S0340 MRI and Fludeoxyglucose F18 PET in Diagnosing Solitary Plasmacytoma
Multiple Myeloma, Plasmacytoma
About this trial
This is an interventional other trial for Multiple Myeloma focused on measuring extramedullary plasmacytoma, isolated plasmacytoma of bone
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically confirmed solitary plasmacytoma of 1 of the following types: Solitary bone plasmacytoma Extraosseus solitary plasmacytoma Bone marrow plasmacytosis < 10% within the past 4 weeks Low serum and/or urine M-protein meeting ≥ 1 of the following criteria: Serum IgG < 3.5 g/dL Serum IgA < 2.0 g/dL Urine M-protein (kappa or lambda) < 1.0 g/24 hours No lytic lesions on skeletal survey other than a single lesion associated with solitary plasmacytoma within the past 4 weeks PATIENT CHARACTERISTICS: Age 18 and over Performance status Zubrod 0-2 Life expectancy Not specified Hematopoietic Hemoglobin ≥ 10 g/dL* AND/OR No hemoglobin 2 g/dL < lower limit of normal* (LLN) NOTE: *Patients with a history of hemoglobin < 10 g/dL AND/OR < 2 g/dL < LLN that has corrected or improved after epoetin alfa but requires continued treatment with epoetin alfa are not eligible Hepatic Not specified Renal Calcium ≤ 10.5 mg/dL OR Calcium normal Creatinine ≤ 2 mg/dL Other No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix or breast, or stage I or II cancer that is currently in complete remission PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy Not specified Endocrine therapy No prior high-dose steroids except to relieve neurological compromise Radiotherapy Prior localized radiotherapy for myeloma allowed Concurrent radiotherapy allowed Surgery Prior surgery for myeloma allowed Other No other prior therapy for myeloma Concurrent enrollment in protocol SWOG-S0309 (Myeloma Specimen Repository) allowed
Sites / Locations
- Mobile Infirmary Medical Center
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
- Tammy Walker Cancer Center at Salina Regional Health Center
- University of Michigan Comprehensive Cancer Center
- CCOP - Montana Cancer Consortium
- Hematology-Oncology Centers of the Northern Rockies - Billings
- Northern Rockies Radiation Oncology Center
- St. Vincent Healthcare
- Billings Clinic Cancer Center
- Deaconess Billings Clinic - Downtown
- Bozeman Deaconess Cancer Center
- St. James Community Hospital
- Big Sky Oncology
- Sletten Regional Cancer Institute at Benefis Healthcare
- St. Peter's Hospital
- Glacier Oncology, PLLC
- Kalispell Medical Oncology
- Kalispell Regional Medical Center
- Community Medical Center
- Guardian Oncology and Center for Wellness
- Montana Cancer Specialists at Montana Cancer Center
- Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
- Wayne Memorial Hospital, Incorporated
- Wayne Radiation Oncology
- Wilson Medical Center
- Welch Cancer Center at Sheridan Memorial Hospital
Arms of the Study
Arm 1
Other
MRI and PET
Magnetic resonance imaging and positron emission tomography