Role of Exercise in Depression in Middle Aged and Older Adults (RED)
Depression
About this trial
This is an interventional prevention trial for Depression focused on measuring Depression, Biomarkers, Exercise
Eligibility Criteria
Inclusion Criteria:
46 or older English speaking Community dwelling Access to a private room Access to a telephone Permanent address Willingness to be randomized Internet-enabled computer in home or willingness to have such installed Score of 10 or more on PHQ-9 Major depressive disorder as indicated by the Structured Clinical Interview for DSM-IV (SCID) Primary care provider approval for participation in moderate-intensity exercise
Exclusion Criteria:
Any serious medical condition for which exercise is contraindicated by the ACSM Current diagnosis of one of the following: psychosis, bipolar disorder, lupus, HIV, AIDS, IBS, Crones, Rheumatoid Arthritis or related conditions, cancer or treatment for cancer within the last year. Acute illness Terminal illness (not expected to live beyond one year) Unwillingness to provide informed consent Unwillingness to donate blood Receiving disability insurance Currently engaged in professional psychotherapy Currently engaged in regular exercise Pregnant or nursing in the past 6 months, or plans to become so within 12 months Enrolled in another study Member of household enrolled in the same study Residence outside of Marion County Residence relocation plans within 12 months Substance abuse Suicide ideation as indicated by the PHQ-9
Sites / Locations
- Indiana University School of Medicine
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Low Exercise Arm
Public Health Exercise
Low dose exercise (50 Minutes)
Public Health dose exercise (150 minutes)