STRONG for Surgery & Strong for Life - Against All Odds: Intensive Prehabilitation for Risk Reduction in Cancer Surgery (STRONG-CS)
Risk Reduction, Urological Cancer, Surgery
About this trial
This is an interventional treatment trial for Risk Reduction focused on measuring Postoperative complications, Prehabilitation, Surgical risk reduction, Smoking, Alcohol drinking, Physical activity, Malnutrition, Obesity, Patient preferences, Randomised controlled trial
Eligibility Criteria
Inclusion Criteria:
- Patients > 18 years scheduled for cystectomy due to bladder cancer
- Referral to neoadjuvant chemotherapy
- Screened positive for minimum 1 SNAP factor
- Signed informed consent
Exclusion Criteria:
- Pregnancy and breastfeeding
- Allergy to pharmaceutical support (Nicotine Replacement Therapy, Disulfiram)
- Contraindications to exercise.
Sites / Locations
- Dept Urology 2112, Copenhagen University Hospital, RigshospitaletRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Prehabilitation
Treatment as usual
Intervention: Patients allocated to the intervention group receive weekly counselling sessions in 6 weeks as an integrated prehabilitation program tailored to meet the individual patient's need for risk reduction at surgery. It is introduced via the surgical 'Engage in the process of change'. The smoking and alcohol cessation intervention follows the Gold Standard Programme and patients in the intervention group are introduced to a standardized exercise training programme taking individualized needs into account. Nutritional support is also individualized.
Treatment as ususal covers shorter interventions, e.g. advice, brief counselling, and handing out the national folders on smoking and alcohol and surgery. Patients are ensured that they are free to access support to lifestyle changes in the community.