Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis

Inclusion Criteria: Periodontal disease stage III-IV, according to criteria the American Academy of Periodontology (AAP) with at least 3 mm interdental clinical attachment level (CAL) in the site of greatest loss. ≥ 18 years old Presence of ≥20 teeth, including implants Agreement to participate in the study and to sign a written consent form Able to co-operate with the treatment protocol and avoid any other oral hygiene measures outside of the study protocol Exclusion Criteria: Grade A or C periodontitis Presence of any physical limitation or restriction that might restrict Lumoral use Pregnancy or lactation Active smoking Medicated diabetes mellitus (DM) Any systemic disease (e.g., wound healing dysfunctions) that could alter the progression of periodontal disease Use of antibiotics within 4 weeks week prior study Periodontal treatment within 3 months prior study Removable major prosthesis or major orthodontic appliance A need for a hopeless teeth extraction, or open cavities in need for immediate endodontic treatment