Selective Image Guided Resection of Axillary Lymph Nodes
Breast Cancer
About this trial
This is an interventional diagnostic trial for Breast Cancer focused on measuring Breast Cancer, Invasive breast cancer, Axillary lymph node metastases, Ultrasound, Fine needle aspiration, FNA, Lymph node surgery, Partial mastectomy, Total mastectomy
Eligibility Criteria
Inclusion Criteria:
- Greater than or equal to 18 years old.
- Histologic diagnosis of invasive breast cancer, clinical stage T0-3 N1 (maximum one or two abnormal axillary nodes on ultrasound exam) M0.
- FNA biopsy (or core needle biopsy) of an axillary node documenting nodal disease at time of diagnosis and prior to preoperative chemotherapy or surgery.
- Marker clip placed in the one or two abnormal axillary nodes identified at ultrasound.
Exclusion Criteria:
1) Prior axillary lymph node surgery for pathological confirmation of axillary status.
Sites / Locations
- University of Texas MD Anderson Cancer Center
Arms of the Study
Arm 1
Other
Ultrasound + Breast Surgery + Lymph Node Removal
Patient receives an ultrasound of lymph nodes at diagnosis and on the day of surgery. Marker clip(s) placed using a needle in the abnormal lymph node(s). If patient received chemotherapy before surgery, fine needle aspiration (FNA) performed of any abnormal lymph nodes either right before or during standard breast and underarm surgery. To perform FNA, area is numbed with anesthetic and a needle is inserted into the affected area so that cells can be collected. Standard breast and underarm surgery (underarm lymph node removal and either a partial mastectomy or total mastectomy with or without reconstruction) performed.