SCO2T (Servo vs. Servo)
Premature Infant, Oxygen Therapy, Hypoxia
About this trial
This is an interventional treatment trial for Premature Infant focused on measuring Servo Control, Close-Loop Automated Oxygen Control
Eligibility Criteria
Inclusion Criteria:
- Infants born at less than 30 weeks gestation
- Infants greater than 48 hours of age
- Infants who are receiving supplementary oxygen
- Person with parental responsibility able to give consent
Exclusion Criteria:
- Congenital anomalies that would prevent targeting SpO2 to 90-95% (e.g. cardiac defects)
- Clinical condition of an infant would impair accurateTcPO2 measurement (e.g. impaired perfusion or requirement of inotropic or vasopressor support)
Sites / Locations
- The Simpson Centre for Reproductive Health, Royal Infirmary Edinburgh
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Servo control - Leoni plus CLAC
Servo control - IntellO2 Precision Flow, Vapotherm
Automated control of oxygen. The oxygen saturation target range will be set to 90-95% as per standard practice. Automated oxygen control can be overridden by manual adjustment of oxygen at any time if this is considered necessary to optimise control of oxygenation according to current clinical targets.
Automated control of oxygen. The oxygen saturation target range will be set to 90-95% (set to maintain an integral value of 93%) as per standard practice. Automated oxygen control can be overridden by manual adjustment of oxygen at any time if this is considered necessary to optimise control of oxygenation according to current clinical targets.