Y, Nosaka K. Comparison between leg and arm eccentric exercises of the same relative intensity on indices of muscle damage. Eur J Appl Physiol. 2005 Oct;95(2-3):179-85. doi: 10.1007/s00421-005-1345-0. Epub 2005 Jul 9.
Results Reference
background
PubMed Identifier
15679573
Citation
Kyrolainen H, Avela J, McBride JM, Koskinen S, Andersen JL, Sipila S, Takala TE, Komi PV. Effects of power training on muscle structure and neuromuscular performance. Scand J Med Sci Sports. 2005 Feb;15(1):58-64. doi: 10.1111/j.1600-0838.2004.00390.x.
Results Reference
background
PubMed Identifier
27199764
Citation
Walker S, Blazevich AJ, Haff GG, Tufano JJ, Newton RU, Hakkinen K. Greater Strength Gains after Training with Accentuated Eccentric than Traditional Isoinertial Loads in Already Strength-Trained Men. Front Physiol. 2016 Apr 27;7:149. doi: 10.3389/fphys.2016.00149. eCollection 2016.
Results Reference
background

Learn more about this trial

Recovery of Performance, Muscle Damage and Neuromuscular Fatigue Following Muscle Power Training

We'll reach out to this number within 24 hrs