Research on Community Based ATK Test Study to Control Spread of COVID-19 in Migrant Community (CATK)
COVID-19 Pandemic
About this trial
This is an interventional prevention trial for COVID-19 Pandemic focused on measuring COVID-19, Thailand, ATK, SARS-CoV-2 antigen rapid diagnostic testing
Eligibility Criteria
For Ag RDT arm (primary objective)
Inclusion Criteria
- *Symptomatic COVID-19 patient/suspected COVID-19 or **close contact/family members of COVID-19 patient
- Participant at any age living in chosen clusters of Maramat and Pohphra Myanmar migrant community
- Participant or parent/guardian/caretaker is willing and able to give informed consent for participation in the study.
Exclusion Criteria
- Known history of a COVID-19 positive test result within the last 21 days
For No Ag RDT arm (primary objective)
Inclusion Criteria
- Participant at any age living in chosen cluster of Maramat and Pohphra Myanmar migrant community
- Symptomatic COVID-19 patient/suspected COVID-19 or **close contact/family members of COVID-19 patient who agrees to go for routine Thai COVID-19 ATK or RT-PCR test
- Participant or parent/guardian/caretaker is willing and able to give informed consent for participation in the study
Exclusion Criteria
- Not living in chosen clusters in Maramat and Pohphra Myanmar migrant community
note: *Symptomatic or suspected COVID-19: Acute onset of ANY THREE OR MORE of the following signs or symptoms: Fever, cough, general weakness/fatigue1, headache, myalgia, sore throat, coryza, dyspnoea, anorexia/nausea/vomiting1, diarrhoea, altered mental status (1 Signs separated with slash (/) are to be counted as one sign) Reference: WHO-2019-nCoV-Surveillance_Case_Definition-2020.2-eng (5).pdf
note: **1 Person who stayed close to or had conversation with COVID-19 patient(s) for >5 minutes, or was exposed to the patient's cough or sneeze; 2 Individual who stayed in enclosed spaces with poor ventilation together with COVID-19 patient(s) for >30 minutes, for instance, in air-conditioned bus, commuter vane, or air-conditioned room; Reference: g_HCWs_3Mar22.pdf (moph.go.th)
For seroprevalence survey (secondary objective)
Inclusion Criteria
- Participant at any age living in chosen clusters of Maramat and Pohphra Myanmar migrant community
- Participant or parent/guardian/caretaker is willing and able to give informed consent for participation in the study.
Exclusion Criteria
- Refusal to give informed consent, or contraindication to venepuncture
For Focus group discussion (FGD)
Inclusion Criteria
- Age 18 years and above
- Living in chosen clusters of Maramat and Pohphra migrant communities
- Participant is willing and able to give informed consent for participation in the study.
Exclusion Criteria
- Not living in chosen clusters of Maramat and Pohphra migrant communities
Sites / Locations
- Shoklo Malaria Research Unit
Arms of the Study
Arm 1
Arm 2
Active Comparator
No Intervention
Ag-RDT (arm 1)
No Ag-RDT (arm 2)
Symptomatic /suspected COVID-19 participant or close contact/family members of COVID-19 patient will be tested with Ag RDT and also involve in awareness-raising campaign with mask distribution.
No community based Ag RDT testing but there has routine ATK or RT-PCR test by Thai health authorities if local health volunteer finds symptomatic or suspected COVID-19 or close contact with positive cases in their villages. The participant also involves in awareness-raising campaign with mask distribution.