Short Course Terlipressin for Control of Acute Variceal Bleeding
Hemorrhage, Esophageal Varices, Portal Hypertension
About this trial
This is an interventional treatment trial for Hemorrhage focused on measuring Esophageal varices, Portal Hypertension, Melena, Hematemesis, Gastrointestinal Hemorrhage, Terlipressin, Efficacy, Safety
Eligibility Criteria
Inclusion Criteria: Acute esophageal variceal bleed Liver cirrhosis Child's score </= 11 Exclusion Criteria: Patient on Mechanical ventilator and or ionotropic support Active angina, Recent Myocardial infarction or dynamic EKG changes Failure to control variceal bleed on initial endoscopy Gastric variceal bleed Spontaneous bacterial peritonitis at presentation Hepatocellular carcinoma or other liver metastatic malignancy Portal vein thrombosis
Sites / Locations
- The Aga Khan University Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
1
2
72 hours of Terlipressin
24 hours of Terlipressin & then next 48 hours of Dummy of Terlipressin