Regeneration of Alveolar Sockets With rhBMP-2-loaded Bovine Bone Mineral (PROTEOGRAFT)
Loss of Teeth Due to Extraction, Alveolar Bone Loss, Edentulous Alveolar Ridge
About this trial
This is an interventional treatment trial for Loss of Teeth Due to Extraction focused on measuring Alveolar Bone Loss, Alveolar Ridge Augmentation, Bone Regeneration, Bone Morphogenetic Protein 2, Hydroxyapatite
Eligibility Criteria
Inclusion Criteria: Healthy patients with one tooth to be extracted, from incisor to premolar, and with buccal bone wall loss of 5 mm or more Plaque index lower than 30% Eighteen (18) years old and elder. Willing to participate and written informed consent Exclusion Criteria: Heavy smokers (more than 20 cigarettes per day) Plaque index greater than 30 % Pathologies hindering interventions or influencing healing or host response Inability to comply scheduled follow-up Comprehension disability that compromises informed consent and compliance with medical instructions Receptor of any other experimental treatments, actual or in past 30 days Current pregnant patients or planning to get pregnant in short term Breastfeeding mothers
Sites / Locations
- Faculty of Dentistry, Universidad Complutense de MadridRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Experimental
Control
Socket preservation after extraction with Proteo-Graft (Noricum S.L.) with a particle size of 0.25-1.00 mm, without using a barrier membrane.
Conventional treatment (socket preservation therapy). Post-extraction socket preservation with Bio-Oss® (Geistlich Pharma AG, Switzerland) with a particle size of 0.25-1.00 mm, hereinafter BO, and protection with a barrier membrane, Bio-Gide® ( Geistlich Pharma AG, Switzerland).