Safety, Tolerability, and Pharmacokinetics of ID119031166M With the Exploration of Pharmacodynamic Effects

Inclusion Criteria: Must be Caucasian (White American of European or Latin American descent). Healthy participants of Japanese origin are allowed up to 50% in each MAD cohort. Body mass index (BMI) within the range of 18.5 to 30 kg/m^2 (inclusive) at the time of Screening. No congenital or chronic diseases that require treatment and without pathologic symptoms or signs on medical examinations. Participants with normal renal function. Women are eligible to participate if not pregnant, not breastfeeding. Male subjects should be willing to use 'highly effective' or 'applicable' contraceptive methods. Exclusion Criteria: Currently have an acute disease with active symptoms. History of melanoma or other skin issues (including, but not limited to pre-cancerous areas, atopic dermatitis, psoriasis, rosacea, excessive moles etc.). History of clinically significant gastrointestinal, renal, hepatic, neurologic, hematologic, endocrine, oncologic, pulmonary, immunologic, psychiatric, musculoskeletal, or cardiovascular disease and/or arrhythmias. History of clinically significant hypersensitivity reaction to any drugs or additives. History of any gastrointestinal disease. History of substance use disorder including history of drug abuse disorder or history of alcohol use disorder, or tobacco use disorder or excessive caffeine intake. Evidence of moderate or excessive alcohol consumption. Tested positive in viral serology tests (hepatitis B virus [HBV], hepatitis C virus [HCV], and human immunodeficiency virus [HIV]). Known family history or known presence of long QT syndrome. A history of hypokalemia. Use of concomitant medicines that prolong QT/QTc (QT Interval Corrected for Heart Rate). History of active viral hepatitis (hepatitis A, B, C, and E), or autoimmune hepatitis. History of Multiple Endocrine Neoplasia type 2. Solid organ transplantation, except corneal transplants. History or presence of neutropenia which is defined as absolute neutrophil count (ANC) < 1.5 at Screening and admission. Participants with a microalbuminuria.