Safety and Efficacy of Cocktail Periarticular Injection in Simultaneous Total Knee Arthroplasty
Pain, Postoperative
About this trial
This is an interventional treatment trial for Pain, Postoperative focused on measuring total knee arthroplasty, cocktail analgesia, morphine consumption
Eligibility Criteria
Inclusion Criteria:
- patients with tricompartmental knee disease undergoing simultaneous bilateral TKA
Exclusion Criteria:
- diabetes mellitus
- neuromuscular deficit
- a known allergy to one of the drugs being injected
- a history of cardiac disease or arrhythmia requiring special monitoring
Sites / Locations
- Peking Union Medical College Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
cocktail analgesia
no cocktail injection
The local infiltration mixture of ropivacaine, fentanyl, adrenaline is used intra-articularly during operation. The patients in the cocktail analgesia group received an injection of 200mg ropivacaine, 100ug fentanyl, and 0.25mg adrenaline into knee collateral ligaments, posterior aspect of the capsule, quadriceps tendon, patellar tendon, fat pad, periosteum, and synovium, along with PCIA morphine postoperatively.
The patients in the no cocktail injection group received PCIA morphine postoperatively.