Repetitive Transcranial Magnetic Stimulation as a Treatment for Tinnitus (rTMS)
Tinnitus
About this trial
This is an interventional treatment trial for Tinnitus focused on measuring tinnitus
Eligibility Criteria
Inclusion Criteria:
- Diagnosis of chronic tinnitus
- Chronic subjective tinnitus for more than 6 months
- Subject is naive regarding rTMS
- Other concurrent treatments: A four-week washout from any other tinnitus treatment or management program is required prior to entering this study
- Stable enough to complete this study per the opinion of the Study Physician
- No restrictions, provided the dosages have been in place for at least 3 months
- A three month washout from any other tinnitus treatment or management program is required prior to entering this study.
Exclusion Criteria:
- Objective tinnitus or tinnitus with treatable cause
- Presence of intracranial or intraocular ferromagnetic materiel or particles
- Cardiac pacemaker or other electronic implants (including cochlear implant) Serious heart disease or other unstable major medical condition
- Personal history of central nervous system disorder, head injury, stroke or seizures
- Familial history of epilepsy
- Concomitant medication with antidepressants and antipsychotics
- Pregnant women
- Others known contraindications to rTMS or brain MRI
Sites / Locations
- Seoul National University Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Sham Comparator
Active rTMS1
Active rTMS2
Active rTMS3
Sham Condition
Combined low frequency frontal and temporal repetitive transcranial magnetic stimulation of left primary auditory cortex and left dorsolateral prefrontal cortex
Temporal low frequency repetitive transcranial magnetic stimulation of left primary auditory cortex
Frontal low frequency repetitive transcranial magnetic stimulation of left dorsolateral prefrontal cortex
Combined low frequency frontal and temporal repetitive transcranial magnetic stimulation of left primary auditory cortex and left dorsolateral prefrontal cortex