Recurrent Respiratory Papillomatosis and Extraesophageal Reflux
Recurrent Respiratory Papillomatosis, Extra Oesophageal Reflux, Laryngeal Cyst
About this trial
This is an interventional treatment trial for Recurrent Respiratory Papillomatosis focused on measuring recurrent respiratory papillomatosis, extra oesophageal reflux, laryngeal cyst, phonosurgery, oesophageal impedance
Eligibility Criteria
Inclusion Criteria:
- age 1-75 years
- cooperating patients with laryngeal papillomatosis
- patients tolerating impedance probe
- signed informed consent, consent with the examinations
- control group of patients with a cyst or vocal cord polyp (reflux finding score 0-2) and/or patients indicated to augmentation, medialization or lateralization of the vocal cords
Exclusion Criteria:
- patients non-tolerating impedance catheter
- patients who do not understand Czech language
- patients who do not proclaim consent with enrolment into the study
- patients who do not proclaim consent with the planned examinations
- patients after surgical treatment of tumour of the swallowing or respiratory tract
Sites / Locations
- University Hospital Ostrava
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Recurrent respiratory papillomatosis
Laryngeal cyst - control group
Patients with recurrent respiratory papillomatosis (RRP) - surgical collection of histology specimen from the vocal cords and rear laryngeal commissure, performance of immunohistochemical analysis - proof of pepsin, HPV 6 and 11, herpes simplex virus (HSV) type 2, chlamydia trachomasis, and assessment of the dysplasia.
Patients with laryngeal cyst - surgical collection of a histology specimen from the vocal cords and rear laryngeal commissure, performance of immunohistochemical analysis - proof of pepsin and HPV 6 and 11, herpes simplex virus (HSV) type 2 and chlamydia trachomasis.